Abstract: Disclosed herein, inter alia, are compositions and methods of use thereof for detecting polynucleotides from and within cells and tissues.

Abstract: A void occlusion device that includes a scaffold defining a plurality of voids and a reinforcement member is described. The scaffold is configured to permit the infiltration of human tissue into the plurality of voids. The reinforcement member extends through at least a portion of the scaffold and is configured to resist compressive forces exerted on the scaffold. Also described are embodiments where the void occlusion device is biocompatible, bioresorbable, elastic, and suitable for radio imaging.

Abstract: A computer-implemented method of perceiving structure in a radar point cloud comprises: generating a discretised image representation of the radar point cloud having (i) an occupancy channel indicating whether or not each pixel of the discretised image representation corresponds to a point in the radar point cloud and (ii) a Doppler channel containing, for each occupied pixel, a Doppler velocity of the corresponding point in the radar point cloud; and inputting the discretised image representation to a machine learning (ML) perception component, which has been trained extract information about structure exhibited in the radar point cloud from the occupancy and Doppler channels.

Abstract: Provided herein is a method for sequence analysis that comprises analyzing PCR reactions that each contain different portions of the same sample, wherein at least some of the primer pairs are in more than one PCR reaction and at least one of the PCR reactions contains some but not all of the primer pairs of the other reaction(s).

Abstract: A computer-implemented method of computer-implemented method of perceiving structure in a point cloud comprises: applying clustering to the point cloud, and thereby identifying at least one moving object cluster within the point cloud, the point cloud comprising time-stamped points captured over a non-zero accumulation window; determining a motion model for the moving object cluster, by fitting one or more parameters of the motion model to the time-stamped points of that cluster; using the motion model to transform the time-stamped points of the moving object cluster to a common reference time; and applying a perception component to the transformed points of the moving object cluster to extract information about structure exhibited in the transformed points.

Abstract: A method for the analysis of minimal residual disease is provided. In some embodiments, the method comprises obtaining multiple pairs of primers designed to amplify sequences that contain a plurality of sequence variations that have been previously identified in a patient's tumor. Amplicons are then obtained through a targeted multiplex amplification that amplifies those sequences from cell-free DNA isolated from a plasma sample. The amplicons are sequenced and two or more of the sequence variations are detected from sequence reads, wherein the detecting comprises comparing a quantity of sequence reads containing a sequence variation against a threshold value. A score is then calculated for the patient sample based on the combined allele frequencies of the detected two or more sequence variations, wherein the score indicates the presence of minimal residual disease.

Abstract: Provided herein is a method for sequence analysis that comprises analyzing PCR reactions that each contain different portions of the same sample, wherein at least some of the primer pairs are in more than one PCR reaction and at least one of the PCR reactions contains some but not all of the primer pairs of the other reaction(s).

Abstract: Provided herein is a method for sequence analysis that comprises analyzing PCR reactions that each contain different portions of the same sample, wherein at least some of the primer pairs are in more than one PCR reaction and at least one of the PCR reactions contains some but not all of the primer pairs of the other reaction(s).

Abstract: Technologies for synchronizing content items across cloud systems are provided. An example method can include receiving, by a first content management system (CMS), authentication information associated with a second CMS; based on the authentication information, establishing a communication channel between the first CMS and second CMS; using the communication channel, providing a user interface identifying collections of content items stored on the second CMS; receiving, by the first CMS, a request to create a first collection of content items based on a second collection of content items selected by a user account from the user interface, the second collection being stored on the second CMS; creating, by the first CMS, the first collection in association with the user account; populating the first collection with placeholders corresponding to content items in the second collection; and upon detecting a change to the second collection, updating the first collection to reflect the change.

Abstract: Technologies for synchronizing content items across cloud systems are provided. An example method can include receiving, by a first content management system (CMS), authentication information associated with a second CMS; based on the authentication information, establishing a communication channel between the first CMS and second CMS; using the communication channel, providing a user interface identifying collections of content items stored on the second CMS; receiving, by the first CMS, a request to create a first collection of content items based on a second collection of content items selected by a user account from the user interface, the second collection being stored on the second CMS; creating, by the first CMS, the first collection in association with the user account; populating the first collection with placeholders corresponding to content items in the second collection; and upon detecting a change to the second collection, updating the first collection to reflect the change.

