Patents by Inventor Andrew M. Cigan
Andrew M. Cigan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6399856Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.Type: GrantFiled: November 19, 1998Date of Patent: June 4, 2002Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 6281348Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.Type: GrantFiled: March 17, 1997Date of Patent: August 28, 2001Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 6248935Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.Type: GrantFiled: November 28, 1997Date of Patent: June 19, 2001Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 6072102Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.Type: GrantFiled: November 28, 1997Date of Patent: June 6, 2000Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 5837851Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.Type: GrantFiled: June 7, 1995Date of Patent: November 17, 1998Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 5795753Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.Type: GrantFiled: June 7, 1995Date of Patent: August 18, 1998Assignee: Pioneer Hi-Bred International Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 5792853Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.Type: GrantFiled: June 7, 1995Date of Patent: August 11, 1998Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 5763243Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.Type: GrantFiled: June 7, 1995Date of Patent: June 9, 1998Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 5760190Abstract: A family of genes has been found in plants, said genes encoding a family of developmental proteins that have homologous structures to the mammalian QM genes. Recombinant molecules which include the QM genes in plants are useful to transform cells and regenerate plants that, as a result, have altered developmental pathways. Methods of producing male sterile plants use recombinant molecules containing either the QM sense genes or antesense genes with appropriate promoters.Type: GrantFiled: June 7, 1995Date of Patent: June 2, 1998Assignee: Pioneer Hi-Bred International, Inc.Inventors: John Neill, Dorothy A. Pierce, Andrew M. Cigan
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Patent number: 5750868Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and structural genes capable of acting in a cascading fashion to produce a reversible effect on a plant phenotype. A first genetic construct comprising (i) an operator that is capable of controlling expression of a dominant negative gene, (ii) a dominant negative gene that, when expressed in a plant disrupts pollen formation or function, (iii) a tissue specific promoter that regulates the expression of a gene encoding a DNA-binding protein which binds to the operator and activates transcription, and (iv) a gene encoding a DNA binding region and an activating domain, causes male sterility in a plant. In particular, the present invention relates to the use of a DAM-methylase gene as a dominant negative gene and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene.Type: GrantFiled: December 8, 1994Date of Patent: May 12, 1998Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 5728817Abstract: A family of genes has been found in plants, said genes encoding a family of developmental proteins that have homologous structures to the mammalian QM genes. Recombinant molecules which include the QM genes in plants are useful to transform cells and regenerate plants that, as a result, have altered developmental pathways. Methods of producing male sterile plants use recombinant molecules containing either the QM sense genes or antesense genes with appropriate promoters.Type: GrantFiled: June 7, 1995Date of Patent: March 17, 1998Assignee: Pioneer Hi-Bred International, Inc.Inventors: John Neill, Dorothy A. Pierce, Andrew M. Cigan
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Patent number: 5689049Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant male-sterile. In particular, the present invention relates to the use of an anther-specific promoter, designated 5126, and its operable linkage to a dominant negative gene, more particularly an exogenous methylase gene or DAM methylase gene, to achieve male sterility.Type: GrantFiled: June 7, 1995Date of Patent: November 18, 1997Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 5689051Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant male-sterile. In particular, the present invention relates to an isolated DNA molecule comprising an anther-specific promoter, designated 5126, its operable linkage to a DNA sequence encoding a gene product and transgenic plants comprising said DNA. More particularly the gene product linked to promoter 5126 disrupts the function or formation of pollen.Type: GrantFiled: June 7, 1995Date of Patent: November 18, 1997Assignee: Pioneer Hi-Bred International, Inc.Inventors: Andrew M. Cigan, Marc C. Albertsen
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Patent number: 5583210Abstract: A family of genes has been found in plants, said genes encoding a family of developmental proteins that have homologous structures to the mammalian QM genes. Recombinant molecules which include the QM genes in plants are useful to transform cells and regenerate plants that, as a result, have altered developmental pathways. Methods of producing male sterile plants use recombinant molecules containing either the QM sense genes or antesense genes with appropriate promoters.Type: GrantFiled: March 18, 1993Date of Patent: December 10, 1996Assignee: Pioneer Hi-Bred International, Inc.Inventors: John Neill, Dorothy A. Pierce, Andrew M. Cigan