Abstract: An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment. The instrument may be particularly useful in procedures performed in a gastrointestinal tract, where bowel perforation is a concern, or in the pancreas, where damage to the portal vein or the pancreatic duct may occur when a tumor or other abnormality is being resected, dissected or removed.

Abstract: An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment. The instrument may be particularly useful in procedures performed in a gastrointestinal tract, where bowel perforation concern, or in the pancreas, where damage to the portal vein or the pancreatic duct may occur when a tumor or other abnormality is being resected, dissected or removed.

Abstract: An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment. The instrument may be particularly useful in procedures performed in a gastrointestinal tract, where bowel perforation is a concern, or in the pancreas, where damage to the portal vein or the pancreatic duct may occur when a tumor or other abnormality is being resected, dissected or removed.

Abstract: An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment. The instrument may be particularly useful in procedures performed in a gastrointestinal tract, where bowel perforation is a concern, or in the pancreas, where damage to the portal vein or the pancreatic duct may occur when a tumour or other abnormality is being resected, dissected or removed.

Abstract: A flexible RF device (1) can be deployed through a flexible endoscope. An electrode structure has a central electrode (12) and outer electrode (11). Flexible electrodes (30), circular electrodes (51, 53) and circular loop assemblies (55, 56) with different diameters are also disclosed, as well a tweezer electrodes (41) with pads (43) for increasing contact area. Retractable electrodes (100) are also disclosed.

Abstract: A device for the treatment of tumours comprising an elongate catheter (102), a plurality of flexible needles (402) confined within the catheter which, when extended therefrom, take up a curved form and which, together, define a structure for surrounding a tumour to be treated; the needles being arranged to heat and embolise a shell of tissue surrounding the tumour, thereby cutting off the tumour's blood supply. The invention further extends to a method of treatment using such a device.

Abstract: A device includes an applicator and electrode needles forming two rows. Needles may be inserted into tissue and electromagnetic power may be applied thereto, following which a blade may be used to cut the tissue. The blade may be located between or outside and parallel to needle rows. The blade is located on an actuator operable by a handle, which may be in the form of a rod.

Abstract: A catheter (4) may be introduced into the body of a patient to provide electromagnetic power, such as RF power, directly to a stent (2) to cause heating of surrounding tissue for ablation. The stent may have a conducting portion (14) and insulated portions (13). Struts (15) on the catheter may be deployed by a balloon (103) to contact the stent. The stent may have radial or sector segments (16) which may be individually powered for treating asymmetric tumours.

Abstract: The present invention provides a method for introducing nucleic acid (30) into cells of a region of the human or animal body, which method comprises substantially occluding an efferent vessel from said body region and introducing said nucleic into that body region under pressure via said efferent vessel and further apparatus for introducing nucleic acid into cells of a region of the body comprising: a reservoir for holding a liquid formulation which comprises said nucleic acid; a catheter tube in fluid communication with said reservoir for conveying said liquid formulation to said body region via an efferent vessel of said body region; pressure development means for pressurising the liquid conveyed by the catheter; and occlusion means (8) for substantially occluding said efferent vessel.

Abstract: The present invention provides a method in which a formulation comprising cells and a magnetic material is administered to a subject and part of the body of said subject is subjected to a magnetic field, as well as a kit for use in this method. A medical device for use in this method is also provided.