Abstract: The present embodiments provide methods, compounds, and compositions for treating, preventing, or ameliorating a disease associated with dysregulation of the complement alternative pathway by administering a Complement Factor B (CFB) specific inhibitor to a subject.

Abstract: An apparatus and methods for deploying, recovering, and servicing an AUV are disclosed. The apparatus includes a linelatch system that is made up of a tether management system connected to a flying latch vehicle by a tether. The linelatch system can be connected to a surface vessel by an umbilical on one end and to an AUV on the other end. In addition to providing a mechanical connection, between the AUV and a surface vessel, the linelatch system can also carry power and data between the surface vessel (i.e., through the umbilical) and the AUV.

Abstract: An underwater apparatus for performing subsurface operations adapted to be operated from a remote location above the surface of a body of water is disclosed. The apparatus includes a linelatch system that is made up of a tether management system connected to a flying latch vehicle by a tether. The tether management system controls the amount of free tether between itself and the flying latch vehicle. The flying latch vehicle interfaces with various underwater structures. Also disclosed are methods for recovering, deploying, and relaying power to a subsurface vehicle using the linelatch system.

Abstract: An underwater apparatus for performing subsurface operations adapted to be operated from a remote location above the surface of a body of water is disclosed. The apparatus includes a linelatch system that is made up of a tether management system connected to a flying latch vehicle by a tether. The tether management system controls the amount of free tether between itself and the flying latch vehicle. The flying latch vehicle interfaces with various underwater structures. Also disclosed are methods of transferring power and/or data between two or more underwater devices using the linelatch system of the invention.

Abstract: An apparatus and methods for deploying, recovering, and servicing an AUV are disclosed. The apparatus includes a linelatch system that is made up of a tether management system connected to a flying latch vehicle by a tether. The linelatch system can be connected to a surface vessel by an umbilical on one end and to an AUV on the other end. In addition to providing a mechanical connection, between the AUV and a surface vessel, the linelatch system can also carry power and data between the surface vessel (i.e., through the umbilical) and the AUV.

Abstract: An underwater apparatus for performing subsurface operations adapted to be operated from a remote location above the surface of a body of water is disclosed. The apparatus includes a underwater vehicle that is made up of a tether management system connected to a detachable flying craft by a tether. The tether management system controls the amount of free tether between itself and the detachable flying craft. The detachable flying craft interfaces with various underwater structures. Also disclosed are methods of transferring power and/or data between two or more underwater devices using the underwater vehicle of the invention.

Abstract: A support system for supporting an underwater work platform includes a work platform submerged in a body of water and a support structure supported by the body of water above the work platform. The work platform is supported by a plurality of cables connected between the support structure and the work platform. Motions of the support structure in the body of water are sensed, and the length of the cables is adjusted in response to the sensed motions of the support structure so that the work platform can be maintained stationary even when the support structure is subjected to wave forces and currents.