Abstract: The invention is a novel series of cyclic amino acids which are useful in the treatment of epilepsy, faintness attacks, neurodegenerative disorders, depression, anxiety, panic, pain, neuropathological disorders, gastrointestinal disorders such as irritable bowel syndrome (IBS), and inflammation, especially arthritis. A pharmaceutical composition containing a compound of the invention as well as methods of preparing the compounds and novel intermediates useful in the preparation of the final compounds are included.

Abstract: A can end is manufactured by forming an end shell comprising a radially outer seaming flange, a chuck wall adjacent the seaming flange, a center panel, and an axially downward countersink joining the center panel to the chuck wall below the level of the seaming flange. The end shell is converted to an easy-open can end by forming a score on a portion of the center panel, raising a rivet on the center pane, and forming a tab and attaching the tab to the rivet. The end is subsequently formed by moving the center panel and the seaming flange one with respect to the other to raise the center panel above the level of the seaming flange.

Abstract: A can end is manufactured by forming an end shell comprising a radially outer seaming flange, a chuck wall adjacent the seaming flange, a center panel, and an axially downward countersink joining the center panel to the chuck wall below the level of the seaming flange. The end shell is converted to an easy-open can end by forming a score on a portion of the center panel, raising a rivet on the center pane, and forming a tab and attaching the tab to the rivet. The end is subsequently formed by moving the center panel and the seaming flange one with respect to the other to raise the center panel above the level of the seaming flange.

Abstract: The present invention relates to a repository which stores properties of database objects. The repository includes a first store for storing a number of predetermined properties, and a second store for storing additional properties. A processor is provided for determining or modifying the properties stored in the first and second stores.

Abstract: The present invention relates to a query generator for generating a query for obtaining selected data from a database. The query generator includes a processor which is adapted to receive an input indicating the selected data to be obtained. The processor then analyses the input to determine whether the input requires a joining of data in different tables, and an aggregation step. If so, the processor generates a query which causes the database to aggregate the data within each of the tables as required; and, join the aggregated data, the joined aggregated data representing the selected data.