Patents by Inventor Andrew P. Capaldi

Andrew P. Capaldi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS FOR IMMUNOLABELING
    Publication number: 20240361306
    Abstract: Isolated antibody compositions for immunolabeling are described herein. These compositions overcome many of the limitations currently involved with immunolabeling such as low fluorescence and high noise signal.
    Type: Application
    Filed: April 26, 2024
    Publication date: October 31, 2024
    Inventors: Arron Sullivan, Andrew P. Capaldi, Roderick Capaldi, Nikita Fernandes
  • Methods and compositions for treating eukaryotic infections via altering aggregation dynamics of Raptor/KOG1
    Patent number: 11478497
    Abstract: Methods and compositions for activating TORC1 aggregate formation in a fungi or a parasite, wherein TORC1 aggregate formation inhibits growth of the fungi or parasite. TORC1 aggregate formation may be activated using small molecules or other agents, and said agents may be used to treat or prevent a disease or condition associated with the fungi and parasite. The agent may target Kog1 of TORC1, e.g., the agent may directly or indirectly inhibit Kog1 leading to aggregation of the TORC1 complex.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: October 25, 2022
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Andrew P. Capaldi, James E. Hughes Hallett
  • METHODS AND COMPOSITIONS FOR TREATING EUKARYOTIC INFECTIONS VIA ALTERING AGGREGATION DYNAMICS OF RAPTOR/KOG1
    Publication number: 20220168328
    Abstract: Methods and compositions for activating TORC1 aggregate formation in a fungi or a parasite, wherein TORC1 aggregate formation inhibits growth of the fungi or parasite. TORC1 aggregate formation may be activated using small molecules or other agents, and said agents may be used to treat or prevent a disease or condition associated with the fungi and parasite. The agent may target Kog1 of TORC1, e.g., the agent may directly or indirectly inhibit Kog1 leading to aggregation of the TORC1 complex.
    Type: Application
    Filed: February 14, 2022
    Publication date: June 2, 2022
    Inventors: Andrew P. Capaldi, James E. Hughes Hallett
  • Methods and compositions for treating eukaryotic infections via altering aggregation dynamics of Raptor/KOG1
    Patent number: 11246880
    Abstract: Methods and compositions for activating TORC1 aggregate formation in a fungi or a parasite, wherein TORC1 aggregate formation inhibits growth of the fungi or parasite. TORC1 aggregate formation may be activated using small molecules or other agents, and said agents may be used to treat or prevent a disease or condition associated with the fungi and parasite. The agent may target Kog1 of TORC1, e.g., the agent may directly or indirectly inhibit Kog1 leading to aggregation of the TORC1 complex.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: February 15, 2022
    Assignee: ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
    Inventors: Andrew P. Capaldi, James E. Hughes Hallett
  • METHODS AND COMPOSITIONS FOR TREATING EUKARYOTIC INFECTIONS VIA ALTERING AGGREGATION DYNAMICS OF RAPTOR/KOG1
    Publication number: 20170360820
    Abstract: Methods and compositions for activating TORC1 aggregate formation in a fungi or a parasite, wherein TORC1 aggregate formation inhibits growth of the fungi or parasite. TORC1 aggregate formation may be activated using small molecules or other agents, and said agents may be used to treat or prevent a disease or condition associated with the fungi and parasite. The agent may target Kog1 of TORC1, e.g., the agent may directly or indirectly inhibit Kog1 leading to aggregation of the TORC1 complex.
    Type: Application
    Filed: December 18, 2015
    Publication date: December 21, 2017
    Applicant: The Arizona Board of Regents on Behalf of the University of Arizona
    Inventors: Andrew P. Capaldi, James E. Hughes Hallett