Patents by Inventor Andrew Mesecar

Andrew Mesecar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20240124395
    Abstract: Inhibitors of SARS-COV-2 (COVID), pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
    Type: Application
    Filed: October 23, 2023
    Publication date: April 18, 2024
    Inventors: Arun K. Ghosh, Monika Yadav, Andrew Mesecar
  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20240116865
    Abstract: Inhibitors of SARS-CoV-2 (COVID), pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
    Type: Application
    Filed: November 8, 2023
    Publication date: April 11, 2024
    Inventors: Arun K. Ghosh, Monika Yadav, Andrew Mesecar
  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20240101541
    Abstract: Bis-amide inhibitors of SARS-CoV-2 (COVID) and methods of using them to treat a severe acute respiratory syndrome.
    Type: Application
    Filed: November 30, 2021
    Publication date: March 28, 2024
    Applicant: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Andrew Mesecar, Hiroaki Mitsuya
  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20240043417
    Abstract: Bis-amide inhibitors of SARS-CoV-2 (COVID) and methods of using them to treat a severe acute respiratory syndrome.
    Type: Application
    Filed: November 30, 2021
    Publication date: February 8, 2024
    Applicant: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Hiroaki Mitsuya, Andrew Mesecar
  • Compounds for the treatment of SARS
    Patent number: 11834408
    Abstract: Inhibitors of SARS-CoV-2 (COVID), pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
    Type: Grant
    Filed: May 26, 2022
    Date of Patent: December 5, 2023
    Assignee: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Monika Yadav, Andrew Mesecar
  • Compounds for the treatment of SARS
    Patent number: 11795159
    Abstract: Bis-amide inhibitors of SARS-CoV-2 (COVID); pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: October 24, 2023
    Assignee: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Hiroaki Mitsuya, Andrew Mesecar, Dana Shahabi
  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20230192671
    Abstract: Bis-amide inhibitors of SARS-CoV-2 (COVID); pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
    Type: Application
    Filed: March 15, 2021
    Publication date: June 22, 2023
    Inventors: Arun K. Ghosh, Hiroaki Mitsuya, Andrew Mesecar
  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20230159516
    Abstract: Bis-amide inhibitors of SARS-CoV-2 (COVID), pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
    Type: Application
    Filed: February 23, 2021
    Publication date: May 25, 2023
    Inventors: Arun K. Ghosh, Hiroaki Mitsuya, Monika Yadav, Andrew Mesecar
  • 6-amino-2,4-dihydropyrano [2,3-c] pyrazoles and methods of use
    Patent number: 11617738
    Abstract: The present invention generally relates to 6-amino-2,4-dihydropyrano [2,3-c] pyrazoles as a ubiquitin specific protease 7 (USP7) inhibitor useful for the treatment of diseases mediated by malfunction of USP7, such as inflammation, cancer, and immunological disorders. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases mediated by malfunction of USP7, in mammals using compounds disclosed herein.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: April 4, 2023
    Assignee: Purdue Research Foundation
    Inventors: Antonella Pepe, Andrew Mesecar
  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20220411401
    Abstract: Bis-amide inhibitors of SARS-CoV-2 (COVID); pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
    Type: Application
    Filed: May 23, 2022
    Publication date: December 29, 2022
    Inventors: Arun K. Ghosh, Hiroaki Mitsuya, Andrew Mesecar, Dana Shahabi
  • COMPOUNDS FOR THE TREATMENT OF SARS
    Publication number: 20220396550
    Abstract: Inhibitors of SARS-CoV-2 (COVID), pharmaceutical compositions comprising same; and methods of treating a severe acute respiratory syndrome.
    Type: Application
    Filed: May 26, 2022
    Publication date: December 15, 2022
    Inventors: Arun K. Ghosh, Monika Yadav, Andrew Mesecar
  • BACE1 INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20220389030
    Abstract: Described herein are compounds of the formulae (I)-(III) as well as pharmaceutical compositions comprising such compounds and methods for using such compounds/pharmaceutical compositions for treating Alzheimer's disease.
    Type: Application
    Filed: January 3, 2022
    Publication date: December 8, 2022
    Inventors: Arun K. Ghosh, Andrew Mesecar, Margherita Brindisi, Emilio Leal Cardenas
  • BACE1 inhibitors for the treatment of Alzheimer's disease
    Patent number: 11214579
    Abstract: Described herein are compounds of the formulae (I)-(III) as well as pharmaceutical compositions comprising such compounds and methods for using such compounds/pharmaceutical compositions for treating Alzheimer's disease.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: January 4, 2022
    Assignee: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Andrew Mesecar, Margherita Brindisi, Emilio Leal Cardenas
  • 6-AMINO-2,4-DIHYDROPYRANO [2,3-C] PYRAZOLES AND METHODS OF USE
    Publication number: 20210196684
    Abstract: The present invention generally relates to 6-amino-2,4-dihydropyrano[2,3-c] pyrazoles as a ubiquitin specific protease 7 (USP7) inhibitor useful for the treatment of diseases mediated by malfunction of USP7, such as inflammation, cancer, and immunological disorders. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases mediated by malfunction of USP7, in mammals using compounds disclosed herein.
    Type: Application
    Filed: March 12, 2021
    Publication date: July 1, 2021
    Applicant: Purdue Research Foundation
    Inventors: Antonella Pepe, Andrew Mesecar
  • 6-amino-2,4-dihydropyrano [2,3-c] pyrazoles and methods of use
    Patent number: 10980781
    Abstract: The present invention generally relates to 6-amino-2,4-dihydropyrano [2,3-c] pyrazoles as a ubiquitin specific protease 7(USP7) inhibitor useful for the treatment of diseases mediated by malfunction of USP7, such as inflammation, cancer, and immunological disorders. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases mediated by malfunction of USP7, in mammals using compounds disclosed herein.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: April 20, 2021
    Assignee: Purdue Research Foundation
    Inventors: Antonella Pepe, Andrew Mesecar
  • BACE1 INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20200299308
    Abstract: Described herein are compounds of the formulae (I)-(III) as well as pharmaceutical compositions comprising such compounds and methods for using such compounds/pharmaceutical compositions for treating Alzheimer's disease.
    Type: Application
    Filed: October 12, 2018
    Publication date: September 24, 2020
    Inventors: Arun K. Ghosh, Andrew Mesecar, Margherita Brindisi, Emilio Leal Cardenas
  • 6-AMINO-2,4-DIHYDROPYRANO [2,3-C] PYRAZOLES AND METHODS OF USE
    Publication number: 20200078336
    Abstract: The present invention generally relates to 6-amino-2,4-dihydropyrano [2,3-c] pyrazoles as a ubiquitin specific protease 7 (USP7) inhibitor useful for the treatment of diseases mediated by malfunction of USP7, such as inflammation, cancer, and immunological disorders. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases mediated by malfunction of USP7, in mammals using compounds disclosed herein.
    Type: Application
    Filed: March 29, 2018
    Publication date: March 12, 2020
    Applicant: Purdue Research Foundation
    Inventors: Antonella Pepe, Andrew Mesecar