Abstract: The present disclosure provides a medicament delivery device for accommodating a medicament container. The device comprises a distal cap, a plunger rod, a signal member having a distal base and a plurality of arms extending proximally therefrom along the plunger rod, a drive spring extending at least partially into an interior of the plunger rod, the drive spring having a proximal end abutting against a proximal end bottom of the plunger rod and a distal end abutting against the distal base of the signal member. The signal member, the plunger rod and the biasing member are at least partially accommodated in a cavity of the distal cap, said cavity being open towards proximally. In an initial state the drive spring is compressed and there is a gap between the distal base of the signal member and a distal end wall of the cavity.

Abstract: Methods and kits are provided for inducing disassembly of intermediate filaments (IFs) in cells or tissues. In some embodiments, a method comprises expressing in, or introducing into, a cell or tissue a fusion protein comprising a self-labeling protein derived from a haloalkane dehalogenase and an IF-targeting protein that either incorporates into IF polymers or binds specifically to IF proteins; administering a rhodamine- or fluorescein-derived photosensitizer modified with a ligand that specifically binds to the self-labeling protein to associate the photosensitizer with the IF; and administering light under conditions effective to activate the photosensitizer and induce IF disassembly. Kits are also provided that comprise at least one vector encoding a fusion protein comprising a self-labeling protein derived from a haloalkane dehalogenase and an IF-targeting protein, and a rhodamine- or fluorescein-derived photosensitizer modified with a ligand that specifically binds to the self-labeling protein.

Abstract: A processing device retrieves a clerical-based security policy and a configuration-based security policy associated with a network, wherein the clerical-based security policy corresponds to the configuration-based security policy. The processing device prompts a generative artificial intelligence model to translate the configuration-based security policy from a structured data format to a plain text description, wherein the prompting indicates an operation of a security component associated with the configuration-based security policy. The processing device prompts the generative AI model to compare the clerical-based security policy and the plain text description of the configuration-based security. The processing device receive a response from the generative AI model, the response comprising an indication of a discrepancy between the clerical-based security policy and the configuration-based security.

Abstract: Systems and methods for comparing and aligning clerical and configurational security policies are described. Methods include retrieving a clerical-based security policy and a configuration-based security policy associated with a network, generating a comparison prompt to a generative artificial intelligence (AI) model comprising a request to compare the clerical-based security policy and the configuration-based security policy, providing the comparison prompt to the generative AI model; and receiving a response from the generative AI model comprising indications of discrepancies between the clerical-based security policy and the configuration-based security policy.

Abstract: A system including: one or more processors; a memory storing instructions that, when executed by the one or more processors are configured to cause the system to: receive a plurality of user names and a plurality of anonymized user identifiers; receive a plurality of user attributes associated with one or more users of the plurality of users; receive a first plurality of hash values that uniquely identify an association between each user attribute and one or more users; receive a first request for a listing of user names associated with a first user attribute; receive a first secret key; generate a second plurality of hash values; determine a first subset of the first plurality of hash values that match the second plurality of hash values; generate a first graphical user interface including the listing of user names; and transmit the first graphical user interface to the first user device.

Abstract: A system including: one or more processors; a memory storing instructions that, when executed by the one or more processors are configured to cause the system to: receive a plurality of user names and a plurality of anonymized user identifiers; receive a plurality of user attributes associated with one or more users of the plurality of users; receive a first plurality of hash values that uniquely identify an association between each user attribute and one or more users; receive a first request for a listing of user names associated with a first user attribute; receive a first secret key; generate a second plurality of hash values; determine a first subset of the first plurality of hash values that match the second plurality of hash values; generate a first graphical user interface including the listing of user names; and transmit the first graphical user interface to the first user device.

Abstract: Integrated circuit structures having contacts for uniform grid metal gate and trench contact cut are described. A structure includes a dielectric sidewall spacer between a gate electrode and a conductive trench contact. A dielectric cut plug structure extends through the gate electrode, through the dielectric sidewall spacer, and through the conductive trench contact. A dielectric cap layer covers the dielectric sidewall spacer and the dielectric cut plug structure, and exposes a portion of the gate electrode and a portion of the conductive trench contact. A conductive via is in contact with the portion of the gate electrode or the portion of the conductive trench contact. The conductive via overlaps a top surface of the dielectric cap layer.

Abstract: A fitting for use with metal, corrugated tubing having peaks and valleys includes a nut configured to receive the tubing; a sealing member for placement in a valley of the tubing, the sealing member including a sealing surface; an adaptor configured to engage the nut, the adaptor including an adaptor sealing surface; and an anti-tamper sleeve configured to encompass the nut and adaptor; wherein upon assembly, the tubing is compressed between the adaptor sealing surface and the sealing surface.

Abstract: Selective dielectric growth directing contact to gate or contact to trench contact are described. In an example, an integrated circuit structure includes a plurality of gate structures above a substrate. A plurality of conductive trench contact structures is alternating with the plurality of gate structures and have an uppermost surface above an uppermost surface of gate electrodes of the plurality of gate structures. The integrated circuit structure also includes a plurality of dielectric spacers, a corresponding one of the plurality of dielectric spacers between adjacent ones of the plurality of gate structures and the plurality of conductive trench contact structures. A dielectric-on-metal (DOM) layer is on and is confined to the uppermost surface of the conductive trench contact structures. A gate contact via is on a gate electrode of one of the plurality of gate structures.