Abstract: Provided herein is a method for sequence analysis that comprises analyzing PCR reactions that each contain different portions of the same sample, wherein at least some of the primer pairs are in more than one PCR reaction and at least one of the PCR reactions contains some but not all of the primer pairs of the other reaction(s).

Abstract: A load-bearing apparatus (100) comprises a winch apparatus (110), and a load-bearing spoolable medium (120) for connecting to a load, the load-bearing spoolable medium comprising a plurality of load-bearing elements (121-123); wherein at least a portion of the load-bearing spoolable medium is spooled about the winch apparatus. The provision of multiple load-bearing elements may help reduce the diameter appropriate for the winch apparatus, while maintaining the necessary load bearing capacity for supporting, paying in and/or paying out the load. The load-bearing apparatus may comprise a tension control apparatus (151-153) for controlling, applying and/or adjusting the tension of the load-bearing spoolable medium.

Abstract: A friction-braking apparatus for a transportation system, having at least one caliper, at least one piston structured and arranged to move the at least one caliper; and at least one brake pad arranged on the at least one caliper. The at least one caliper is structured and arranged to selectively move the at least one brake pad into engagement with at least one rail of the transportation system.

Abstract: A load-bearing apparatus (100) comprises a winch apparatus (110), and a load-bearing spoolable medium (120) for connecting to a load, the load-bearing spoolable medium comprising a plurality of load-bearing elements (121-123); wherein at least a portion of the load-bearing spoolable medium is spooled about the winch apparatus. The provision of multiple load-bearing elements may help reduce the diameter appropriate for the winch apparatus, while maintaining the necessary load bearing capacity for supporting, paying in and/or paying out the load. The load-bearing apparatus may comprise a tension control apparatus (151-153) for controlling, applying and/or adjusting the tension of the load-bearing spoolable medium.

Abstract: A winch apparatus (10) comprises first and second drum assemblies (12, 14) each defining a discontinuous drum contact surface for engaging a common spoolable medium (50), wherein the first and second drum assemblies (12, 14) are configured to rotate about respective first and second axes of rotation (24, 26) which are inclined relative to each other. In one disclosed embodiment the drum assemblies (12, 14) are intermeshed in a general axial direction.

Abstract: A sulfate process for producing titania from a titaniferous material (as herein defined) including a step of leaching said titaniferous material with a leachant to form a process solution that includes an acidic solution of titanyl sulfate and iron sulfate, wherein said sulfate process further includes a filtration step comprising filtering said leachant to at least substantially remove titanyl sulfate particles from said leachant prior to supplying said leachant to said leach step.

Abstract: A winch apparatus (10) comprises first and second drum assemblies (12, 14) each defining a discontinuous drum contact surface for engaging a common spoolable medium (50), wherein the first and second drum assemblies (12, 14) are configured to rotate about respective first and second axes of rotation (24, 26) which are inclined relative to each other. In one disclosed embodiment the drum assemblies (12, 14) are intermeshed in a general axial direction.

Abstract: A sulfate process for producing titania from a titaniferous material (as herein defined) including a step of leaching said titaniferous material with a leachant to form a process solution that includes an acidic solution of titanyl sulfate and iron sulfate, wherein said sulfate process further includes a filtration step comprising filtering said leachant to at least substantially remove titanyl sulfate particles from said leachant prior to supplying said leachant to said leach step.

Abstract: A sulfate process for producing titania from a titaniferous material as disclosed. The process is characterized by a particular leach step for leaching titaniferous material.

Abstract: A guide assembly for sawing an elongate member accurately to length to form the sides of a picture frame comprises two saw-guide units which are adjustably clamped to two guide roads by means of screws. The picture frame glass is placed between reference surfaces of blocks on the saw-guide units to determine the required distance apart of the two saw-guide units. Each saw-guide unit has two pairs of posts defining slots therebetween for the blade of a saw, to hold the saw-blade accurately at 45.degree. to the direction of elongation of the wooden member, for the eventual formation of mitred joints between the sides of the picture frame. Each saw-guide unit includes a special ridge to abut that surface of the wooden member which is to surround the edge of the glass.