Abstract: A catheter assembly is provided having a working lumen and a guide. The guide is configured to position a fragmentizing device within the working lumen. The guide is configured to prevent or minimize any unintended movement of a distal section of the fragmentizing device within the working lumen when the distal section of the fragmentizing device is positioned at a distal end of the working lumen.

Abstract: A vaporizer device includes various modular components. The vaporizer device includes a first subassembly. The first subassembly includes a cartridge connector that secures a vaporizer cartridge to the vaporizer device and includes at least two receptacle contacts that electrically communicate with the vaporizer cartridge. The vaporizer device includes a second subassembly. The second subassembly includes a skeleton defining a rigid tray that retains at least a power source. The vaporizer device also includes a third subassembly. The third subassembly includes a plurality of charging contacts that supply power to the power source, and an end cap that encloses an end of the vaporizer device.

Abstract: Systems and methods of rendering effects are described herein. A computing device can receive a user selection of an effect to be applied during gameplay of a computer game. The computing device can initiate a framework with which to apply the effect during the gameplay. The computing device can determine scenes during the gameplay to apply the effect through the framework. The computing device can determine graphical elements in the scenes that correspond to non-user interface elements through the framework. The computing system can apply the effect to the graphical elements through the framework.

Abstract: A system includes a current source circuit; a system power input; and load switching circuitry coupling the current source circuit and the system power input to an output configured to couple to a vaporizer heating element. The current source circuit, the system power input, and the load switching circuitry form part of an integrated circuit. Related apparatus, systems, techniques, and articles are also described.

Abstract: A system for developing software provides automatically identifies, based on wireframe images, features from a library of features for a custom software application, implements simulations of a plurality of the features available for demonstration through the graphical user interface, stores blocks of source code for each feature in a source code repository wherein the blocks are adapted to provide an actual application when compiled by developers, receives from the client device, by a server running a software building component, one or more selected features for the software application, automatically integrates, by the software building component, the one or more selected features to generate an integrated feature set based on attributes of each of the selected features and an inter-feature rules set, and generates an interactive visualization of a navigable prototype of the software application based on the integrated feature set.

Abstract: Described are systems and methods for managing data traffic to a plurality of mobile devices over a wireless network. For each mobile device, a facility is provided that is capable of: (i) assigning a utility function to mathematically represent the value of a plurality of applications running on that mobile device with respect to a factor, (ii) aggregating the plurality of utility functions to generate an aggregated utility function corresponding to that mobile device, and (ii) communicating at least one of the associated aggregate utility function and a bid price based on the associated aggregate utility function over a network. A resource allocation is determined among a plurality of mobile devices based on a bidding process which accounts for the aggregate utility functions, and the data traffic between the mobile devices and the resource is managed using a network traffic shaping element according to the resource allocation.

Abstract: Described are systems and methods for managing data traffic to a plurality of mobile devices over a wireless network. For each mobile device, a facility is provided that is capable of: (i) assigning a utility function to mathematically represent the value of a plurality of applications running on that mobile device with respect to a factor, (ii) aggregating the plurality of utility functions to generate an aggregated utility function corresponding to that mobile device, and (ii) communicating at least one of the associated aggregate utility function and a bid price based on the associated aggregate utility function over a network. A resource allocation is determined among a plurality of mobile devices based on a bidding process which accounts for the aggregate utility functions, and the data traffic between the mobile devices and the resource is managed using a network traffic shaping element according to the resource allocation.

Abstract: The present invention relates to multi-well platforms, lids, caddies and any combination thereof. The multi-well platforms comprise a plurality of wells that can be of any shape and can be arranged in any ornamental pattern. The lid comprises an area corresponding to the well field. The caddy has a footprint approximately that of a standard 96-well microtiter plate. When the multi-well platform is engaged with the caddy, the wells of the well-field of the multi-well platform are preferably not obscured by the caddy when viewed from the bottom of the combination.

