Abstract: Systems, methods, and apparatuses for storing and/or shipping an intraocular lens (IOL) cartridge are provided. A system comprises the IOL cartridge. The IOL cartridge comprises a nozzle and a compartment comprising an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge further comprises a dial disposed adjacent to the compartment, wherein an inner surface of the dial is exposed to the compartment. The dial is configured to fold the IOL upon rotation of the dial. The IOL cartridge further comprises a plunger case in fluid communication with the compartment, wherein a plunger is movably disposed within the plunger case. The IOL cartridge is configured to removably attach to a handpiece.

Abstract: The present invention relates to the formation of multi-domain specific binding molecules comprising VNARs. Specific binding domains that bind to Tumour Necrosis Factor alpha (TNF?) are also provided.

Abstract: Systems, methods, and apparatuses for storing and/or shipping an intraocular lens (IOL) cartridge are provided. A system comprises a packaging comprising a passage. The IOL cartridge is removably disposed within the passage. The IOL cartridge comprises a nozzle and a compartment configured to receive an IOL. The nozzle is in fluid communication with the compartment. The IOL cartridge further comprises a dial configured to rotate upon withdrawal of the IOL cartridge from the passage, wherein an inner surface of the dial is exposed to the compartment. The dial is configured to fold the IOL and release the IOL cartridge from the packaging upon rotation of the dial.

Abstract: According to an example aspect of the present disclosure, there is provided an apparatus comprising means for receiving, from a service network function, a request related to charging for a user equipment, means for determining whether to defer a consensus-based charging operation associated with the user equipment, means for transmitting to the service network function, when it is determined that the consensus-based charging operation is to be deferred, an indication indicating that the request is granted and means for refraining from transmitting any indication about the consensus-based charging associated with the user equipment until it is determined that the consensus-based charging operation associated with the user equipment is not to be deferred.

Abstract: The disclosure is directed to an Echo-Planar-Imaging (EPI) magnetic resonance imaging techniques combined with a variable-density undersampling scheme. The technique comprises generating an RF pulse, applying a switched frequency-encoding read out gradient in a variable time interval, and applying simultaneously an intermittently blipped low-magnitude phase-encoding gradient with a variable value of an integral of the phase-encoding gradient. The aforementioned steps are carried out such that the k-space is at least partially undersampled and the time interval of one read out gradient is varied depending on the integral of the phase encoding gradient, such that a ratio between the variable time interval of the read out gradient and the integral of the corresponding phase encoding gradient is kept above or at a predetermined constant value, which is related to a predetermined criteria of image quality.

Abstract: The present invention relates to receptor tyrosine kinase-like orphan receptor 1 (ROR1) specific antigen binding molecules and associated fusion proteins and conjugates. In a further aspect, the present invention relates to conjugated immunoglobulin-like shark variable novel antigen receptors (VNARs).

Abstract: Methods, systems, and devices related to a printer system that includes a first primary ink tank holding a dark-colored ink, a second primary ink tank holding a light-colored ink, a first selector valve configured to change a state, a first secondary ink tank connected to the first primary ink tank via the first selector valve, a second secondary ink tank connected to the first and second primary ink tanks via the first selector valve, a second selector valve connected to the first primary ink tank configured to return the dark-colored ink from the print heads to the first primary ink tank, and a third selector valve connected to the second selector valve and the second primary ink tank configured to either return the light-colored ink from the print heads to the second primary ink tank or to direct the dark-colored ink to the second selector valve.

Abstract: The disclosure is directed to an Echo-Planar-Imaging (EPI) magnetic resonance imaging techniques combined with a variable-density undersampling scheme. The technique comprises generating an RF pulse, applying a switched frequency-encoding read out gradient in a variable time interval, and applying simultaneously an intermittently blipped low-magnitude phase-encoding gradient with a variable value of an integral of the phase-encoding gradient. The aforementioned steps are carried out such that the k-space is at least partially undersampled and the time interval of one read out gradient is varied depending on the integral of the phase encoding gradient, such that a ratio between the variable time interval of the read out gradient and the integral of the corresponding phase encoding gradient is kept above or at a predetermined constant value, which is related to a predetermined criteria of image quality.

Abstract: Methods, systems, and devices related to a printer system that includes a first primary ink tank holding a dark-colored ink, a second primary ink tank holding a light-colored ink, a first selector valve configured to change a state, a first secondary ink tank connected to the first primary ink tank via the first selector valve, a second secondary ink tank connected to the first and second primary ink tanks via the first selector valve, a second selector valve connected to the first primary ink tank configured to return the dark-colored ink from the print heads to the first primary ink tank, and a third selector valve connected to the second selector valve and the second primary ink tank configured to either return the light-colored ink from the print heads to the second primary ink tank or to direct the dark-colored ink to the second selector valve.

