Patents by Inventor Andrew L. Glasebrook

Andrew L. Glasebrook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of inhibiting CNS problems in post-menopausal women
    Patent number: 6417198
    Abstract: A method of inhibiting one or more CNS disorders in a post-menopausal woman comprising administering to a female human in need of treatment an effective amount of a compound having the formula wherein R1 and R3 are independently hydrogen, wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: December 21, 1993
    Date of Patent: July 9, 2002
    Assignee: Eli Lilly and Company
    Inventors: Henry U. Bryant, Andrew L. Glasebrook, Timothy A. Grese, David L. Phillips
  • Methods of inhibiting myeloperoxidase activity
    Patent number: 5708009
    Abstract: A method of inhibiting myeloperoxidase activity or a physiological condition associated with an excess thereof, comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## or ##STR3## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: December 21, 1993
    Date of Patent: January 13, 1998
    Assignee: Eli Lilly and Company
    Inventor: Andrew L. Glasebrook
  • Methods of inhibiting myeloperoxidase activity
    Patent number: 5708010
    Abstract: A method of inhibiting myeloperoxidase activity or a physiological condition associated with an excess thereof, comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: May 18, 1995
    Date of Patent: January 13, 1998
    Assignee: Eli Lilly and Company
    Inventor: Andrew L. Glasebrook
  • Methods of inhibiting CNS problems in post-menopausal women
    Patent number: 5663184
    Abstract: A method of inhibiting one or more CNS disorders in a post-menopausal woman comprising administering to a female human in need of treatment an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: April 28, 1995
    Date of Patent: September 2, 1997
    Assignee: Eli Lilly and Company
    Inventors: Henry U. Bryant, Andrew L. Glasebrook, Timothy A. Grese, David L. Phillips
  • Methods of inhibiting demyelinating and dysmyelinating diseases
    Patent number: 5530010
    Abstract: A method of inhibiting demyelinating or dysmyelinating diseases or their symptoms comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: February 2, 1995
    Date of Patent: June 25, 1996
    Assignee: Eli Lilly and Company
    Inventor: Andrew L. Glasebrook
  • Methods of inhibiting viral replication
    Patent number: 5494920
    Abstract: A method of inhibiting viral replication comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: August 22, 1994
    Date of Patent: February 27, 1996
    Assignee: Eli Lilly and Company
    Inventors: Andrew L. Glasebrook, David L. Phillips
  • Methods of inhibiting demyelinating and desmyelinating diseases
    Patent number: 5434166
    Abstract: A method of inhibiting demyelinating or dysmyelinating diseases or their symptoms comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, --CH.sub.3, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
    Type: Grant
    Filed: August 22, 1994
    Date of Patent: July 18, 1995
    Assignee: Eli Lilly and Company
    Inventor: Andrew L. Glasebrook