Patents by Inventor Andrew M. Cigan

Andrew M. Cigan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6399856
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.
    Type: Grant
    Filed: November 19, 1998
    Date of Patent: June 4, 2002
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 6281348
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.
    Type: Grant
    Filed: March 17, 1997
    Date of Patent: August 28, 2001
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 6248935
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.
    Type: Grant
    Filed: November 28, 1997
    Date of Patent: June 19, 2001
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 6072102
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.
    Type: Grant
    Filed: November 28, 1997
    Date of Patent: June 6, 2000
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 5837851
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 17, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 5795753
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 18, 1998
    Assignee: Pioneer Hi-Bred International Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 5792853
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 11, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 5763243
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant reversibly male-sterile. In particular, the present invention relates to the use of dominant negative genes and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene. The invention also relates to novel DNA sequences which exhibit the ability to serve as anther-specific promoters in plants.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 9, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 5760190
    Abstract: A family of genes has been found in plants, said genes encoding a family of developmental proteins that have homologous structures to the mammalian QM genes. Recombinant molecules which include the QM genes in plants are useful to transform cells and regenerate plants that, as a result, have altered developmental pathways. Methods of producing male sterile plants use recombinant molecules containing either the QM sense genes or antesense genes with appropriate promoters.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 2, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: John Neill, Dorothy A. Pierce, Andrew M. Cigan
  • Patent number: 5750868
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and structural genes capable of acting in a cascading fashion to produce a reversible effect on a plant phenotype. A first genetic construct comprising (i) an operator that is capable of controlling expression of a dominant negative gene, (ii) a dominant negative gene that, when expressed in a plant disrupts pollen formation or function, (iii) a tissue specific promoter that regulates the expression of a gene encoding a DNA-binding protein which binds to the operator and activates transcription, and (iv) a gene encoding a DNA binding region and an activating domain, causes male sterility in a plant. In particular, the present invention relates to the use of a DAM-methylase gene as a dominant negative gene and an anther-specific promoter. Male sterility is reversed by incorporation into a plant of a second genetic construct which represses the dominant negative gene.
    Type: Grant
    Filed: December 8, 1994
    Date of Patent: May 12, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 5728817
    Abstract: A family of genes has been found in plants, said genes encoding a family of developmental proteins that have homologous structures to the mammalian QM genes. Recombinant molecules which include the QM genes in plants are useful to transform cells and regenerate plants that, as a result, have altered developmental pathways. Methods of producing male sterile plants use recombinant molecules containing either the QM sense genes or antesense genes with appropriate promoters.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: March 17, 1998
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: John Neill, Dorothy A. Pierce, Andrew M. Cigan
  • Patent number: 5689049
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant male-sterile. In particular, the present invention relates to the use of an anther-specific promoter, designated 5126, and its operable linkage to a dominant negative gene, more particularly an exogenous methylase gene or DAM methylase gene, to achieve male sterility.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 18, 1997
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 5689051
    Abstract: Plant development can be altered by transforming a plant with a genetic construct that includes regulatory elements and DNA sequences capable of acting in a fashion to inhibit pollen formation or function, thus rendering the transformed plant male-sterile. In particular, the present invention relates to an isolated DNA molecule comprising an anther-specific promoter, designated 5126, its operable linkage to a DNA sequence encoding a gene product and transgenic plants comprising said DNA. More particularly the gene product linked to promoter 5126 disrupts the function or formation of pollen.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: November 18, 1997
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Andrew M. Cigan, Marc C. Albertsen
  • Patent number: 5583210
    Abstract: A family of genes has been found in plants, said genes encoding a family of developmental proteins that have homologous structures to the mammalian QM genes. Recombinant molecules which include the QM genes in plants are useful to transform cells and regenerate plants that, as a result, have altered developmental pathways. Methods of producing male sterile plants use recombinant molecules containing either the QM sense genes or antesense genes with appropriate promoters.
    Type: Grant
    Filed: March 18, 1993
    Date of Patent: December 10, 1996
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: John Neill, Dorothy A. Pierce, Andrew M. Cigan