Patents by Inventor Andrew Muddle

Andrew Muddle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrogel particle formulation
    Patent number: 7022313
    Abstract: New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also provided. In addition, methods for administering pharmacologically active agent to a subject are provided. These methods are useful for delivering drugs, biopharmaceuticals, vaccines and diagnostics agents.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: April 4, 2006
    Assignee: PowderJect Research Ltd.
    Inventors: Barbara Horsey O'Connor, Terry Lee Burkoth, Steven Joseph Prestrelski, Yuh-Fun Maa, Andrew Muddle, Roderick Hafner
  • Particle delivery techniques
    Publication number: 20050271733
    Abstract: A method is provided for in vivo or ex vivo delivery of a preparation of powdered nucleic acid molecules into vertebrate tissue for transformation of cells in the tissue using needleless injection techniques. The method can be used to deliver therapeutically relevant nucleotide sequences to cells in mammalian tissue to provide gene therapy, elicit immunity or to provide antisense or ribozyme functions. A method for providing densified processed pharmaceutical compositions is also described. The method is used to convert non-dense pharmaceutical powders or particulate formulations into densified particles optimally suited for transdermal delivery using a needleless syringe. The method is also used to optimize the density and particle size of powders and particulate formulations for subsequent transdermal delivery thereof. Densified pharmaceutical compositions formed by the present methods are also provided.
    Type: Application
    Filed: April 29, 2005
    Publication date: December 8, 2005
    Inventors: Terry Burkoth, David Sarphie, Andrew Muddle, Linda Porter
  • Hydrogel particle formation
    Publication number: 20050191361
    Abstract: New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also provided. In addition, methods for administering pharmacologically active agent to a subject are provided. These methods are useful for delivering drugs, biopharmaceuticals, vaccines and diagnostics agents.
    Type: Application
    Filed: April 11, 2005
    Publication date: September 1, 2005
    Inventors: Barbara O'Connor, Terry Burkoth, Steven Prestrelski, Yuh-Fun Maa, Andrew Muddle, Roderick Hafner
  • Hydrogel particle formulation
    Publication number: 20020061336
    Abstract: New compositions formed from the combination of an active substance with a hydrogel carrier moiety are provided. The compositions are suitable for use in high-velocity transdermal particle injection techniques. Methods of providing the new compositions are also provided. In addition, methods for administering pharmacologically active agent to a subject are provided. These methods are useful for delivering drugs, biopharmaceuticals, vaccines and diagnostics agents.
    Type: Application
    Filed: August 3, 2001
    Publication date: May 23, 2002
    Inventors: Barbara Horsey O'Connor, Terry Lee Burkoth, Steven Joseph Prestrelski, Yuh-Fun Maa, Andrew Muddle, Roderick Hafner