Patents by Inventor Andrew R. Hudson

Andrew R. Hudson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Radiopharmaceuticals Targeting Somatostatin Receptor 2 and Uses Thereof
    Publication number: 20250222146
    Abstract: Provided herein are peptides and conjugates (e.g., radiopharmaceutical conjugates) having avidity for a somatostatin receptor and uses thereof. The conjugate can comprise a 6-mer peptide, such as a monocyclic 6-mer peptide, a metal chelator, and optionally a linker connecting the peptide to the chelator. The radiopharmaceutical conjugate can further comprise a radionuclide bound to the metal chelator. Further provided herein are methods of preparing the conjugates, and methods of treating cancer by administering the described conjugates to a subject in need thereof.
    Type: Application
    Filed: December 20, 2024
    Publication date: July 10, 2025
    Applicant: RayzeBio, Inc.
    Inventors: Abhijit Bhat, Nicholas D. Smith, Nicole Bakas, Alain Noncovich, Andrew R. Hudson, Joe Anh Tran, Patrick Napier, Yalda Bravo
  • HSD17B13 INHIBITORS AND USES THEREOF
    Publication number: 20240368127
    Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.
    Type: Application
    Filed: September 14, 2022
    Publication date: November 7, 2024
    Inventors: Johnny Y. Nagasawa, Iriny Botrous, Andiliy G. Lai, Andrew R. Hudson, Nicholas D. Smith, Steven P. Govek
  • HSD17B13 INHIBITORS AND USES THEREOF
    Publication number: 20240083853
    Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.
    Type: Application
    Filed: September 29, 2021
    Publication date: March 14, 2024
    Inventors: Steven P. Govek, Andiliy G. Lai, Andrew R. Hudson, Nicholas D. Smith, Karensa L. Fasanya
  • HSD17B13 INHIBITORS AND USES THEREOF
    Publication number: 20240083861
    Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.
    Type: Application
    Filed: September 29, 2021
    Publication date: March 14, 2024
    Inventors: Andrew R. Hudson, Steven P. Govek, Johnny Y. Nagasawa, Iriny Botrous, Nicholas D. Smith, Karensa L. Fasanya
  • HSD17B13 INHIBITORS AND USES THEREOF
    Publication number: 20240034736
    Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.
    Type: Application
    Filed: September 29, 2021
    Publication date: February 1, 2024
    Inventors: Andrew R. Hudson, Steven P. Govek, Johnny Y. Nagasawa, Iriny Botrous, Nicholas D. Smith, Karensa L. Fasanya
  • Methods and compositions associated with the granulocyte colony-stimulating factor receptor
    Patent number: 11413274
    Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: August 16, 2022
    Assignee: Ligand Pharmaceuticals, Inc.
    Inventors: Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelis Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
  • SSAO INHIBITORS AND USES THEREOF
    Publication number: 20220002309
    Abstract: Described herein are compounds that are semicarbazide-sensitive amine oxidase (SSAO) inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating or preventing a liver disease or condition.
    Type: Application
    Filed: October 23, 2019
    Publication date: January 6, 2022
    Inventors: Nicholas D. SMITH, Andrew R. HUDSON, Mi CHEN, Johnny Y. NAGASAWA, Iriny BOTROUS
  • METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR
    Publication number: 20210046045
    Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.
    Type: Application
    Filed: July 10, 2020
    Publication date: February 18, 2021
    Inventors: Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelis Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
  • Methods and compositions associated with the granulocyte colony-stimulating factor receptor
    Patent number: 10736875
    Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: August 11, 2020
    Assignee: LIGAND PHARMACEUTICALS, INC.
    Inventors: Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelis Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
  • SSAO INHIBITORS AND USES THEREOF
    Publication number: 20200181104
    Abstract: Described herein are compounds that are semicarbazide-sensitive amine oxidase (SSAO) inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating or preventing a liver disease or condition.
    Type: Application
    Filed: February 14, 2020
    Publication date: June 11, 2020
    Inventors: Nicholas D. Smith, Andrew R. Hudson, Mi Chen, Johnny Y. Nagasawa, Iriny Botrous
  • METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR
    Publication number: 20180369197
    Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.
    Type: Application
    Filed: September 10, 2018
    Publication date: December 27, 2018
    Inventors: Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelius Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
  • Methods and compositions associated with the granulocyte colony-stimulating factor receptor
    Patent number: 10111859
    Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.
    Type: Grant
    Filed: August 25, 2016
    Date of Patent: October 30, 2018
    Assignee: LIGAND PHARMACEUTICALS, INC.
