Patents by Inventor Andrew Lawrence Darrow

Andrew Lawrence Darrow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human PRSS11-like S2 serine protease and uses thereof
    Patent number: 7452708
    Abstract: A novel human cDNA, termed PRSS11-L, was isolated which encodes a polypeptide that belongs to the S2/HtrA serine protease family. The PRSS11-L mRNA is widely expressed in several tissues throughout the body by multi-tissue Northern blotting. The full-length PRSS11-L cDNA, was cloned, expressed and purified. Proteolytic activity was demonstrated using the protein substrate casein. The isolated nucleic acid or polypeptide molecule of the invention can be used in detection assays, gene therapy, and screening assays.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: November 18, 2008
    Assignee: Ortho-Mcneil Pharmaceutical, Inc.
    Inventors: Andrew Lawrence Darrow, Jian-Shen Qi, Cailin Chen, Patricia Andrade-Gordon
  • Human PRSS11-Like S2 serine protease and uses thereof
    Patent number: 7132523
    Abstract: A novel human nucleic acid and polypeptide, termed PRSS11-L, are disclosed. PRSS11-L, which is observed in tissues throughout the body, can be used in methods of detection, gene therapy, and screening.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: November 7, 2006
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Andrew Lawrence Darrow, Jian-shen Qi, Cailin Chen, Patricia Andrade-Gordon
  • Human PRSS11-like S2 serine protease and uses thereof
    Publication number: 20040005659
    Abstract: A novel human cDNA, termed PRSS11-L, was isolated which encodes a polypeptide that belongs to the S2/HtrA serine protease family. The PRSS11-L mRNA is widely expressed in several tissues throughout the body by multi-tissue Northern blotting. The full-length PRSS11-L cDNA, was cloned, expressed and purified. Proteolytic activity was demonstrated using the protein substrate casein. The isolated nucleic acid or polypeptide molecule of the invention can be used in detection assays, gene therapy, and screening assays.
    Type: Application
    Filed: July 3, 2002
    Publication date: January 8, 2004
    Inventors: Andrew Lawrence Darrow, Jian-Shen Ql, Cailin Chen, Patricia Andrade-Gordon