Abstract: A method of plasma etching or plasma deposition of a target layer of material in or onto a sample comprising a further layer of material, the method comprising: during a process of plasma etching or plasma deposition of the target layer of material: directing light of a first wavelength at the sample; measuring the intensity of light of the first wavelength reflected by the sample; directing light of a second wavelength at the sample; and measuring the intensity of light of the second wavelength reflected by the sample; determining, based on the intensities of light reflected by the sample, an endpoint of the process of plasma etching or plasma deposition of the target layer of material; and ending the process of plasma etching or plasma deposition of the target layer of material based on the determined endpoint.

Abstract: The present invention describes novel boron containing pyrazole compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.

Abstract: The present invention relates to compounds of formula (I) which are capable of activating STING (Stimulator of Interferon Genes). The present invention further relates to pharmaceutical compositions comprising at least a compound of formula (I), as well as the use of these compounds or the pharmaceutical compositions as a medicament, e.g., for treating canine or feline cancer, or as vaccine adjuvants.

Abstract: The present invention relates to compounds of formula (I) which are capable of activating STING (Stimulator of Interferon Genes). The present invention further relates to pharmaceutical compositions comprising at least a compound of formula (I), as well as the use of these compounds or the pharmaceutical compositions as a medicament, e.g., for treating canine or feline cancer, or as vaccine adjuvants.

Abstract: The present disclosure describes boron containing pyrimidine compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the present disclosure have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.

Abstract: The present invention describes novel boron containing pyrazole compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.

Abstract: A method of preparing a silicon carbide wafer for subsequent epitaxial growth thereon is disclosed. The method comprises (a) placing the silicon carbide wafer onto a support table in a plasma processing chamber such that the surface of the silicon carbide wafer distal to the support table is unmasked; (b) establishing a flow of an etch gas mixture into the plasma processing chamber, wherein the etch gas mixture comprises molecular hydrogen, H2; and (c) generating a plasma from the etch gas mixture within the plasma processing chamber and using the plasma to etch the unmasked surface of the wafer so as to reduce the roughness of the unmasked surface.

Abstract: Aspects of the present disclosure address systems, methods, and a user interface for providing interactive skew group visualizations for integrated circuit (IC) design. The method includes causing display of a user interface that includes a display of a grouped view of a clock-tree including a plurality of skew group indicators. The method further includes receiving a user selection of a skew group indicator and updating the user interface to display a detailed view of the skew group including a graphical representation of each clock sink in the skew group and corresponding timing information. The method further includes receiving a second user selection of a first clock sink and in response, the display is updated to display an indicator of a physical location of the first clock sink within the clock tree.

Abstract: A gas turbine engine component includes an inner support structure surrounding an engine center axis and fixed to an engine static structure, an outer support structure spaced radially outward of the inner support structure, and a curved beam comprised of a plurality of curved beam spring segments that are positioned adjacent to each other to form a ring. The inner and outer support structures are coupled together around the curved beam to enclose the curved beam therebetween and form an assembly. A bearing is spaced radially inward of the assembly.

Abstract: The present invention describes novel boron containing pyrazole compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus kinase (JAK) inhibitors and are useful in the in the treatment or control of inflammation, auto-immune diseases, cancer, and other disorders and indications where modulation of JAK would be desirable. Also described are methods of treating inflammation, auto-immune diseases, cancer, and other conditions that are susceptible to the inhibition of a Janus kinase by administering a compound herein described.

Abstract: Various embodiments provide for clock network generation for a circuit design using an inverting integrated clock gate (ICG). According to some embodiments, a clock network with one or more inverting ICGs is generated, after a topology of the clock network is defined, by applying a non-inverting ICG-to-inverting ICG transform to one or more nodes of the clock network that comprise a non-inverting ICG. Additionally, according to some embodiments, a clock network is generated bottom-up (from the clock sinks to the root clock signal source) using one or more inverting ICGs.

