Patents by Inventor Andrew Nickless

Andrew Nickless has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR TREATING HER2-NEGATIVE OR HER2-LOW CANCER
    Publication number: 20240124610
    Abstract: The present disclosure provides methods for treating a subject having a HER2 non-amplified (HER2-negative) cancer or low HER2 expressing (HER2-low) cancer, comprising detecting expression of a BCAR4 gene fusion in a biological sample from the subject. If expression of the BCAR4 gene fusion is detected, a HER2-targeted cancer treatment is administered to the subject; if expression of the BCAR4 gene fusion is not detected, a cancer treatment that is not HER2-targeted is administered to the subject. Methods of predicting response to a HER2-targeted cancer treatment and detecting BCAR4 or BCAR4 gene fusion activation are also provided.
    Type: Application
    Filed: May 16, 2023
    Publication date: April 18, 2024
    Applicant: Washington University
    Inventors: Nicole Maher, Christopher Maher, Andrew Nickless, Jin Zhang, Amy Ly, Jace Webster