Patents by Inventor Andrew Mark SETTLES

Andrew Mark SETTLES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mitigation of maize heat stress with recombinant 6-phosphogluconate dehydrogenase
    Patent number: 11761012
    Abstract: The disclosure relates to modification of a heat resistant cytoplasmic heat stable 6-phosphogluconate dehydrogenase (6PGDH) enzyme by fusing the cytoplasmic 6PGDH enzyme in frame to a plastid-targeting sequence. This modification allows the import of the cytoplasmic 6PGDH enzyme into plastids of a plant cell. Polynucleotides encoding and expressing the modified cytoplasmic 6PGDH enzymes are provided. The disclosure further provides transgenic plants and seeds containing the disclosed polynucleotides and expressing the modified cytoplasmic 6PGDH enzymes during development. The invention further relates to methods for developing a transgenic plant that has increased heat resistance and yield during heat stress.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: September 19, 2023
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
    Inventors: Andrew Mark Settles, Camila Ribeiro
  • MITIGATION OF MAIZE HEAT STRESS WITH RECOMBINANT 6-PHOSPHOGLUCONATE DEHYDROGENASE
    Publication number: 20200392527
    Abstract: The disclosure relates to modification of a heat resistant cytoplasmic heat stable 6-phosphogluconate dehydrogenase (6PGDH) enzyme by fusing the cytoplasmic 6PGDH enzyme in frame to a plastid-targeting sequence. This modification allows the import of the cytoplasmic 6PGDH enzyme into plastids of a plant cell. Polynucleotides encoding and expressing the modified cytoplasmic 6PGDH enzymes are provided. The disclosure further provides transgenic plants and seeds containing the disclosed polynucleotides and expressing the modified cytoplasmic 6PGDH enzymes during development. The invention further relates to methods for developing a transgenic plant that has increased heat resistance and yield during heat stress.
    Type: Application
    Filed: November 5, 2018
    Publication date: December 17, 2020
    Inventors: Andrew Mark SETTLES, Camila RIBEIRO