Abstract: Systems and methods are disclosed for identifying points-of-interest using customized query prediction. According to certain embodiments, a partial query is received from a client via a network. The partial query may comprise a plurality of characters associated with a full query and location data associated with the client. The received partial query may be analyzed using at least one dictionary. Based on the analysis of the received partial query, at least one query may be predicted. Moreover, at least one point-of-interest may be identified based on the at least one predicted query. Further, data associated with the at least one identified point-of-interest may be transmitted over the network to the client prior to receiving the full query from the client.

Abstract: A method and system for making financial or medical decisions. The method comprises training sets of models using classification training with sets of data derived from segregated data sources. Overall weighting of each model within the sets of models are determined for each of the sub-datasets. The sets of models, the overall weighting of each model and a number of examples provided from the data for each of the datasets are transmitted to a central server over a communication network, wherein the central server is configured to determine the relative weights of each of the sets of models in the overall ensemble model based on the number of examples, combine the sets of models, receive new application data, and predict at least one of outcome variables, an uncertainty factor for the variables, and drivers of the outcome variables based on the new application data.

Abstract: Systems and methods in accordance with embodiments of the invention implement modular array cameras using sub-array modules. In one embodiment, an X×Y sub-array module includes: an X×Y arrangement of focal planes, where X and Y are each greater than or equal to 1; and an X×Y arrangement of lens stacks, the X×Y arrangement of lens stacks being disposed relative to the X×Y arrangement of focal planes so as to form an X×Y arrangement of cameras, where each lens stack has a field of view that is shifted with respect to the field-of-views of each other lens stack so that each shift includes a sub-pixel shifted view of the scene; and image data output circuitry that is configured to output image data from the X×Y sub-array module that can be aggregated with image data from other sub-array modules so that an image of the scene can be constructed.

Abstract: Systems and methods in accordance with embodiments of the invention implement one-dimensional array cameras, as well as modular array cameras using sub-array modules. In one embodiment, a 1×N array camera module includes: a 1×N arrangement of focal planes, where N is greater than or equal to 2, each focal plane includes a plurality of rows of pixels that also form a plurality of columns of pixels, and each focal plane not including pixels from another focal plane; and a 1×N arrangement of lens stacks, the arrangement of lens stacks being disposed relative to the arrangement of focal planes so as to form a 1×N arrangement of cameras, each configured to independently capture an image of a scene, where each lens stack has a field of view that is shifted with respect to that of each other lens stack so that each shift includes a sub-pixel shifted view of the scene.

Abstract: Systems and methods for controlling the parameters of groups of focal planes as focal plane groups in an array camera are described. One embodiment includes a plurality of focal planes, and control circuitry configured to control the capture of image data by the pixels within the focal planes. In addition, the control circuitry includes: a plurality of parameter registers, where a given parameter register is associated with one of the focal planes and contains configuration data for the associated focal plane; and a focal plane group register that contains data identifying focal planes that belong to a focal plane group. Furthermore, the control circuitry is configured to control the imaging parameters of the focal planes in the focal plane groups by mapping instructions that address virtual register addresses to the addresses of the parameter registers associated with focal planes within specific focal plane groups.

Abstract: Systems and methods for detecting defective camera arrays, optic arrays and/or sensors are described. One embodiment includes capturing image data using a camera array; dividing the captured images into a plurality of corresponding image regions; identifying the presence of localized defects in any of the cameras by evaluating the image regions in the captured images; and detecting a defective camera array using the image processing system when the number of localized defects in a specific set of image regions exceeds a predetermined threshold, where the specific set of image regions is formed by: a common corresponding image region from at least a subset of the captured images; and any additional image region in a given image that contains at least one pixel located within a predetermined maximum parallax shift distance along an epipolar line from a pixel within said common corresponding image region within the given image.

Abstract: Systems and methods in accordance with embodiments of the invention actively align a lens stack array with an array of focal planes to construct an array camera module. In one embodiment, a method for actively aligning a lens stack array with a sensor that has a focal plane array includes: aligning the lens stack array relative to the sensor in an initial position; varying the spatial relationship between the lens stack array and the sensor; capturing images of a known target that has a region of interest using a plurality of active focal planes at different spatial relationships; scoring the images based on the extent to which the region of interest is focused in the images; selecting a spatial relationship between the lens stack array and the sensor based on a comparison of the scores; and forming an array camera subassembly based on the selected spatial relationship.

Abstract: Provided are methods of diagnosing and treating vascular disorders of the CNS or disorders of the blood-brain barrier comprising the use of Wnt ligands involved in the canonical Wnt signaling pathway.

Abstract: A method of encoding and decoding languages for international communication. A set of core words may be encoded, although the full vocabulary of the language might also be covered. The result is particularly suitable for use by people in relation to the keypad of a mobile phone, but may also be implemented in translation or communication software to create a language database for example. The encoding includes assigning digital symbols to selected words in the language, assigning alphanumeric representations to the digital symbols, and assigning pronounceable elements to the alphanumeric representations.

Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.

Abstract: A method of reducing noise in a digital image produced by a digital imaging device, includes producing a luminance and at least one chrominance channel from a full-color digital image with each channel having a plurality of pixels and each such pixel has a value; producing an edge value from neighboring pixels in neighborhoods in the at least one chrominance channel; modifying the pixel value in the chrominance channel with an infinite impulse response filter responsive to the edge value of the corresponding pixel neighborhood to provide a modified chrominance channel; and producing a full-color digital image from the luminance channel and the modified chrominance channel, with reduced noise.

Abstract: The present invention concerns the discovery of a new family of hedgehog binding proteins, referred to herein as “hedgehog interacting proteins” or “HIPs”, which are demonstrated to bind to hedgehog polypeptides with high affinity. As described herein, the vertebrate HIP proteins exhibit spatially and temporally restricted expression domains indicative of important roles in hedgehog-mediated induction.

Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.

Abstract: The present invention concerns the discovery that proteins encoded by a family of vertebrate genes, termed here hedgehog-related genes, comprise morphogenic signals produced by embryonic patterning centers, and are involved in the formation of ordered spatial arrangements of differentiated tissues in vertebrates. The present invention makes available compositions and methods that can be utilized, for example to generate and/or maintain an array of different vertebrate tissue both in vitro and in vivo.