Patents by Inventor Andrew Polson

Andrew Polson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-B7-H4 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20160017040
    Abstract: The disclosure provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 21, 2016
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20150314016
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: June 9, 2015
    Publication date: November 5, 2015
    Applicant: GENENTECH, INC.
    Inventors: Yvonne CHEN, Mark DENNIS, David DORNAN, Kristi ELKINS, Jagath Reddy JUNUTULA, Andrew POLSON, Bing ZHENG
  • Anti-LGR5 antibodies and immunoconjugates
    Patent number: 9175089
    Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
    Type: Grant
    Filed: March 29, 2013
    Date of Patent: November 3, 2015
    Assignee: Genentech, Inc.
    Inventors: Jo-Anne Hongo, Weiguang Mao, Paul Polakis, Andrew Polson, Rajesh Vij, Yan Wu, Wei-Ching Liang
  • Anti-FcRH5 antibodies and immunoconjugates and methods of use
    Patent number: 9017951
    Abstract: A method of determining the presence of FcRH5 in a biological sample suspected of containing FcRH5 is provided comprising exposing the biological sample to an isolated monoclonal anti-FcRH5 antibody.
    Type: Grant
    Filed: November 9, 2012
    Date of Patent: April 28, 2015
    Assignee: Genenech, Inc.
    Inventors: Kristi Elkins, Andrew Polson, Allen Ebens, Camelia Adams, Bing Zheng, Jagath R. Junutula, Jo-Anne Hongo, Yan Wu
  • ANTHRACYCLINE DERIVATIVE CONJUGATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOR COMPOUNDS
    Publication number: 20150051380
    Abstract: The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.
    Type: Application
    Filed: October 30, 2014
    Publication date: February 19, 2015
    Applicant: Genentech, Inc.
    Inventors: Italo Beria, Michele Caruso, John A. Flygare, Vittoria Lupi, Rita Perego, Paul Polakis, Andrew Polson, Matteo Salsa, Susan D. Spencer, Barbara Valsasina, Robert L. Cohen
  • COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH A CD22 ANTIBODY-DRUG CONJUGATE
    Publication number: 20150010540
    Abstract: The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD22 antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD22 antibody-drug conjugate.
    Type: Application
    Filed: April 30, 2014
    Publication date: January 8, 2015
    Applicants: GENENTECH, INC., HOFFMANN-LA ROCHE INC.
    Inventors: Christian Klein, Sabine Lang, Pablo Umana, Andrew Polson
  • COMBINATION THERAPY OF AN AFUCOSYLATED CD20 ANTIBODY WITH A CD79b ANTIBODY-DRUG CONJUGATE
    Publication number: 20140356352
    Abstract: The present invention is directed to the combination therapy of an afucosylated anti-CD20 antibody with a CD79b antibody-drug conjugate for the treatment of cancer, especially to the combination therapy of CD20 expressing cancers with an afucosylated humanized B-Ly1 antibody and a CD79b antibody-drug conjugate.
    Type: Application
    Filed: April 30, 2014
    Publication date: December 4, 2014
    Applicants: GENENTECH, INC., HOFFMANN-LA ROCHE INC.
    Inventors: Christian Klein, Sabine Lang, Pablo Umana, Andrew Polson
  • Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds
    Patent number: 8900589
    Abstract: The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.
    Type: Grant
    Filed: July 14, 2009
    Date of Patent: December 2, 2014
    Assignee: Genetech, Inc.
    Inventors: Italo Beria, Michele Caruso, John A. Flygare, Vittoria Lupi, Rita Perego, Paul Polakis, Andrew Polson, Matteo Salsa, Susan D. Spencer, Barbara Valsasina, Robert L. Cohen
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20140335107
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: March 19, 2014
    Publication date: November 13, 2014
    Applicant: GENENTECH, INC.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson
  • ANTI-B7-H4 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20140322129
    Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: March 13, 2014
    Publication date: October 30, 2014
    Applicant: Genentech, Inc.
