Patents by Inventor Andrew Simons

Andrew Simons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11021135
    Abstract: A system includes a processor configured to wirelessly communicate with a mobile device application. The processor is further configured to receive a vehicle-command from the mobile device application and send a wireless instruction to a vehicle instructing an action corresponding to and responsive to the received vehicle command.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: June 1, 2021
    Assignee: Ford Global Technologies, LLC
    Inventors: David Martin Gersabeck, David Anthony Hatton, Ziad Alhihi, Michael Andrew Simons, Thomas Nelson, Ryan Conroy
  • Publication number: 20200339586
    Abstract: This invention provides compounds of formula (I) and salts thereof, which have activity as inhibitors of N-myristoyl transferase (NMT). The invention also relates to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of N-myristoyl transferase provides a therapeutic or prophylactic effect, including protozoan infections (such as malaria and leishmaniasis), viral infections (such as human rhinovirus and HIV), and hyperproliferative disorders (such as B-cell lymphoma).
    Type: Application
    Filed: July 8, 2020
    Publication date: October 29, 2020
    Applicant: Imperial College Innovations Limited
    Inventors: Andrew Simon Bell, Edward William Tate, Robin John Leatherbarrow, Jennie Ann Hutton, James Antony Brannigan
  • Patent number: 10759804
    Abstract: This invention provides compounds of formula (I) and salts thereof, which have activity as inhibitors of N-myristoyl transferase (NMT). The invention also relates to uses of such compounds as medicaments, in particular in the treatment of a disease or disorder in which inhibition of N-myristoyl transferase provides a therapeutic or prophylactic effect, including protozoan infections (such as malaria and leishmaniasis), viral infections (such as human rhinovirus and HIV), and hyperproliferative disorders (such as B-cell lymphoma).
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: September 1, 2020
    Assignee: IMPERIAL COLLEGE INNOVATIONS LIMITED
    Inventors: Andrew Simon Bell, Edward William Tate, Robin John Leatherbarrow, Jennie Ann Hutton, James Antony Brannigan
  • Patent number: 10744954
    Abstract: An entertainment display system for use within vehicles such as aircraft or buses. Systems of the inventive subject matter include a base component forming a basin with a fixed angle frame coupled with the basin. The system can then be installed into the bottom surface of an overhead storage compartment or the like. Methods of the inventive subject matter include steps required to install the system into a vehicle.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: August 18, 2020
    Assignee: Systems and Software Enterprises, LLC
    Inventors: Eric P. Moyer, Samuel A. Carswell, Brian Andrew Simone
  • Patent number: 10745401
    Abstract: The present invention relates to a medicament for treating neuropsychiatric diseases, comprising a compound of Formula (1): or a pharmaceutically acceptable salt thereof, as an active ingredient.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: August 18, 2020
    Assignee: SUMITOMO DAINIPPON PHARMA CO., LTD.
    Inventors: Hidefumi Yoshinaga, Yohei Ikuma, Junya Ikeda, Satoshi Adachi, Harunobu Mitsunuma, Yoshinori Aihara, Jeremy Besnard, Andrew Simon Bell
  • Publication number: 20200255432
    Abstract: The present invention relates to a medicament for treating neuropsychiatric diseases, comprising a compound of Formula (1): or a pharmaceutically acceptable salt thereof, as an active ingredient.
    Type: Application
    Filed: July 22, 2019
    Publication date: August 13, 2020
    Applicant: Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Hidefumi YOSHINAGA, Yohei IKUMA, Junya IKEDA, Satoshi ADACHI, Harunobu MITSUNUMA, Yoshinori AIHARA, Jeremy BESNARD, Andrew Simon BELL
  • Patent number: 10737634
    Abstract: Display systems for a vehicle are contemplated that comprise a seat display unit coupled with a display screen, where the display screen is affixed to a seat back and the seat display unit is disposed within the seat back. The display screen is fixed to the seat back such that its relative position with the seat back remains constant when the seat back is reclined. The seat display unit is coupled to the seat back, such that the seat display unit automatically tilts or pivots when the seat back is reclined, and while the display screen does not move relative to the seat back.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: August 11, 2020
    Assignee: Systems and Software Enterprises, LLC
    Inventors: Romain Claude Andre Lecomte, Brian Andrew Simone, Samuel A. Carswell, Steve B. Sargeant
  • Publication number: 20200225128
    Abstract: It has surprisingly been discovered that it is possible to stabilise biomolecules such as RNA, DNA and proteins in biological samples such as cells, tissues, biopsies and blood using deep eutectic solvents (DES). It has also been discovered that DES mixtures can be used to fix and preserve cell morphology in biological samples such as tissue blocks, cancer biopsies and whole blood. This invention describes methods to stabilise and preserve biomolecules, whole cells, tissues, blood and biological samples using DES mixtures.
    Type: Application
    Filed: January 17, 2020
    Publication date: July 16, 2020
    Inventors: Andrew Simon Goldsborough, Malcom Robert Bates
  • Publication number: 20200211828
    Abstract: A plasma processing apparatus for processing a substrate using a plasma, comprising: a process chamber in which the processing takes place; a plasma source for providing a plasma to the process chamber; a substrate mount within the process chamber for holding the substrate, the substrate mount comprising a surface having a plurality of apertures.
