Abstract: A method of targeting, which involves capturing a first video of a scene about a potential targeting coordinate by a first video sensor on a first aircraft; transmitting the first video and associated potential targeting coordinate by the first aircraft; receiving the first video on a first display in communication with a processor, the processor also receiving the potential targeting coordinate; selecting the potential targeting coordinate to be an actual targeting coordinate for a second aircraft in response to viewing the first video on the first display; and guiding a second aircraft toward the actual targeting coordinate; where positive identification of a target corresponding to the actual targeting coordinate is maintained from selection of the actual targeting coordinate.

Abstract: Provided herein are agents, compositions, and methods useful for animal health, e.g., for altering the level, activity, or metabolism of one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the alteration resulting in a decrease in the fitness of the host. The invention features a composition that includes an agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the agents described herein may be used to decrease the fitness of a variety of insects that carry vector-borne pathogens that cause disease in animals.

Abstract: A method, apparatus, and program for additive manufacturing. The additive manufacturing device includes a positioning mechanism configured to provide independent movement of at least one build unit in at least two dimensions. The build unit may further include a gasflow device for providing a flow zone along a first direction with relation to the build unit. The build unit may further include a powder delivery mechanism and an irradiation beam directing unit. The irradiation bean unit may follow a first irradiation path, wherein the first irradiation path forms at least a first solidification line and at least a second solidification line formed at an angle other than 0° and 180° with respect to the first solidification line. During the formation of the first solidification line, the build unit may be positioned in a first orientation such that the first direction of the flow zone is substantially perpendicular to the first solidification line.

Abstract: The invention relates to a breathing assistance apparatus that may be configured to reduce the risk of damage to electronics within the apparatus as a result of liquid leaks within the apparatus or impacts to the apparatus. In other forms, the apparatus may be configured to allow for easy assembly and/or safe operation.

Abstract: Flight control systems, flight control methods, and aircraft are provided. An aircraft including a system and a method for receiving, via a fuel switch, a first control signal indicative of an off position on a fuel switch, determining a throttle resolver angle of a throttle controller in response to the first control signal, comparing the throttle resolver angle to a threshold throttle angle, and generating a pilot warning in response to the first control signal and the throttle resolver angle exceeding the threshold throttle angle.

Abstract: The invention relates to compositions, methods, devices, systems, and kits for detecting and characterizing molecules using a nanopore device.

Abstract: A humidification chamber (24, 50, 300, 400, 500, 600 or 700) for humidifying gases is provided comprising: a water tub that is configured to receive a volume of water; a gases inlet for receiving a flow of gases into an interior volume of the humidification chamber; and a gases outlet through which a humidified flow of gases may exit the interior volume of the humidification chamber. One or more fill apertures (120) are provided in fluid communication with the water tub such that the water tub can be filled with water through the one or more fill apertures. A sealing closure (850) is also provided and configured to be releaseably mounted on the humidification chamber (24, 50, 300, 400, 500, 600 or 700), the sealing closure (850) being configured to sealingly close each fill aperture (120) when the sealing closure (850) is mounted on the humidification chamber to resist gas and/or vapour escaping from the one or more fill apertures (120).

Abstract: A computing system can receive sensor data from one or more computing devices co-located with a vehicle, where the sensor data indicates a seating arrangement of one or more current passengers of the vehicle. The system can receive location data from the one or more computing devices co-located with the vehicle, and using the sensor data and the location data, the system determines a first route for the vehicle to travel to a start location of a requesting user such that a curbside seat of the vehicle is available for the requesting user. The system then transmits navigation instructions to the one or more computing devices co-located with the vehicle to provide routing directions corresponding to the first route.

Abstract: A method, apparatus, and program for additive manufacturing. The additive manufacturing device includes a positioning mechanism configured to provide independent movement of at least one build unit in at least two dimensions. The build unit may further include a gasflow device for providing a flow zone along a first direction with relation to the build unit. The build unit may further include a powder delivery mechanism and an irradiation beam directing unit. The irradiation bean unit may follow a first irradiation path, wherein the first irradiation path forms at least a first solidification line and at least a second solidification line formed at an angle other than 0° and 180° with respect to the first solidification line. During the formation of the first solidification line, the build unit may be positioned in a first orientation such that the first direction of the flow zone is substantially perpendicular to the first solidification line.

Abstract: Provided herein are methods and compositions useful for human health, e.g., for targeting one or more microorganisms resident in a host insect (e.g., arthropod, e.g., insect, e.g., pathogen vector), the modulation resulting in a decrease in the fitness of the host. The invention features a composition that includes a modulating agent (e.g., phage, peptide, small molecule, antibiotic, or combinations thereof) that can alter the host's microbiota in a manner that is detrimental to the host. By disrupting microbial levels, microbial activity, microbial metabolism, or microbial diversity, the modulating agent described herein may be used to decrease the fitness of a variety of insects that carry vector-home pathogens that cause disease in humans.