    Inventors: Steven R. Leong, Andrew Polson, Paul Polakis, Yan Wu, Wei-Ching Liang, Ron Firestein
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8722857
    Abstract: The present invention is directed to cysteine-engineered anti-CD79b antibody, huMA79b.v28, and compositions of matter thereof useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: May 13, 2014
    Assignee: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson
  • ANTI-FcRH5 ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20140106374
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: November 12, 2013
    Publication date: April 17, 2014
    Applicant: Genentech, Inc.
    Inventors: Kristi Elkins, Andrew Polson, Allen Ebens, Camelia Adams, Bing Zheng, Jagath R. Junutula, Jo-Anne Hongo, Yan Wu
  • Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20140099260
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: August 22, 2013
    Publication date: April 10, 2014
    Applicant: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8691531
    Abstract: The present invention is directed to compositions of matter comprising nucleic acids encoding a polypeptide comprising the amino acid sequence of SEQ ID NO: 207 or 208, encoding an anti-CD79b antibody comprising the heavy chain variable domain sequence of SEQ ID NO: 207 and the light chain variable domain sequence of SEQ ID NO: 208, or encoding an anti-CD79b antibody having : (i) a variable light chain comprising a HVR-L1 having the sequence of SEQ ID NO: 194, a HVR-L2 having the sequence of SEQ ID NO: 195, and a HVR-L3 having the sequence of SEQ ID NO: 196 and (ii) a variable light chain comprising a HVR-H1 having the sequence of SEQ ID NO: 202, a HVR-H2 having the sequence of SEQ ID NO: 203, and a HVR-H3 having the sequence of SEQ ID NO: 204, and vectors and host cells thereof.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: April 8, 2014
    Assignee: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20140030280
    Abstract: The invention provides anti-CD79b antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: July 8, 2013
    Publication date: January 30, 2014
    Applicant: Genentech, Inc.
    Inventors: Paul Polakis, Andrew Polson, Susan Diane Spencer, Shang-Fan Yu
  • ANTI-CD22 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20140030279
    Abstract: The invention provides anti-CD22 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: July 8, 2013
    Publication date: January 30, 2014
    Applicants: Spirogen Sarl, Genentech, Inc.
    Inventors: Paul Polakis, Andrew Polson, Susan Diane Spencer, Shang-Fan Yu, John A. Flygare, Janet L. Gunzner-Toste, Thomas Harden Pillow, Philip Wilson Howard, Luke Masterson
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20140030282
    Abstract: The invention provides anti-CD79b antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: July 8, 2013
    Publication date: January 30, 2014
    Applicant: Genentech, Inc.
    Inventors: Paul Polakis, Andrew Polson, Susan Diane Spencer, Shang-Fan Yu, Bing Zheng
  • ANTI-CD22 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20140030281
    Abstract: The invention provides anti-CD22 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: July 8, 2013
    Publication date: January 30, 2014
    Applicant: Genentech, Inc.
    Inventors: Paul Polakis, Andrew Polson, Susan Diane Spencer, Shang-Fan Yu, Bing Zheng
  • Anti-FcRH5 antibodies and immunoconjugates and methods of use
    Patent number: 8617559
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: December 31, 2013
    Assignee: Genetech, Inc.
    Inventors: Kristi Elkins, Andrew Polson, Allen Ebens, Camelia Adams, Bing Zheng, Jagath R. Junutula, Jo-Anne Hongo, Yan Wu
  • ANTI-LGR5 ANTIBODIES AND IMMUNOCONJUGATES
    Publication number: 20130336885
    Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
    Type: Application
    Filed: March 29, 2013
    Publication date: December 19, 2013
    Applicant: GENENTECH INC.
    Inventors: Jo-Anne Hongo, Weiguang Mao, Paul Polakis, Andrew Polson, Rajesh Vij, Yan Wu, Wei-Ching Liang