Abstract: Described are systems, devices, and methods which related to various aspects of assays for detecting and/or determining a measure of the concentration of analyte molecules or particles in a sample fluid. In some cases, the systems employ an assay consumable comprising a plurality of assay sites. The systems, devices, and/or methods, in some cases, are automated. In some cases, the systems, devices, and/or methods relate to inserting a plurality of beads into assay sites, sealing assay sites, imaging assay sites, or the like.

Abstract: A portable, self-contained beverage apparatus includes a container assembly having a known storage capacity for storing a consumable liquid, and a dispensing assembly disposed within the container assembly that dispenses variable, non-zero quantities of additives into the consumable liquid. The dispensing assembly includes multiple apertures structured and arranged to retain vessels containing the additives to be dispensed into the consumable liquid. The beverage apparatus also includes a level sensor disposed within the container assembly that determines a consumable liquid level of the consumable liquid stored in the container assembly. In certain embodiments, one or more positive displacement pumping mechanisms are configured to pump additive liquid from additive containers into a beverage chamber.

Abstract: An all-linkage mechanism for a seating unit is provided that allows the ottoman to be extended between a closed position and an extended position, with the top face of the ottoman facing upwardly during the entire motion. The mechanism is motorized, and may be stopped in a position intermediate the closed and extended positions, such as a laptop position. The mechanism is compact, allowing use on a high-leg, wood-to-the-floor seating unit.

Abstract: Provided herein is a method for sequence analysis that comprises analyzing PCR reactions that each contain different portions of the same sample, wherein at least some of the primer pairs are in more than one PCR reaction and at least one of the PCR reactions contains some but not all of the primer pairs of the other reaction(s).

Abstract: A vacuum cleaner including a vacuum motor configured to draw an air flow through an air flow path of the vacuum cleaner; a dirt separator having dirt, receptacle; a display screen; and a controller configured to control images displayed on the screen. The dirt receptacle has a closed configuration in which it can receive dirt separated from the air flow, and an open configuration in which dirt contained in the dirt receptacle can be emptied therefrom. The controller is configured to display video instructions on the screen.

Abstract: A computer-implemented method of computer-implemented method of perceiving structure in a point cloud comprises: applying clustering to the point cloud, and thereby identifying at least one moving object cluster within the point cloud, the point cloud comprising time-stamped points captured over a non-zero accumulation window; determining a motion model for the moving object cluster, by fitting one or more parameters of the motion model to the time-stamped points of that cluster; using the motion model to transform the time-stamped points of the moving object cluster to a common reference time; and applying a perception component to the transformed points of the moving object cluster to extract information about structure exhibited in the transformed points.

Abstract: A method for the analysis of minimal residual disease is provided. In some embodiments, the method comprises obtaining multiple pairs of primers designed to amplify sequences that contain a plurality of sequence variations that have been previously identified in a patient's tumor. Amplicons are then obtained through a targeted multiplex amplification that amplifies those sequences from cell-free DNA isolated from a plasma sample. The amplicons are sequenced and two or more of the sequence variations are detected from sequence reads, wherein the detecting comprises comparing a quantity of sequence reads containing a sequence variation against a threshold value. A score is then calculated for the patient sample based on the combined allele frequencies of the detected two or more sequence variations, wherein the score indicates the presence of minimal residual disease.

Abstract: Provided herein is a method for sequence analysis that comprises analyzing PCR reactions that each contain different portions of the same sample, wherein at least some of the primer pairs are in more than one PCR reaction and at least one of the PCR reactions contains some but not all of the primer pairs of the other reaction(s).

Abstract: Provided herein is a method for sequence analysis that comprises analyzing PCR reactions that each contain different portions of the same sample, wherein at least some of the primer pairs are in more than one PCR reaction and at least one of the PCR reactions contains some but not all of the primer pairs of the other reaction(s).

Abstract: Technologies for synchronizing content items across cloud systems are provided. An example method can include receiving, by a first content management system (CMS), authentication information associated with a second CMS; based on the authentication information, establishing a communication channel between the first CMS and second CMS; using the communication channel, providing a user interface identifying collections of content items stored on the second CMS; receiving, by the first CMS, a request to create a first collection of content items based on a second collection of content items selected by a user account from the user interface, the second collection being stored on the second CMS; creating, by the first CMS, the first collection in association with the user account; populating the first collection with placeholders corresponding to content items in the second collection; and upon detecting a change to the second collection, updating the first collection to reflect the change.

