Abstract: A dry powder inhaler comprises at least one medicament reservoir and a closure member engaged with the reservoir so as to close an opening therein. A surface of the reservoir adjacent the opening and a surface of the closure member are in abutment, either directly or via a seal member interposed between the reservoir and the closure member. At least one abutting surface is formed with a projection that increases the contact pressure between said surfaces, thereby improving the seal between them and reducing the potential for ingress of moisture between said surfaces into the reservoir.

Abstract: A dry powder inhaler comprises at least one medicament reservoir and a closure member engaged with the reservoir so as to close an opening therein. A surface of the reservoir adjacent the opening and a surface of the closure member are in abutment, either directly or via a seal member interposed between the reservoir and the closure member. At least one abutting surface is formed with a projection that increases the contact pressure between said surfaces, thereby improving the seal between them and reducing the potential for ingress of moisture between said surfaces into the reservoir.

Abstract: A cast mould for use in the manufacture of a contact lens by the polymerisation of a flowable precursor comprises a female mould part and a male mould part. The female mould part has a concave first surface region adapted to receive the flowable precursor in use, and a second surface region. The male mould part has a convex first surface region and a second surface region. The male mould part is engageable with the female mould part to define a lens-forming recess between the concave and convex surface regions and to define a first overflow cavity between said second surface regions. The first overflow cavity is adapted to receive excess flowable precursor displaced from the lens-forming recess in use, and the first overflow cavity is provided with first retaining means such that, in use, after polymerisation, polymer in the first overflow cavity is mechanically interlocked with a single one of the mould parts after separation of the mould parts.