Abstract: Various embodiments provide for clock network generation for a circuit design using a negative-edge integrated clock gate (ICG). According to some embodiments, a clock network with one or more negative-edge ICGs is generated, after a topology of the clock network is defined, by applying a positive-edge ICG-to-negative-edge ICG transform to one or more nodes of the clock network that comprise a positive-edge ICG. Additionally, according to some embodiments, a clock network is generated bottom-up (from the clock sinks to the root clock signal source) using one or more negative-edge ICGs.

Abstract: A gas turbine engine component includes a bearing configured to support a shaft for rotation about an axis, wherein the bearing includes an outer race and an inner race, and a bearing housing spaced radially outwardly of the outer race. A curved beam centering spring is positioned between the outer race and the bearing housing. A cylindrical wall is radially outward of the bearing housing and engages the outer race and the bearing housing.

Abstract: A gas turbine engine component includes a bearing configured to support a shaft for rotation about an axis, wherein the bearing includes an outer race and an inner race, and a bearing housing spaced radially outwardly of the outer race. A curved beam centering spring is positioned between the outer race and the bearing housing. A cylindrical wall is radially outward of the bearing housing and engages the outer race and the bearing housing.

Abstract: A gas turbine engine component includes a ring comprising a single-piece component having an outer peripheral surface and an inner peripheral surface that surrounds an engine center axis, a plurality of outer diameter pedestals formed in the outer peripheral surface and circumferentially spaced apart from each other, and a plurality of inner diameter pedestals formed in the inner peripheral surface and circumferentially spaced apart from each other. A plurality of recesses are formed in the outer peripheral surface and are circumferentially spaced apart from each other.

Abstract: A gas turbine engine component includes a ring comprising a single-piece component having an outer peripheral surface and an inner peripheral surface that surrounds an engine center axis, a plurality of outer diameter pedestals formed in the outer peripheral surface and circumferentially spaced apart from each other, and a plurality of inner diameter pedestals formed in the inner peripheral surface and circumferentially spaced apart from each other. A plurality of recesses are formed in the outer peripheral surface and are circumferentially spaced apart from each other.

Abstract: A gas turbine engine component includes an inner support structure surrounding an engine center axis and fixed to an engine static structure, an outer support structure spaced radially outward of the inner support structure, and a curved beam comprised of a plurality of curved beam spring segments that are positioned adjacent to each other to form a ring. The inner and outer support structures are coupled together around the curved beam to enclose the curved beam therebetween and form an assembly. A bearing is spaced radially inward of the assembly.

Abstract: Electronic design automation systems, methods, and media are presented for cell cloning during circuit design. In one embodiment, for a circuit design comprising a plurality of flip-flop elements having clock inputs provided by a routing tree, a delay is identified for each flip-flop element. The flip-flop elements are clustered by delay to generate at least two clusters of flip-flop elements. Elements within the clusters are then grouped by physical characteristics to generate delay groups of flip-flop elements. An updated routing tree is then generated for the circuit design using the first delay group and the second delay group.

Abstract: Electronic design automation systems, methods, and media are presented for multi-dimension clock gate design in clock tree synthesis. In one embodiment, an input list of clock gate types is accessed, and the list is then used in generating a clock gate matrix. A circuit design with a clock tree is then accessed. The multi-dimensional design involves automatically selecting, for a first clock gate of the routing tree, a first clock gate type from the clock gate matrix based on a size and associated area for the first clock gate type to select a drive strength value for the first clock gate in the routing tree. The first clock gate is then resized to generate a resized first clock gate using the clock gate matrix to adjust a first delay value associated with the first clock gate while maintaining the drive strength value.

Abstract: Electronic design automation systems, methods, and media are presented for clock gate placement with data path awareness. One embodiment involves accessing a circuit design with a clock tree, clock gates, and an initial movement area. A set of positions for a set of data path connection points associated with the data routing lines are identified, along with an expansion direction from the initial placement position toward the set of positions for the set of data path connection points, and the initial movement is expanded to consider additional placement options for the clock gate based on the data path connection points.