Abstract: Methods, systems, and devices related to a printer system that includes a first primary ink tank holding a dark-colored ink, a second primary ink tank holding a light-colored ink, a first selector valve configured to change a state, a first secondary ink tank connected to the first primary ink tank via the first selector valve, a second secondary ink tank connected to the first and second primary ink tanks via the first selector valve, a second selector valve connected to the first primary ink tank configured to return the dark-colored ink from the print heads to the first primary ink tank, and a third selector valve connected to the second selector valve and the second primary ink tank configured to either return the light-colored ink from the print heads to the second primary ink tank or to direct the dark-colored ink to the second selector valve.

Abstract: The present invention relates to bi-specific antigen binding molecules and associated fusion proteins and conjugates. In particular, the present invention relates to bi-specific antigen binding molecules with specificity for both receptor tyrosine kinase-like orphan receptor 1 (ROR1) and epidermal growth factor receptor (EGFR) and associated fusion proteins and conjugates. In a further aspect, the present invention relates to conjugated immunoglobulin-like shark variable novel antigen receptors (VNARs).

Abstract: The disclosed embodiments include a system for generating a unitary structure with a three-dimensional (3D) printing process. The unitary structure includes a cavity configured to contain a fluid and a passageway configured to route the fluid to or from the cavity.

Abstract: Methods, systems, and devices related to a printer system that includes a first primary ink tank holding a dark-colored ink, a second primary ink tank holding a light-colored ink, a first selector valve configured to change a state, a first secondary ink tank connected to the first primary ink tank via the first selector valve, a second secondary ink tank connected to the first and second primary ink tanks via the first selector valve, a second selector valve connected to the first primary ink tank configured to return the dark-colored ink from the print heads to the first primary ink tank, and a third selector valve connected to the second selector valve and the second primary ink tank configured to either return the light-colored ink from the print heads to the second primary ink tank or to direct the dark-colored ink to the second selector valve.

Abstract: Edge hold down (EHD) systems are described herein that enable high print quality to be achieved more consistently, particularly when using substrates that are rigid or include one or more defects. Each EHD system includes a tensioned band for holding down an edge of a substrate as it passes through a printer assembly without impacting the print area. The tensioned band can be affixed between an entry tension assembly and an exit tension assembly disposed downstream of the entry tension assembly in the media feed direction. The tensioned band holds the substrate substantially flat against a transfer belt during printing by applying pressure to the surface of the substrate. The tensioned band generally contacts the surface of the substrate substantially proximate to an outer edge that is parallel to the media feed direction.

Abstract: Methods, systems, and devices related to a printer system that includes a first primary ink tank holding a dark-colored ink, a second primary ink tank holding a light-colored ink, a first selector valve configured to change a state, a first secondary ink tank connected to the first primary ink tank via the first selector valve, a second secondary ink tank connected to the first and second primary ink tanks via the first selector valve, a second selector valve connected to the first primary ink tank configured to return the dark-colored ink from the print heads to the first primary ink tank, and a third selector valve connected to the second selector valve and the second primary ink tank configured to either return the light-colored ink from the print heads to the second primary ink tank or to direct the dark-colored ink to the second selector valve.

Abstract: Methods, systems, and devices related to a printer system that includes a first primary ink tank holding a dark-colored ink, a second primary ink tank holding a light-colored ink, a first selector valve configured to change a state, a first secondary ink tank connected to the first primary ink tank via the first selector valve, a second secondary ink tank connected to the first and second primary ink tanks via the first selector valve, a second selector valve connected to the first primary ink tank configured to return the dark-colored ink from the print heads to the first primary ink tank, and a third selector valve connected to the second selector valve and the second primary ink tank configured to either return the light-colored ink from the print heads to the second primary ink tank or to direct the dark-colored ink to the second selector valve.

Abstract: The present invention relates to the formation of multi-domain specific binding molecules comprising VNARs. Specific binding domains that bind to Tumour Necrosis Factor alpha (TNF?) are also provided.

Abstract: Various implementations include wearable audio devices and related methods for controlling such devices. In some particular implementations, a computer-implemented method of controlling a wearable audio device configured to provide an audio output includes: receiving data indicating the wearable audio device is proximate a geographic location associated with a localized audio message; providing a prompt to initiate playback of the localized audio message to a user of the wearable audio device; and initiating playback of the localized audio message at the wearable audio device in response to actuation of the prompt by the user.

Abstract: Techniques for visual transformation using a motion profile are described. According to one or more implementations, motion profiles are utilized that describe known motion patterns for different display devices. A motion profile for a particular display device, for example, can be leveraged for visually transforming visual objects that are displayed on the display device.

Abstract: The disclosed embodiments include a system for generating a unitary structure with a three-dimensional (3D) printing process. The unitary structure includes a cavity configured to contain a fluid and a passageway configured to route the fluid to or from the cavity.