Abstract: The present application relates to plasma cells and plasma cell precursors that express a macromolecule, such as a protein, protein mimetic or a peptide and compositions comprising these plasma cells or plasma cell precursors. The application further relates to methods of using and making the plasma cells and plasma cell precursors that express the macromolecule. Methods of treatment comprising administering the plasma cells or plasma cell precursors are also contemplated.

Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: A transaction system enables a portable token to co-operate with a fixed terminal. The token is inductively coupled to the terminal, and receives data from the terminal via a frequency modulated carrier signal. Data is sent from the token to the terminal by amplitude modulation of the carrier signal from the terminal, i.e. by modulating the power drawn by the token from the terminal. The power needed to energize the on-board processing capability of the token is also obtained from the terminal via the inductive coupling. The token includes an arrangement for commencing processor operation in an orderly manner when it is brought into the proximity of a terminal, and for providing an orderly shut down when the token is withdrawn.

Abstract: A transaction system enables a portable token to co-operate with a fixed terminal. The token is inductively coupled to the terminal, and receives data from the terminal via a frequency modulated carrier signal. Data is sent from the token to the terminal by amplitude modulation of the carrier signal from the terminal, i.e. by modulating the power driven by the token from the terminal. The power needed to energize the on-board processing capability of the token is also obtained from the terminal via the inductive coupling. The token includes an arrangement for commencing processor operation in an orderly manner when it is brought into the proximity of the terminal, and for providing an orderly shut down when the token is withdrawn.