Abstract: In implementations of adaptive systems for continuous glucose monitoring (CGM), a computing device implements an adaptive system to receive glucose data describing user glucose values measured by a sensor of a CGM system, the sensor is inserted at an insertion site. The adaptive system accesses orientation data describing forces measured by an accelerometer of the CGM system, and the adaptive system identifies a location of the insertion site based on the orientation data. Modified glucose data is generated by modifying the user glucose values based on the location of the insertion site. The adaptive system generates an indication of the modified glucose data for display in a user interface of a display device.

Abstract: A method of evaluating or monitoring the medical state of a human subject on the subject includes the steps of: positioning an antenna side of a self-contained radio apparatus for non-invasive, thoracic radio interrogation of a human subject proximally to the heart of the human subject; providing a radio frequency interrogation interference signal from the human subject, the radio frequency interrogation interference signal being low frequency components of reflections of a radio interrogation signal transmitted into the thorax of the subject; and determining with the apparatus on the subject at least at least one stroke volume value of the subject from radio frequency interrogation interference signal generated by the apparatus.

Abstract: A relative positioning system and method has an adjoining pair of spaced apart receivers positioned proximal to an object causing a signal interference with a radio frequency signal detectable by each receiver of the adjoining pair. The radio frequency signal is associated with an emitter. Control electronics operatively couple the spaced apart receivers. The control electronics are configured to determine a direction of the emitter based on the signal interference. In an embodiment of the system and method the emitter is associated with an object of interest, the signal encodes information relating to the identity and status of the object, and information and heading of the object are cutaneously communicated to an operator by an article worn by the operator.

Abstract: A relative positioning system and method has an adjoining pair of spaced apart receivers positioned proximal to an object causing a signal interference with a radio frequency signal detectable by each receiver of the adjoining pair. The radio frequency signal is associated with an emitter. Control electronics operatively couple the spaced apart receivers. The control electronics are configured to determine a direction of the emitter based on the signal interference. In an embodiment of the system and method the emitter is associated with an object of interest, the signal encodes information relating to the identity and status of the object, and information and heading of the object are cutaneously communicated to an operator by an article worn by the operator.

Abstract: A radio apparatus and method for non-invasive, thoracic radio interrogation of a subject for the collection of hemodynamic, respiratory and/or other cardiopulmonary related data from the subject includes a antenna positionable proximally to the subject, a radio transmitter transmitting an unmodulated radio interrogation signal of a predetermined fixed frequency at a safe level of about 1 milliwatt or less from the antenna into the subject and a radio receiver capturing through the antenna, reflections of the transmitted radio interrogation signal returned from the subject. A Doppler component of the reflections contains the data that can be extracted from the captured reflections.

Abstract: A method of evaluating or monitoring the medical state of a subject comprising the steps of: providing a radio frequency interrogation interference signal from a subject, the radio frequency interrogation interference signal being low frequency components of reflections of a radio interrogation signal transmitted into the thorax of the subject; and determining at least one cardiac or respiratory characteristic of the subject from radio frequency interrogation interference signal. The characteristic can be compared to predetermined values to assess current state or monitored for changes over time to assess change in condition of the subject.

Abstract: A relative positioning system and method has an adjoining pair of spaced apart receivers positioned proximal to an object causing a signal interference with a radio frequency signal detectable by each receiver of the adjoining pair. The radio frequency signal is associated with an emitter. Control electronics operatively couple the spaced apart receivers. The control electronics are configured to determine a direction of the emitter based on the signal interference. In an embodiment of the system and method the emitter is associated with an object of interest, the signal encodes information relating to the identity and status of the object, and information and heading of the object are cutaneously communicated to an operator by an article worn by the operator.

Abstract: A relative positioning system and method has an adjoining pair of spaced apart receivers positioned proximal to an object causing a signal interference with a radio frequency signal detectable by each receiver of the adjoining pair. The radio frequency signal is associated with an emitter. Control electronics operatively couple the spaced apart receivers. The control electronics are configured to determine a direction of the emitter based on the signal interference. In an embodiment of the system and method the emitter is associated with an object of interest, the signal encodes information relating to the identity and status of the object, and information and heading of the object are cutaneously communicated to an operator by an article worn by the operator.

Abstract: A liquid sample dispenser for use with an optical analysis disc. The dispenser includes a body portion, a tip portion connected to the body portion, first and second retainer members moveably supported within the tip portion, and a sealant contained between the first and second retainer members. One of the retainer members also functions as an inlet stopper. The associated optical analysis disc includes a substrate and a channel layer associated with the substrate. The disc further includes a cover portion located so that the channel layer is positioned between the substrate and the cover portion. An inlet port formed in the cover portion is adapted to receive a test sample from the tip portion of the dispenser. The sample is loaded form the dispenser into the disc followed by the inlet stopper and sealant to seal the sample in the disc. Related methods for loading a biological sample into the analysis disc through the dispenser, and sealing the disc inlet are also provided.

Abstract: Devices, systems, and methods for detecting and preventing unauthorized access to computer networks. Devices include a server enabled with an application that interacts with a counter-part PC application to determine whether input devices of the PC have been active within a predetermined time. Methods include providing a subscription-based service for PC users to determine whether unauthorized network output activity has occurred from a respective user's PC.

Abstract: Personal diagnostic devices including diagnostic patches (bio-patches) and interactive medical bracelets (bio-bracelets) are provided with a skin/patch interface, at least one analysis layer, a signal processing layer, and a user output interface. Embodiments of the interactive diagnostic devices may include micro-fluidic circuits with reaction chambers, analysis chambers, mixing cambers, and various pre-disposed chemistries or reagents for performing a wide verity of tests by trans-dermal transport of blood or perspiration. Sample collection chambers for the fluidic circuit may include minimally invasive tubules that penetrate the skin surface to acquire blood samples from capillaries near the epidermis. Alternate implementations of the personal diagnostic device may be equipped with logic processing, input/output devices, acoustic microphones, cryogenic circuits, embedded processors, electrical control circuitry, and battery current sources or photovoltaic sources of electrical power.

Abstract: Methods and apparatus for extracting data from an optical analysis disc such as a bio-disc are disclosed. The process of capturing the data is controlled by a single computer. In one embodiment, a template is provided in determining the location of desired sample regions. In another embodiment, one or more ditches are obliterated on the disc in determining the location of the desired samples. In one embodiment, a user enters measured distances to a control program to indicate the sample region location. The user may specify the sample rate. The user may also specify the number of capture regions. In one embodiment, capture regions are separated by radial lines. The head of a disc drive may be maintained at a constant radial distance. This distance is maintained to cause the disc to act as a centrifuge at a desired speed.