Abstract: A method of targeting, which involves capturing a first video of a scene about a potential targeting coordinate by a first video sensor on a first aircraft; transmitting the first video and associated potential targeting coordinate by the first aircraft; receiving the first video on a first display in communication with a processor, the processor also receiving the potential targeting coordinate; selecting the potential targeting coordinate to be an actual targeting coordinate for a second aircraft in response to viewing the first video on the first display; and guiding a second aircraft toward the actual targeting coordinate; where positive identification of a target corresponding to the actual targeting coordinate is maintained from selection of the actual targeting coordinate.

Abstract: A patient interface is configured to treat sleep disordered breathing of a patient and includes a frame having a central bore configured to connect to an elbow, a cushion supported on the frame and defining a breathing chamber configured to receive the pressurized gas, and a headgear assembly configured to support the frame and the cushion on the patient's face, the headgear assembly comprising a pair of Y-shaped front straps and a pair of Y-shaped rigidizers attached to a respective one of the pair of Y-shaped front straps. Each Y-shaped rigidizer is connected to the frame and adds rigidity to the respective one of the pair of Y-shaped front straps, and each Y-shaped front strap and each Y-shaped rigidizer has a respective top end extending away from an intersection of the Y and is configured to extend along the patient's temple region, in use.

Abstract: A system provides ultra-wideband (UWB) positioning. The system exchanges ranging signals at a first rate between a UWB beacon and a UWB tag. The system then determines movement or location information of the UWB tag; and select, based on the movement or location information, a second rate for exchanging subsequent ranging signals between the UWB beacon and the UWB tag. The system then exchanges the subsequent ranging signals at the second rate between the UWB beacon and the UWB tag.

Abstract: An electrical connector includes a shell and a coupling ring. The shell has contact receiving passages and an outer wall with a coupling ring retaining projection. The coupling ring is integrally mounted on the shell. The coupling ring is movable between a first position and a second position. A spring is integrally positioned on the coupling ring. The spring is provided in a stressed position when the coupling ring is moved to the second position. Openings are provided in the coupling ring; the openings being positioned proximate the spring. The opening are dimensioned to allow the removal of residual material produced during the manufacture of the electrical connector.

Abstract: Disclosed herein are plant-modifying compositions including a plurality of plant messenger packs (PMPs) (e.g., including a plant extracellular vesicle (EV), or segment, portion, or extract thereof), wherein the PMPs include a plant-modifying agent, and wherein the plant-modifying agent comprising the heterologous RNA. The compositions herein are useful in methods for modifying plants such as to increase plant fitness, wherein the increase in plant fitness comprising an increase in development, growth, yield, resistance to abiotic stressors, or resistance to biotic stressors.

Abstract: A garment for providing circulatory-related disorder therapy includes a skin contacting layer, a backing layer, and a coupling. The backing layer is coupled to the skin contacting layer such that the skin contacting layer and the backing layer form a plurality of macro-chambers. A first one of the plurality of macro-chambers is partitioned into a plurality of micro-chambers. Each of the plurality of micro-chambers is in direct fluid communication with at least one other of the plurality of micro-chambers. The coupling is coupled to the backing layer and is configured to supply pressurized air directly into the first macro-chamber such that the pressurized air is delivered to a first one of the plurality of micro-chambers of the first macro-chamber.

Abstract: TOOL TRACKING A system for determining the location of a toolpiece, wherein: the toolpiece is carried by a tool and the tool comprises an imaging device for capturing images of the environment around the tool; and the system comprises an image processor communicatively coupled to the imaging device for receiving images therefrom and having access to one or more reference images of an expected environment, the image processor being configured to compare an image captured by the imaging device with at least one reference image to identify a match therebetween and to determine in dependence on characteristics of that match the location of the toolpiece.

Abstract: Systems and methods are described herein to grow a layered structure. The layered structure is implemented as a VCSEL and comprises a first germanium substrate layer having a first lattice constant, a second layer that has a second lattice constant and is epitaxially grown over the first germanium substrate layer, wherein the second layer comprises a compound of a first constituent and a second constituent, and a third layer that has a third lattice constant and is epitaxially grown over the second layer, wherein the third layer comprises a compound of a third constituent and a fourth constituent, wherein the first, second, third and fourth constituents are selected such that the layered structure is pseudomorphic and the first lattice constant is between the second lattice constant and the third lattice constant.

Abstract: A breathing assistance apparatus that comprises a housing with inner and outer walls and an upper surface, wherein the walls and upper surface are integrally formed as a single part to avoid seams or joins between the walls to reduce the risk of damage to electronics within the apparatus as a result of liquid leaks. Also disclosed is a control system for a heating element of a humidifier which provides a secondary or back up protection mechanism to disable power to the heating element if a first electronic protection circuit does not cause the first switching member to disable power to the heating element.