Abstract: Provided are example systems for dissipating heat from vehicle-based data processing components. In an example implementation, a heat dissipation device includes a heat sink, an enclosure configured to receive a device including electronic circuitry, a fan, and a flange extending along a periphery of the enclosure and/or the heat sink. The heat dissipation device is configured for insertion into an aperture of a wall of an interior compartment of a vehicle, such that the flange is positioned against the wall, at least a portion of the enclosure is positioned within the interior compartment of the vehicle, and at least a portion of the heat sink and the fan are positioned along an exterior of the vehicle.

Abstract: A drone with capability to passively deliver a payload to a delivery site. The drone is an unmanned aerial system that includes a container suspended below a main body of the system by way of at least one line. The container may interface a surface at the delivery site to passively deliver the payload. This may be achieved through a passive delivery mechanism that includes one of an actuator to trigger the passive delivery or a container guide for tipping the container upon the interfacing with the surface of the site.

Abstract: A system including: one or more processors; a memory storing instructions that, when executed by the one or more processors are configured to cause the system to: receive a plurality of user names and a plurality of anonymized user identifiers; receive a plurality of user attributes associated with one or more users of the plurality of users; receive a first plurality of hash values that uniquely identify an association between each user attribute and one or more users; receive a first request for a listing of user names associated with a first user attribute; receive a first secret key; generate a second plurality of hash values; determine a first subset of the first plurality of hash values that match the second plurality of hash values; generate a first graphical user interface including the listing of user names; and transmit the first graphical user interface to the first user device.

Abstract: The present disclosure relates to a cap assembly for a medicament delivery device. The cap assembly comprises: a cap body arranged to be mounted to a proximal end of a medicament delivery device for protecting and for removing a medicament delivery member shield. The cap body has an inner cap structure defining a channel extending along the central axis of the cap body, and a gripping member configured to be received in the channel. The gripping member is radially flexible and has a first leg, a second leg, and a connecting portion extending between the first leg and the second leg. The first leg and the second leg each has a proximal portion that is radially flexible and extends distally from the connecting portion. Each proximal portion has an inclined section extending radially inwards in an axial direction away from the connecting portion.

Abstract: A system including: one or more processors; a memory storing instructions that, when executed by the one or more processors are configured to cause the system to: receive a plurality of user names and a plurality of anonymized user identifiers; receive a plurality of user attributes associated with one or more users of the plurality of users; receive a first plurality of hash values that uniquely identify an association between each user attribute and one or more users; receive a first request for a listing of user names associated with a first user attribute; receive a first secret key; generate a second plurality of hash values; determine a first subset of the first plurality of hash values that match the second plurality of hash values; generate a first graphical user interface including the listing of user names; and transmit the first graphical user interface to the first user device.

Abstract: A system including: one or more processors; a memory storing instructions that, when executed by the one or more processors are configured to cause the system to: receive a plurality of user names and a plurality of anonymized user identifiers; receive a plurality of user attributes associated with one or more users of the plurality of users; receive a first plurality of hash values that uniquely identify an association between each user attribute and one or more users; receive a first request for a listing of user names associated with a first user attribute; receive a first secret key; generate a second plurality of hash values; determine a first subset of the first plurality of hash values that match the second plurality of hash values; generate a first graphical user interface including the listing of user names; and transmit the first graphical user interface to the first user device.

Abstract: Provided are example systems for dissipating heat from vehicle-based data processing components. In an example implementation, a heat dissipation device includes a heat sink, an enclosure configured to receive a device including electronic circuitry, a fan, and a flange extending along a periphery of the enclosure and/or the heat sink. The heat dissipation device is configured for insertion into an aperture of a wall of an interior compartment of a vehicle, such that the flange is positioned against the wall, at least a portion of the enclosure is positioned within the interior compartment of the vehicle, and at least a portion of the heat sink and the fan are positioned along an exterior of the vehicle.

Abstract: The present disclosure relates to a cap assembly for a medicament delivery device. The cap assembly comprises: a cap body arranged to be mounted to a proximal end of a medicament delivery device for protecting and for removing a medicament delivery member shield. The cap body has an inner cap structure defining a channel extending along the central axis of the cap body, and a gripping member configured to be received in the channel. The gripping member is radially flexible and has a first leg, a second leg, and a connecting portion extending between the first leg and the second leg. The first leg and the second leg each has a proximal portion that is radially flexible and extends distally from the connecting portion. Each proximal portion has an inclined section extending radially inwards in an axial direction away from the connecting portion.

Abstract: The present disclosure relates to a cap assembly for a medicament delivery device. The cap assembly comprises: a cap body arranged to be mounted to a proximal end of a medicament delivery device for protecting and for removing a medicament delivery member shield. The cap body has an inner cap structure defining a channel extending along the central axis of the cap body, and a gripping member configured to be received in the channel. The gripping member is radially flexible and has a first leg, a second leg, and a connecting portion extending between the first leg and the second leg. The first leg and the second leg each has a proximal portion that is radially flexible and extends distally from the connecting portion. Each proximal portion has an inclined section extending radially inwards in an axial direction away from the connecting portion.

Abstract: Exemplary methods and systems may generate a point cloud data generated polyhedral geofence for use in navigating a vehicle. The polyhedral geofence may be generated, or created, from point cloud data such as lidar data. Further, a vehicle may utilize propulsion devices and controllers for moving the vehicle based on a point map data generated polyhedral geofence.