Patents by Inventor Andrew Peter HATAS

Andrew Peter HATAS has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bispecific antibodies having constant region mutations and uses therefor
    Patent number: 11459405
    Abstract: Described herein are mutations in the CH1/CL interface and CH3 constant regions of a bispecific antibody which facilitate heterodimerization and methods for the efficient production of bispecific antibodies. Also disclosed are therapeutic and diagnostic methods for using the antibodies.
    Type: Grant
    Filed: December 28, 2016
    Date of Patent: October 4, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Ram Sasisekharan, Kannan Tharakaraman, Vidya Subramanian, Eduardo Fleischer, Andrew Peter Hatas
  • BISPECIFIC ANTIBODIES HAVING CONSTANT REGION MUTATIONS AND USES THEREFOR
    Publication number: 20190023810
    Abstract: Described herein are mutations in the CHl/CL interface and CH3 constant regions of a bispecific antibody which facilitate heterodimerization and methods for the efficient production of bispecific antibodies. Also disclosed are therapeutic and diagnostic methods for using the antibodies.
    Type: Application
    Filed: December 28, 2016
    Publication date: January 24, 2019
    Applicants: Massachusetts Institute of Technology, Massachusetts Institute of Technology
    Inventors: Ram SASISEKHARAN, Kannan THARAKARAMAN, Vidya SUBRAMANIAN, Eduardo FLEISCHER, Andrew Peter HATAS