Abstract: The present invention relates to compounds of formula I: wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt or solvate thereof. The compounds of formula I are inhibitors of aurora kinase and/or FLT3. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which aurora kinase and/or FLT3 activity is implicated.

Abstract: The present invention relates to compounds of formula I: wherein R1 and R2 are as defined herein, or a pharmaceutically acceptable salt or solvate thereof. The compounds of formula I are inhibitors of aurora kinase and/or FLT3. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which aurora kinase and/or FLT3 activity is implicated.

Abstract: An improved continuous cyclic process for removing oxides of sulfur from a waste gas with a regenerable particulate adsorbent in which hot adsorbent particles pick up SOx in a first fluid transport riser, followed by separation of clean gas from sulfur-contained particles which are then recycled to a desorber in which they are contacted at elevated temperature with a mixture of reducing gas and water vapor for release of sulfur as hydrogen sulfide. The adsorbent particles are then recycled in the process. Means are provided for removing particulates in the waste gas.

Abstract: Coke or coke and hydrogen production may increase when the Asphalt Residual Treating (ART) Process for removing metallic and carbonaceous contaminants from hydrocarbons is operated with feed stock containing impurities that result in the deposition on the solid particulate contact material of acidic metallic compounds such as heavy metal chlorides. Coke or coke and hydrogen production is reduced by charging ammonia or other fugitive basic nitrogen compounds to the system after burning coke from the circulating inventory of catalytically inert contact material and prior to selectively vaporizing incoming charge of feed stock in the presence of the hot regenerated contact material.