    Inventors: Lin Zhi, Andrew R. Hudson, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelius Arjan van Oeveren, Lino J. Valdez
  • Hematopoietic growth factor mimetic small molecule compounds and their uses
    Patent number: 9622991
    Abstract: The present embodiments relate to compounds with physiological effects, such as the activation of hematopoietic growth factor receptors. The present embodiments also relate to use of the compounds to treat a variety of conditions, diseases and ailments such as hematopoietic conditions and disorders.
    Type: Grant
    Filed: May 15, 2015
    Date of Patent: April 18, 2017
    Assignee: Ligand Pharmaceuticals Inc.
    Inventors: Lin Zhi, Andrew R. Hudson, Cornelis A. Van Oeveren, Steven L. Roach, Bijan Pedram, Yixing Shen, Lino J. Valdez, Jillian Basinger, Virginia Heather Sharron Grant, Jason C. Pickens
  • METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR
    Publication number: 20160374989
    Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.
    Type: Application
    Filed: August 25, 2016
    Publication date: December 29, 2016
    Inventors: Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, Cornelius Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
  • Methods and compositions associated with the granulocyte colony-stimulating factor receptor
    Patent number: 9492430
    Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.
    Type: Grant
    Filed: November 12, 2012
    Date of Patent: November 15, 2016
    Assignee: Ligand Pharmaceuticals, Incorporated
    Inventors: Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, C. Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
  • Hematopoietic growth factor mimetic small molecule compounds and their uses
    Patent number: 9144557
    Abstract: The present embodiments relate to compounds with physiological effects, such as the activation of hematopoietic growth factor receptors. The present embodiments also relate to use of the compounds to treat a variety of conditions, diseases and ailments such as hematopoietic conditions and disorders.
    Type: Grant
    Filed: October 12, 2010
    Date of Patent: September 29, 2015
    Assignee: Ligand Pharmaceuticals Inc.
    Inventors: Lin Zhi, Andrew R Hudson, Cornelis A. Van Oeveren, Steven L. Roach, Bijan Pedram, Yixing Shen, Lino J. Valdez, Jillian Basinger, Virginia Heather Sharron Grant, Jason C. Pickens
  • HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES
    Publication number: 20150252043
    Abstract: The present embodiments relate to compounds with physiological effects, such as the activation of hematopoietic growth factor receptors. The present embodiments also relate to use of the compounds to treat a variety of conditions, diseases and ailments such as hematopoietic conditions and disorders.
    Type: Application
    Filed: May 15, 2015
    Publication date: September 10, 2015
    Inventors: Lin Zhi, Andrew R. Hudson, Cornelis A. Van Oeveren, Steven L. Roach, Bijan Pedram, Yixing Shen, Lino J. Valdez, Jillian Basinger, Virginia Heather Sharron Grant, Jason C. Pickens
  • METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR
    Publication number: 20140296292
    Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.
    Type: Application
    Filed: November 12, 2012
    Publication date: October 2, 2014
    Inventors: Lin Zhi, Keith Marschke, Virginia H. Grant, Steven L. Roach, Yixing Shen, Jason C. Pickens, Bijan Pedram, C. Arjan van Oeveren, Lino J. Valdez, Andrew R. Hudson
  • USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS
    Publication number: 20140243324
    Abstract: The present invention relates to uses of small molecule mimetics of hematopoietic growth factors. In particular the present invention relates to uses of small molecule mimetics of erythropoietin.
    Type: Application
    Filed: November 17, 2011
    Publication date: August 28, 2014
    Applicant: LIGAND PHARMACEUTICALS INCORPORATED
    Inventors: Reid P. Bissonnette, Andrew R. Hudson, Keith B. Marschke, Deepa Rungta, Lin Zhi
  • Small molecule hematopoietic growth factor mimetic compounds that activate hematopoietic growth factor receptors
    Patent number: 8680150
    Abstract: The present embodiments relate to compounds with physiological effects, such as the activation of hematopoietic growth factor receptors. The present embodiments also relate to use of the compounds to treat a variety of conditions, diseases and ailments such as hematopoietic conditions and disorders.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: March 25, 2014
    Assignee: Ligand Pharmaceuticals, Inc.
    Inventors: Lin Zhi, Andrew R. Hudson, Cornelis A. Van Oeveren, Steven L. Roach, Jason C. Pickens, Yixing Shen, Catalina Cuervo, Lino J. Valdez, Jillian Basinger, Virgina H. Grant