Patents by Inventor Andrew Mark Davidoff

Andrew Mark Davidoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of detecting tumors containing complexes of p53 and HSP70
    Patent number: 5652115
    Abstract: The present invention relates to the finding that the class of mutant p53 proteins which bind to HSP70 defines a group of mutant p53 proteins which elicit serum autoantibodies. Thus, disclosed is a method of classifying tumor cells for the ability to produce serum p53 autoantibodies in a patient carrying such tumor cells, a method of detecting tumor cells containing a mutant p53 protein capable of forming a complex with a 70 kilodalton heat shock protein (hsp70) in the cells in a patient, a method of distinguishing tumor cells capable of causing more aggressive disease in a patient carrying the tumor cells, and a method of monitoring a patient for the recurrence of disease in a patient previously diagnosed as carrying tumor cells.
    Type: Grant
    Filed: July 18, 1994
    Date of Patent: July 29, 1997
    Assignee: Duke University
    Inventors: Jeffrey Robert Marks, James Dirk Inglehart, Andrew Mark Davidoff, Jerry G. Henslee