Patents by Inventor Andrew P. Fosberry

Andrew P. Fosberry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • pth
    Publication number: 20020106776
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: June 8, 2001
    Publication date: August 8, 2002
    Inventors: Sanjoy Biswas, Martin K. Burnham, Andrew P. Fosberry, John E. Hodgson, Elizabeth J. Lawlor, Tong Li, Damien McDevitt, Christopher Michael Traini, Martin Rosenberg, Judith Ward, Richard Lloyd Warren, Magdalena Zalacain
  • SigB
    Patent number: 6310192
    Abstract: SigB polypeptides and DNA (RNA) encoding such SigB and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such SigB for the treatment of infection, particularly bacterial infections. Antagonists against such SigB and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of SigB nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: October 30, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham PLC
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas
  • RsbV-1 from staphylococcus aureus
    Patent number: 6297358
    Abstract: RsbV-1 polypeptides and DNA (RNA) encoding such RsbV-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such RsbV-1 for the treatment of infection, particularly bacterial infections. Antagonists against such RsbV-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of RsbV-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: August 23, 1999
    Date of Patent: October 2, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas
  • pth
    Patent number: 6274361
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: August 14, 2001
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Sanjoy Biswas, Martin K. R. Burnham, Andrew P. Fosberry, John E Hodgson, Elizabeth J Lawlor, Tong Li, Damien McDevitt, Christopher Michael Traini, Martin Rosenberg, Judith Ward, Richard Lloyd Warren, Magdalena Zalacain
  • Staphylococcus aureus rsbU-1
    Patent number: 6111078
    Abstract: rsbU-1 polypeptides and DNA (RNA) encoding such rsbU-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such rsbU-1 for the treatment of infection, particularly bacterial infections. Antagonists against such rsbU-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of rsbU-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: June 28, 1999
    Date of Patent: August 29, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas
  • RsbW-1 protein
    Patent number: 6066717
    Abstract: RsbW-1 polypeptides and DNA (RNA) encoding such RsbW-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such RsbW-1 for the treatment of infection, particularly bacterial infections. Antagonists against such RsbW-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of RsbW-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: May 23, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas
  • RsbV-1 polynucleotides of Staphylococcus aureus
    Patent number: 6020160
    Abstract: RsbV-1 polypeptides and DNA (RNA) encoding such RsbV-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such RsbV-1 for the treatment of infection, particularly bacterial infections. Antagonists against such RsbV-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of RsbV-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: February 1, 2000
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas
  • Staphylococcus aureus RSBU-1
    Patent number: 6004556
    Abstract: rsbU-1 polypeptides and DNA (RNA) encoding such rsbU-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such rsbU-1 for the treatment of infection, particularly bacterial infections. Antagonists against such rsbU-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of rsbU-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: December 21, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas
  • RsbW-1 encoding nucleic acids
    Patent number: 5942419
    Abstract: RsbW-1 polypeptides and DNA (RNA) encoding such RsbW-1 and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such RsbW-1 for the treatment of infection, particularly bacterial infections. Antagonists against such RsbW-1 and their use as a therapeutic to treat infections, particularly bacterial infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of RsbW-1 nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding SigB operon and for detecting the polypeptide in a host.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: August 24, 1999
    Assignee: SmithKline Beecham p.l.c.
    Inventors: Andrew P Fosberry, Elizabeth J Lawlor, Richard O Nicholas