Abstract: Methods of detecting target molecules using electrophoresis and media containing immobilized capture are described.

Abstract: Methods of detecting target molecules using electrophoresis and media containing immobilized capture are described.

Abstract: Disclosed are devices and methods for the storage, shipment, moving and/or transferring, mixing, reacting, isolation, conditioning, lyophilization, stabilization, metering, dispensing, detecting, manipulation and management of materials, particularly solids, powders and liquids. Each such device or method provides a means of storing one or more quantities of one or more materials in one or more reservoirs, optionally protecting said quantities from air, moisture or light. Optionally, multiple such reservoirs may be placed or arranged in ensembles such as in arrays or other physical patterns, optionally providing for the simultaneous, parallel or rapid access to more than one such reservoir at once.

Abstract: This invention features methods, apparatus and kits for performing nucleic acid hybridization and amplification reactions on a support. Such methods and apparatus are useful in diagnostic and therapeutic processes for synthesizing nucleic acid and detecting target nucleic acids in a sample.

Abstract: Methods for determining the presence of a target polynucleotide sequence using chemical hybridization in sequential probe and displacement complex formation with potential for signal gain prior to detection are disclosed.

Abstract: Devices and methods for detecting the presence, or absence of the presence of at least one target molecule employing a receptacle housing a reaction chamber comprised of at least one compartment containing suitable reagents for the detection of the target molecule are disclosed.

Abstract: This invention features methods, apparatus and kits for performing nucleic acid hybridization and amplification reactions on a support. Such methods and apparatus are useful in diagnostic and therapeutic processes for synthesizing nucleic acid and detecting target nucleic acids in a sample.

Abstract: An apparatus for automatically scaling an X-Y recorder for use with a thermal analyser wherein temperature range span during an experiment may be plotted exactly scaled to an abscissa such that the left side of the graphical representation corresponds exactly to the minimum temperature during the experiment and the right side of the representation corresponds exactly to the maximum temperature achieved.

Abstract: A system for use in thermal analysis for correcting discrepancies between oven temperature and desired sample temperature including means for automatically calibrating the system at several selected points in the analytical temperature scale wherein actual sample temperature is forced to agree exactly with desired sample temperature by appropriately changing oven temperature and wherein the calibrated sample temperature and the difference between oven temperature and sample temperature at the several points are used to correct for discrepancies throughout the intervening analytical temperature scale.

Abstract: Anticipation signals are derived for each peak whenever a differential exists within a closed loop having the electrical output connected to the input thereof and a confirmation signal is derived after each peak at a threshold level of the new slope polarity exceeding the noise level of the electrical output. The amplitude of each peak is stored as a voltage level which follows the electrical output throughout either slope polarity until a peak is reached and this voltage level is continuously compared with the electrical output to derive the slope polarity thresholds. Otherwise, a very particular embodiment is disclosed with which the stored voltage level only relates to either the most significant maximum or minimum peak of the electrical output and the disclosed embodiments are related to instruments which perform spectral analysis.