Patents by Inventor Andrew Maksymowych

Andrew Maksymowych has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for transepithelial molecular transport
    Publication number: 20090053248
    Abstract: The invention relates to fragments of Clostridium botulinum HC that can be linked with an entity (e.g., an antigen, a particle, or a radionuclide) and used to deliver the entity across a non-keratinized epithelial membrane of an animal. The fragments are useful, for example, for making vaccines, antidotes, and anti-toxins and in situations in which rapid uptake of an agent by an animal is desired.
    Type: Application
    Filed: March 25, 2008
    Publication date: February 26, 2009
    Applicant: Thomas Jefferson University
    Inventors: Lance Simpson, Andrew Maksymowych, Jong-Beak Park
  • Compositions and methods for transepithelial molecular transport
    Publication number: 20040013687
    Abstract: The invention relates to fragments of Clostridium botulinum HC that can be linked with an entity (e.g., an antigen, a particle, or a radionuclide) and used to deliver the entity across a non-keratinized epithelial membrane of an animal. The fragments are useful, for example, for making vaccines, antidotes, and anti-toxins and in situations in which rapid uptake of an agent by an animal is desired.
    Type: Application
    Filed: June 2, 2003
    Publication date: January 22, 2004
    Applicant: Thomas Jefferson University
    Inventors: Lance Simpson, Andrew Maksymowych, Jung-Beak Park
  • Compositions and methods for systemic delivery of oral vaccines and therapeutic agents
    Patent number: 6051239
    Abstract: Compositions and methods of oral delivery of an antigen or therapeutic agent to the general circulation using a modified botulinum toxin which is capable of translocating from the gut to the general circulation but which is altered to be nontoxic are provided.
    Type: Grant
    Filed: October 20, 1997
    Date of Patent: April 18, 2000
    Assignee: Thomas Jefferson University
    Inventors: Lance Simpson, Nikita Kiyatkin, Andrew Maksymowych