Abstract: Technologies for synchronizing content items across cloud systems are provided. An example method can include receiving, by a first content management system (CMS), authentication information associated with a second CMS; based on the authentication information, establishing a communication channel between the first CMS and second CMS; using the communication channel, providing a user interface identifying collections of content items stored on the second CMS; receiving, by the first CMS, a request to create a first collection of content items based on a second collection of content items selected by a user account from the user interface, the second collection being stored on the second CMS; creating, by the first CMS, the first collection in association with the user account; populating the first collection with placeholders corresponding to content items in the second collection; and upon detecting a change to the second collection, updating the first collection to reflect the change.

Abstract: Provided herein is a method for sequence analysis that comprises analyzing PCR reactions that each contain different portions of the same sample, wherein at least some of the primer pairs are in more than one PCR reaction and at least one of the PCR reactions contains some but not all of the primer pairs of the other reaction(s).

Abstract: A load-bearing apparatus (100) comprises a winch apparatus (110), and a load-bearing spoolable medium (120) for connecting to a load, the load-bearing spoolable medium comprising a plurality of load-bearing elements (121-123); wherein at least a portion of the load-bearing spoolable medium is spooled about the winch apparatus. The provision of multiple load-bearing elements may help reduce the diameter appropriate for the winch apparatus, while maintaining the necessary load bearing capacity for supporting, paying in and/or paying out the load. The load-bearing apparatus may comprise a tension control apparatus (151-153) for controlling, applying and/or adjusting the tension of the load-bearing spoolable medium.

Abstract: A friction-braking apparatus for a transportation system, having at least one caliper, at least one piston structured and arranged to move the at least one caliper; and at least one brake pad arranged on the at least one caliper. The at least one caliper is structured and arranged to selectively move the at least one brake pad into engagement with at least one rail of the transportation system.

Abstract: A load-bearing apparatus (100) comprises a winch apparatus (110), and a load-bearing spoolable medium (120) for connecting to a load, the load-bearing spoolable medium comprising a plurality of load-bearing elements (121-123); wherein at least a portion of the load-bearing spoolable medium is spooled about the winch apparatus. The provision of multiple load-bearing elements may help reduce the diameter appropriate for the winch apparatus, while maintaining the necessary load bearing capacity for supporting, paying in and/or paying out the load. The load-bearing apparatus may comprise a tension control apparatus (151-153) for controlling, applying and/or adjusting the tension of the load-bearing spoolable medium.

Abstract: A winch apparatus (10) comprises first and second drum assemblies (12, 14) each defining a discontinuous drum contact surface for engaging a common spoolable medium (50), wherein the first and second drum assemblies (12, 14) are configured to rotate about respective first and second axes of rotation (24, 26) which are inclined relative to each other. In one disclosed embodiment the drum assemblies (12, 14) are intermeshed in a general axial direction.

Abstract: A sulfate process for producing titania from a titaniferous material (as herein defined) including a step of leaching said titaniferous material with a leachant to form a process solution that includes an acidic solution of titanyl sulfate and iron sulfate, wherein said sulfate process further includes a filtration step comprising filtering said leachant to at least substantially remove titanyl sulfate particles from said leachant prior to supplying said leachant to said leach step.

Abstract: A winch apparatus (10) comprises first and second drum assemblies (12, 14) each defining a discontinuous drum contact surface for engaging a common spoolable medium (50), wherein the first and second drum assemblies (12, 14) are configured to rotate about respective first and second axes of rotation (24, 26) which are inclined relative to each other. In one disclosed embodiment the drum assemblies (12, 14) are intermeshed in a general axial direction.

Abstract: A sulfate process for producing titania from a titaniferous material (as herein defined) including a step of leaching said titaniferous material with a leachant to form a process solution that includes an acidic solution of titanyl sulfate and iron sulfate, wherein said sulfate process further includes a filtration step comprising filtering said leachant to at least substantially remove titanyl sulfate particles from said leachant prior to supplying said leachant to said leach step.

Abstract: A sulfate process for producing titania from a titaniferous material as disclosed. The process is characterized by a particular leach step for leaching titaniferous material.