Abstract: A pH sensor for a single-use container includes a plunger sleeve configured to couple to a flange of the single-use container. A plunger is axially movable within the plunger sleeve between a storage position and an operating position. A pH sensing element coupled to the plunger wherein the pH element is disposed within a storage chamber in the storage position and is configured to be exposed to an interior of the single-use container in the operating position. In one example, a temperature sensitive element is disposed within the pH sensor and configured to sense temperature proximate the pH sensing element. In another example, a lock member is coupled to the plunger, where the lock member has a locked position and an unlocked position, the lock member being configured to inhibit movement of the plunger when in the locked position. In yet another example, the plunger includes at least one filling channel that allows access to a reference fill chamber when the plunger is in a filling position.

Abstract: A process fluid connector for a single-use process fluid sensing system is provided. The process fluid connector includes a pair of process fluid connections, each process fluid connection being configured to couple to a cooperative process fluid coupling. A process fluid conduit section is operably coupled to each of the process fluid connections. A sensor attachment port is coupled to the process fluid conduit section and is configured to receive and mount a process fluid sensor. A retractable fluid chamber is coupled to the process fluid conduit section and configured to provides wet storage for sensing component(s) of the process fluid sensor. A process fluid sensing system using the process fluid connector is also provided.

Abstract: A single-use electrochemical analytical sensor is provided. The sensor includes a sensing electrode configured to contact process fluid and a reference chamber containing an electrolyte. A reference electrode is disposed in the electrolyte. A reference junction is configured to contact the process fluid and is further configured to generate a flow of electrolyte into the process fluid. The reference chamber is configured to be stored in a depressurized state and then pressurized prior to operation. A method of operating a single-use electrochemical sensor is also provided.

Abstract: A pH sensor for a single-use container includes a plunger sleeve configured to couple to a flange of the single-use container. A plunger is axially movable within the plunger sleeve between a storage position and an operating position. A pH sensing element coupled to the plunger wherein the pH element is disposed within a storage chamber in the storage position and is configured to be exposed to an interior of the single-use container in the operating position. In one example, a temperature sensitive element is disposed within the pH sensor and configured to sense temperature proximate the pH sensing element. In another example, a lock member is coupled to the plunger, where the lock member has a locked position and an unlocked position, the lock member being configured to inhibit movement of the plunger when in the locked position. In yet another example, the plunger includes at least one filling channel that allows access to a reference fill chamber when the plunger is in a filling position.

Abstract: A pH sensor for a single-use container includes a plunger sleeve configured to couple to a flange of the single-use container. A plunger is axially movable within the plunger sleeve between a storage position and an operating position. A pH sensing element coupled to the plunger wherein the pH element is disposed within a storage chamber in the storage position and is configured to be exposed to an interior of the single-use container in the operating position. In one example, a temperature sensitive element is disposed within the pH sensor and configured to sense temperature proximate the pH sensing element. In another example, a lock member is coupled to the plunger, where the lock member has a locked position and an unlocked position, the lock member being configured to inhibit movement of the plunger when in the locked position. In yet another example, the plunger includes at least one filling channel that allows access to a reference fill chamber when the plunger is in a filling position.

Abstract: An interface for coupling a dissolved oxygen sensor to a single-use bioreactor container is provided. A dissolved oxygen (DO) window membrane is operably coupled to the single-use container and configured to position a DO sensor at least partially within the single-use container. In some embodiments, a DO window body mounts the DO window membrane at a distal end thereof. The DO window body can include a slide lock for facilitating positioning of a DO sensor within the DO window body. Additionally, the DO window body may include at least one heat exchange fin.

Abstract: A pH sensor for a single-use container includes a plunger sleeve configured to couple to a flange of the single-use container. A plunger is axially movable within the plunger sleeve between a storage position and an operating position. A pH sensing element coupled to the plunger wherein the pH element is disposed within a storage chamber in the storage position and is configured to be exposed to an interior of the single-use container in the operating position. In one example, a temperature sensitive element is disposed within the pH sensor and configured to sense temperature proximate the pH sensing element. In another example, a lock member is coupled to the plunger, where the lock member has a locked position and an unlocked position, the lock member being configured to inhibit movement of the plunger when in the locked position. In yet another example, the plunger includes at least one filling channel that allows access to a reference fill chamber when the plunger is in a filling position.