Abstract: The present invention relates to multi-well platforms, lids, caddies and any combination thereof. The multi-well platforms comprise a plurality of wells that can be of any shape and can be arranged in any ornamental pattern. The lid comprises an area corresponding to the well field. The caddy has a footprint approximately that of a standard 96-well microtiter plate. When the multi-well platform is engaged with the caddy, the wells of the well-field of the multi-well platform are preferably not obscured by the caddy when viewed from the bottom of the combination.

Abstract: The present invention relates to multi-well platforms, lids, caddies and any combination thereof. The multi-well platforms comprise a plurality of wells that can be of any shape and can be arranged in any ornamental pattern. The lid comprises an area corresponding to the well field. The caddy has a footprint approximately that of a standard 96-well microtiter plate. When the multi-well platform is engaged with the caddy, the wells of the well-field of the multi-well platform are preferably not obscured by the caddy when viewed from the bottom of the combination.

Abstract: The invention provides for a detector assembly, fiber assembly and screening system for optical measurements.

Abstract: One aspect of the present invention is a multi-well platform for fluorescence measurements, comprising a plurality of wells within a frame, wherein the multi-well platform has low fluorescence background. Another aspect of the present invention is a system for spectroscopic measurements, comprising reagents for an assay and a multi-well platform for fluorescence measurements. A further aspect of the present invention is a method for detecting the presence of an analyte in a sample contained in a multi-well platform by detecting light emitted from the sample. Another aspect of the present invention is a method from identifying a modulator of a biological process or target in a sample contained in a multi-well platform by detecting light emitted from the sample. Another aspect of the present invention is a composition identified by this method. A further aspect of the present invention is a method to identify a therapeutic.

Abstract: The invention provides for a detector assembly, fiber assembly and screening system for optical measurements.

Abstract: The invention provides for a detector assembly, fiber assembly and screening system for optical measurements.

Abstract: The invention provides for a detector assembly, fiber assembly and screening system for optical measurements.

Abstract: The present invention relates to multi-well platforms, lids, caddies and any combination thereof. The multi-well platforms comprise a plurality of wells that can be of any shape and can be arranged in any ornamental pattern. The lid comprises an area corresponding to the well field. The caddy has a footprint approximately that of a standard 96-well microtiter plate. When the multi-well platform is engaged with the caddy, the wells of the well-field of the multi-well platform are preferably not obscured by the caddy when viewed from the bottom of the combination.

Abstract: The present invention relates to multi-well platforms, lids, caddies and any combination thereof. The multi-well platforms comprise a plurality of wells that can be of any shape and can be arranged in any ornamental pattern. The lid comprises an area corresponding to the well field. The caddy has a footprint approximately that of a standard 96-well microtiter plate. When the multi-well platform is engaged with the caddy, the wells of the well-field of the multi-well platform are preferably not obscured by the caddy when viewed from the bottom of the combination.

Abstract: One aspect of the present invention is a multi-well platform for fluorescence measurements, comprising a plurality of wells within a frame, wherein the multi-well platform has low fluorescence background. Another aspect of the present invention is a system for spectroscopic measurements, comprising reagents for an assay and a multi-well platform for fluorescence measurements. A further aspect of the present invention is a method for detecting the presence of an analyte in a sample contained in a multi-well platform by detecting light emitted from the sample. Another aspect of the present invention is a method from identifying a modulator of a biological process or target in a sample contained in a multi-well platform by detecting light emitted from the sample. Another aspect of the present invention is a composition identified by this method. A further aspect of the present invention is a method to identify a therapeutic.

Abstract: One aspect of the present invention is a multi-well platform for fluorescence measurements, comprising a plurality of wells within a frame, wherein the multi-well platform has low fluorescence background. Another aspect of the present invention is a system for spectroscopic measurements, comprising reagents for an assay and a multi-well platform for fluorescence measurements. A further aspect of the present invention is a method for detecting the presence of an analyte in a sample contained in a multi-well platform by detecting light emitted from the sample. Another aspect of the present invention is a method from identifying a modulator of a biological process or target in a sample contained in a multi-well platform by detecting light emitted from the sample. Another aspect of the present invention is a composition identified by this method. A further aspect of the present invention is a method to identify a therapeutic.

Abstract: The invention provides for a detector assembly, fiber assembly and screening system for optical measurements.