Abstract: A vehicle control system and method includes a first controller that controls operation of a first vehicle and is operably coupled with a first communication system. A second controller controls operation of a second vehicle and is operably coupled with a second communication system. The first controller determines an orientation of the second vehicle and identifies a type of the second vehicle. The first controller generates a first set of vehicle control signals based on the orientation and the type of the second vehicle. The first communication system communicates the first set of vehicle control signals with the second communication system. The first controller overrides control of the second vehicle by the second controller to control operation of the first vehicle and the second vehicle according to the first set of vehicle control signals.

Abstract: Apparatus for sorting articles includes a conveyor having a plurality of article support members, each article support member provided to extend longitudinally parallel to a direction of movement of the conveyor, the support members being provided spaced 5 transversely across a conveyor and being pivotable at a first end about a transverse axis to unload the article from the conveyor.

Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: The present invention relates to systems and methods for removing and recovering precious metals, such as platinum-group metals (PGMs), including palladium, from wastewater and waste streams. The invention also relates to systems and methods for recycling the recovered precious metals for catalytic applications.

Abstract: A protective equipment includes a rotatable window and an extended member secured to a peripheral edge of the rotatable window. The rotatable window may be configured as a shield to be disposed between a patient and a healthcare worker to minimize exposure of the healthcare worker to at least one of the patient's bodily fluids, bacteria, and viruses. A port provides entrance by one or more instruments through the rotatable window or the extended member, thereby providing access to the patient while protecting the healthcare worker from the patient's bodily fluids, bacteria and/or viruses. The protective equipment may include an air flow system configured to receive and filter air expelled by the patient, to pull the expelled air away from the patient's face and to filter/clean the expelled air.

Abstract: A traction system is provided for a rail draft vehicle including an engine with a driveshaft, at least a pair of rubber-tired traction wheels, and at least one rail guide wheel pressurized relative to the vehicle by at least one fluid-powered cylinder. Included in the system are a programmable processor connected to a driveshaft speed sensor, a rail guide wheel speed sensor, an engine throttle controller, a fluid-powered cylinder controller and a vehicle control panel. The processor is constructed and arranged for automatically adjusting the engine throttle controller in coordination with the fluid-powered cylinder controller for achieving movement of the rail draft vehicle from a dead stop position by increasing applied vehicle weight upon the traction wheels by the at least one fluid-powered cylinder and adjusting engine RPM's until the vehicle begins movement as detected by the rail guide wheel speed sensor.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: The present invention relates to systems and methods for removing and recovering precious metals, such as platinum-group metals (PGMs), including palladium, from wastewater and waste streams. The invention also relates to systems and methods for recycling the recovered precious metals for catalytic applications.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Disclosed is a system for identifying and tracking items using unique product identifiers. In some embodiments, the system includes a central unit and an external unit. The central unit is coupled to the external unit. The external unit includes a plurality of products. The central unit is configured to generate a plurality of unique product identifiers (IDs). The central unit is further configured to authorize the external unit to access the plurality of unique IDs. Upon authorizing, the central unit accesses the plurality of unique IDs and assigns each of the plurality of unique IDs to a product of a plurality of products.

Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Abstract: A traction system is provided for a rail draft vehicle including an engine with a driveshaft, at least a pair of rubber-tired traction wheels, and at least one rail guide wheel pressurized relative to the vehicle by at least one fluid-powered cylinder. Included in the system are a programmable processor connected to a driveshaft speed sensor, a rail guide wheel speed sensor, an engine throttle controller, a fluid-powered cylinder controller and a vehicle control panel. The processor is constructed and arranged for automatically adjusting the engine throttle controller in coordination with the fluid-powered cylinder controller for achieving movement of the rail draft vehicle from a dead stop position by increasing applied vehicle weight upon the traction wheels by the at least one fluid-powered cylinder and adjusting engine RPM's until the vehicle begins movement as detected by the rail guide wheel speed sensor.

Abstract: Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.