Patents by Inventor Andrew M. Brugger

Andrew M. Brugger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030134887
    Abstract: There is provided a method of rapidly relieving pain in a mammalian, preferably human, subject. The method comprises orally administering to the subject an effective pain-relieving amount of a composition comprising celecoxib formulated in such a way as to provide, when tested in fasting humans in accordance with standard pharmacokinetic practice, a blood plasma concentration profile of celecoxib in which a concentration of about 250 ng/ml is attained not later than about 30 minutes after oral administration.
    Type: Application
    Filed: December 27, 2002
    Publication date: July 17, 2003
    Inventors: Aziz Karim, Andrew M. Brugger, Ping Gao, Fred Hassan, James C. Forbes
  • Patent number: 6579895
    Abstract: There is provided a method of rapidly relieving pain in a mammalian, preferably human, subject. The method comprises orally administering to the subject an effective pain-relieving amount of a composition comprising celecoxib formulated in such a way as to provide, when tested in fasting humans in accordance with standard pharmacokinetic practice, a blood plasma concentration profile of celecoxib in which a concentration of about 250 ng/ml is attained not later than about 30 minutes after oral administration.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: June 17, 2003
    Assignee: Pharmacia Corporation
    Inventors: Aziz Karim, Andrew M. Brugger, Ping Gao, Fred Hassan, James C. Forbes
  • Publication number: 20030105144
    Abstract: An orally deliverable pharmaceutical composition is provided comprising an aminosulfonyl-comprising drug, for example a selective cyclooxygenase-2 inhibitory drug such as celecoxib, and a solvent liquid comprising a polyethylene glycol and one or more free radical-scavenging antioxidants. At least a substantial part of the drug is in dissolved form in the solvent liquid. The composition has rapid-onset properties and is useful in treatment of cyclooxygenase-2 mediated conditions and disorders.
    Type: Application
    Filed: April 9, 2002
    Publication date: June 5, 2003
    Inventors: Ping Gao, Tiehua Huang, Russell H. Robins, Juliane M. Bauer, Jane E. Guido, Andrew M. Brugger, Aziz Karim, Fred Hassan, James C. Forbes
  • Publication number: 20020028238
    Abstract: There is provided a method of rapidly relieving pain in a mammalian, preferably human, subject. The method comprises orally administering to the subject an effective pain-relieving amount of a composition comprising celecoxib formulated in such a way as to provide, when tested in fasting humans in accordance with standard pharmacokinetic practice, a blood plasma concentration profile of celecoxib in which a concentration of about 250 ng/ml is attained not later than about 30 minutes after oral administration.
    Type: Application
    Filed: May 25, 2001
    Publication date: March 7, 2002
    Inventors: Aziz Karim, Andrew M. Brugger, Ping Gao, Fred Hassan, James C. Forbes