Abstract: In one or more embodiments, a software service allows software providers to implement machine learning (ML) features into products offered by the software providers. Each ML feature may be referred to as an encapsulated ML application, which may be defined and maintained in a central repository, while also being provisioned for each user of the software provider on an as-needed basis. Advantageously, embodiments allow for a central definition for an ML application that encapsulates data science and processing capabilities and routines of the software provider. This central ML application delivers a ML deployment pipeline template that may be replicated multiple times as separate, tailored runtime pipeline instances on a per-user basis. Each runtime pipeline instance accounts for differences in the specific data of each user, resulting in user-specific ML models and predictions based on the same central ML application.

Abstract: Compounds of formula (I): (I) and related aspects.

Abstract: A method of power transfer control among a plurality of power sources coupled through a distribution system. The method comprises determining, at each power source of the plurality of power sources, an assignment of priorities for each of the plurality of power sources. The method also comprises obtaining, at each power source, information indicating an availability of each of the plurality of power sources and determining a set of available power sources, and identifying, at each power source, a preferred power source and a standby power source from the plurality of power sources. The method further comprises determining to change the preferred power source from a first power source to a second power source in response to detecting a condition, and conducting the power transfer.

Abstract: Compounds of formula (I): and related aspects.

Abstract: Compounds of formula (I) and related aspects.

Abstract: Compounds of formula (I): (I) and related aspects.

Abstract: Compounds of formula (I) wherein ring B is selected from the group consisting of Formula (B-a) and Formula (B-bc) as human cytidine triphosphate synthase 1 (CTPS 1) inhibitors for the treatment of proliferative diseases, such as e.g. cancer, such as e.g. leukemia and lymphoma, e.g. inflammatory skin diseases such as psoriasis, or e.g. multiple sclerosis. The present description discloses the synthesis and characterisation of exemplary compounds as well as pharmacological data thereof (e.g. page 129 to page 302; examples; biological examples 1 and 2; tables 1-17). Specific examples are e.g.: N-(4-(5-Chloropyridin-3-yl)phenyl)-2-(2-(cyclopropane-sulfonamido) pyrimidin-4-yl)butanamide (Formula P1) or 1-(2-(Cyclopropanesulfonamido)pyrimidin-4-yl)-N-(4-(6-ethoxypyrazin-2-yl)phenyl)cyclopentanecarboxamide (Formula P2).

Abstract: The invention provides a compound of formula (I) and processes for the manufacture of such compounds, related intermediates, compositions comprising such compounds and the use of such compounds as cytidine triphosphate synthase 1 inhibitors, particularly in the treatment or prophylaxis of disorders associated with cell proliferation.

Abstract: The invention provides a compound of formula (I): formula (I) and the use of such compounds as cytidine triphosphate synthase 1 inhibitors, particularly in the treatment or prophylaxis of disorders associated with cell proliferation.

Abstract: Compounds of formula (I) and related aspects.

Abstract: Compounds of formula (I) as human cytidine triphosphate synthase 1 (CTPS1) inhibitors for the treatment of prolifera-tive diseases, such as e.g. cancer, such as e.g. leukemia and lymphoma, e.g. inflammatory skin diseases such as psoriasis, or e.g. multiple sclerosis. The present description discloses the synthesis and characterisa-tion of exemplary compounds as well as pharmacological data thereof (e.g. pages 64 to 80; examples; biological examples 1 and 2; e.g. compounds P140, P231 to P263; tables 1 to 10). Specific examples are e.g.: N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)-4-(2-(methylsulfonami-N do) pyrimidin-4-yl)tetrahydro-2H-pyran-4-carboxamide (Formula (II)), or 1-(2-(cyclopropanesulfonamido)pyrimidin-4-yl)-N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)cyclohexane-1-carboxamide (Formula (III)).

Abstract: A furniture leg protector apparatus for preventing stubbed toes includes an anchor base having a base top side, a base bottom side, and a base perimeter. The base top side is placed underneath a leg of a furniture item. A wraparound backing has a backing top edge, a backing bottom edge, a backing left edge, a backing right edge, a backing inner face, and a backing outer face. A midpoint of the backing bottom edge is coupled to the base top side proximal the base perimeter. The wraparound backing moves between a planar position and a wrapped position to encompass the leg of the furniture item with the backing inner face. An outer layer is coupled to the wraparound backing. The outer layer is continuously coupled to the backing outer face and is sufficiently shock-absorptive to prevent injury to a person's toes when accidentally kicked.

Abstract: Compounds of formula (I), and related aspects.

Abstract: Compounds of formula (I) and related aspects.

Abstract: Systems and methods for managing loads on a power grid are provided. The load control system includes one or more energy sources connected to a common bus and a first device connected in series between the common bus and a first load. The first device may be an automatic transfer switch. The first device may include switching hardware configured to connect and disconnect the first load from the common bus and a load control circuit configured to cause the first load to disconnect from the common bus after a pre-determined amount of time detecting a trigger.

Abstract: A method of power transfer control among a plurality of power sources coupled through a distribution system. The method comprises determining, at each power source of the plurality of power sources, an assignment of priorities for each of the plurality of power sources. The method also comprises obtaining, at each power source, information indicating an availability of each of the plurality of power sources and determining a set of available power sources, and identifying, at each power source, a preferred power source and a standby power source from the plurality of power sources. The method further comprises determining to change the preferred power source from a first power source to a second power source in response to detecting a condition, and conducting the power transfer.

Abstract: A method of power transfer control among a plurality of power sources coupled through a distribution system. The method comprises determining, at each power source of the plurality of power sources, an assignment of priorities for each of the plurality of power sources. The method also comprises obtaining, at each power source, information indicating an availability of each of the plurality of power sources and determining a set of available power sources, and identifying, at each power source, a preferred power source and a standby power source from the plurality of power sources. The method further comprises determining to change the preferred power source from a first power source to a second power source in response to detecting a condition, and conducting the power transfer.

Abstract: Compounds of formula (I): and related aspects.

Abstract: Compounds of formula (I): (I) and related aspects.