Patents by Inventor Andrew O. Brightman

Andrew O. Brightman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gastric submucosal tissue as a novel diagnostic tool
    Patent number: 8647677
    Abstract: A cell culture growth substrate comprising submucosal tissue of a warm-blooded vertebrate and a method for culturing fastidious organisms is described. Submucosal tissue used in accordance with the present invention supports the proliferation of cells when said cells are contacted with submucosal tissue under conditions conducive to cell proliferation.
    Type: Grant
    Filed: July 15, 2009
    Date of Patent: February 11, 2014
    Assignee: Purdue Research Foundation
    Inventors: Stephen F. Badylak, Sherry L. Voytik-Harbin, Matthew S. Waninger, Andrew O. Brightman
  • Gastric Submucosal Tissue as a Novel Diagnostic Tool
    Publication number: 20100041135
    Abstract: A cell culture growth substrate comprising submucosal tissue of a warm-blooded vertebrate and a method for culturing fastidious organisms is described. Submucosal tissue used in accordance with the present invention supports the proliferation of cells when said cells are contacted with submucosal tissue under conditions conducive to cell proliferation.
    Type: Application
    Filed: July 15, 2009
    Publication date: February 18, 2010
    Inventors: Stephen F. Badylak, George B. Boder, Sherry L. Voytik-Harbin, Matthew S. Waninger, Andrew O. Brightman
  • Submucosa gel compositions
    Patent number: 7147871
    Abstract: A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable for inducing cell proliferation and growth both in vivo and in vitro.
    Type: Grant
    Filed: September 3, 2002
    Date of Patent: December 12, 2006
    Assignee: Purdue Research Foundation
    Inventors: Sherry L. Voytik-Harbin, Andrew O. Brightman, Ryan M. Meixner, Beverly Z. Waisner
  • Submucosa gel compositions
    Publication number: 20030012823
    Abstract: A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable for inducing cell proliferation and growth both in vivo and in vitro.
    Type: Application
    Filed: September 3, 2002
    Publication date: January 16, 2003
    Inventors: Sherry L. Voytik-Harbin, Andrew O. Brightman, Ryan M. Meixner, Beverly Z. Waisner
  • Submucosa gel compositions
    Publication number: 20030012822
    Abstract: A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable for inducing cell proliferation and growth both in vivo and in vitro.
    Type: Application
    Filed: September 3, 2002
    Publication date: January 16, 2003
    Inventors: Sherry L. Voytik-Harbin, Andrew O. Brightman, Ryan M. Meixner, Beverly Z. Waisner
  • Submucosa gel compositions
    Patent number: 6444229
    Abstract: A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable for inducing cell proliferation and growth both in vivo and in vitro.
    Type: Grant
    Filed: July 23, 2001
    Date of Patent: September 3, 2002
    Assignee: Purdue Research Foundation
    Inventors: Sherry L. Voytik-Harbin, Andrew O. Brightman, Ryan M. Meixner, Beverly Z. Waisner
  • Submucosa extracts
    Patent number: 6375989
    Abstract: A method for preparing a bioactive extract from warm-blooded vertebrate submucosal tissue is described. The submucosal tissue is extracted using an aqueous solution of extraction excipients, and the extracted bioactive components are then separated from the extraction excipients to provide an isolated extract enriched in bioactive components. The isolated extract is useful, inter alia, as additive for cell growth media to promote cell growth and proliferation in vitro.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: April 23, 2002
    Assignee: Purdue Research Foundation
    Inventors: Stephen F. Badylak, Andrew O. Brightman, Jason P. Hodde, Timothy B. McPherson, Sherry L. Voytik-Harbin
  • Submucosa gel compositions
    Publication number: 20020001626
    Abstract: A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable for inducing cell proliferation and growth both in vivo and in vitro.
    Type: Application
    Filed: July 23, 2001
    Publication date: January 3, 2002
    Inventors: Sherry L. Voytik-Harbin, Andrew O. Brightman, Ryan M. Meixner, Beverly Z. Waisner
  • Submucosa as a growth substrate for cells
    Patent number: 6264992
    Abstract: A composition comprising enzymatically digested submucosa of a warm-blooded vertebrate and a method of making that composition is described. More particularly the submucosa is enzymatically digested and gelled to form a shape retaining gel matrix suitable for inducing cell proliferation and growth both in vivo and in vitro.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: July 24, 2001
    Assignee: Purdue Research Foundation
    Inventors: Sherry L. Voytik-Harbin, Andrew O. Brightman, Ryan M. Meixner, Beverly Z. Waisner
  • Stomach submucosa derived tissue graft
    Patent number: 6099567
    Abstract: A tissue graft composition comprising stomach submucosal tissue delaminated from both the luminal portion of the tunica mucosa and the smooth muscle layers of the muscularis externa of a stomach of a warm blooded vertebrate is described. The graft composition can be or implanted into a host to replace or support damaged or diseased tissues.
    Type: Grant
    Filed: May 4, 1999
    Date of Patent: August 8, 2000
    Assignee: Purdue Research Foundation
    Inventors: Stephen F. Badylak, Sherry L. Voytik-Harbin, Andrew O. Brightman, Robert S. Tullius