    Type: Application
    Filed: June 13, 2018
    Publication date: July 2, 2020
    Inventors: Andrew Simon Hall Brooks, Gareth Hennighan, Gianfranco Aresta, Richard Anthony Lione, Shailendra Vikram Singh, Siobhan Marie Woollard
  • Patent number: 10688963
    Abstract: A vehicle that includes in-vehicle controller(s) coupled to an external network transceiver, and configured to register a key fob and/or a mobile device configured as a key fob. The transceiver is configured to communicate autonomously with remote servers to respond to a key fob signal received from the server, which includes an authentication code and a remote control command generated by the key fob and/or mobile device configured as the key fob. In further variations, the key fob is also configured to be paired and/or registered by an external mobile device, by the authentication code, and to generate the remote control command via the mobile device. In response to the key fob signal, the controller(s) autonomously adjust vehicle systems, such as locking or unlocking, arming and disarming a security system, adjusting cabin and/or seat temperature and configuration preferences, as well as other driver vehicle preferences.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: June 23, 2020
    Assignee: Ford Global Technologies, LLC
    Inventors: David Anthony Hatton, David Marvin Gersabeck, Thomas Nelson, Michael Andrew Simons, Ziad Alhihi, Ryan Conroy
  • Publication number: 20200172543
    Abstract: The present invention relates to a medicament for treating neuropsychiatric diseases, comprising a compound of Formula (1): or a pharmaceutically acceptable salt thereof, as an active ingredient.
    Type: Application
    Filed: February 10, 2020
    Publication date: June 4, 2020
    Applicant: Sumitomo Dainippon Pharma Co., Ltd.
    Inventors: Hidefumi YOSHINAGA, Yohei IKUMA, Junya IKEDA, Satoshi ADACHI, Harunobu MITSUNUMA, Yoshinori AIHARA, Jeremy BESNARD, Andrew Simon BELL
  • Publication number: 20200123158
    Abstract: The present invention relates to novel compounds and pharmaceutically acceptable salts or solvates thereof which have activity as inhibitors of Schistosoma growth. The invention also relates to pharmaceutical compositions comprising such compounds, salts or solvates and to the use of such compounds as medicaments, in particular in the treatment or prevention of schistosomiasis, also known as bilharzia.
    Type: Application
    Filed: January 15, 2018
    Publication date: April 23, 2020
    Inventors: John Mark Francis Gardner, Andrew Simon Bell
  • Patent number: 10623122
    Abstract: System and methods are described for automatic pairing a plurality of devices within a vehicle. Based on a seat mapping stored within a server, a seat display unit and its allocated peripherals can be paired in sequence, one-by-one. Thus, a first seat display unit and its allocated peripherals can be powered on. Then, the peripherals can be paired with the first seat display unit, and the first seat display unit and the allocated peripherals can be powered down. Once this is complete, the next seat display unit and its allocated peripherals can be powered on, paired, and then powered down before continuing in sequence until all peripherals are paired with their allocated seat display units.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: April 14, 2020
    Assignee: Systems and Software Enterprises, LLC
    Inventors: Matthew Gledich, Romain Lecomte, Samuel A. Carswell, Brian Andrew Simone
  • Patent number: 10577363
    Abstract: The present disclosure provides substituted piperidine compounds having Formula (I), and the pharmaceutically acceptable salts and solvates thereof, wherein R1, B, X, and Z are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of SMYD proteins such as SMYD3 or SMYD2. Compounds of the present disclosure are especially useful for treating cancer.
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: March 3, 2020
    Assignee: EPIZYME, INC.
    Inventors: Lorna Helen Mitchell, Andrew Simon Bell, Richard Chesworth, Megan Alene Cloonan Foley, Kevin Wayne Kuntz, James Edward John Mills, Michael John Munchhof
  • Patent number: 10539488
    Abstract: It has surprisingly been discovered that it is possible to stabilize biomolecules such as RNA, DNA and proteins in biological samples such as cells, tissues, biopsies and blood using deep eutectic solvents (DES). It has also been discovered that DES mixtures can be used to fix and preserve cell morphology in biological samples such as tissue blocks, cancer biopsies and whole blood. This invention describes methods to stabilize and preserve biomolecules, whole cells, tissues, blood and biological samples using DES mixtures.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: January 21, 2020
    Assignee: RNASSIST LTD.
    Inventors: Andrew Simon Goldsborough, Malcolm Robert Bates
  • Publication number: 20190344307
    Abstract: A method for depositing a protective coating onto a substrate, wherein the protective coating comprises (i) a moisture-barrier layer which is in contact with the substrate and which comprises a first sub-layer, optionally one or more intermediate sub-layers, and a final sub-layer, (ii) a mechanical-protective layer which is inorganic, and (iii) a gradient layer interposing the moisture-barrier layer and the mechanical-protective layer.
    Type: Application
    Filed: December 12, 2017
    Publication date: November 14, 2019
    Inventors: Shailendra Vikram Singh, Gianfranco Aresta, Andrew Simon Hall Brooks, Siobhan Marie Woollard, Gareth Hennighan
  • Patent number: 10428062
    Abstract: The present invention relates to novel geminal substituted aminobenzisoxazole compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of ?7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: October 1, 2019
    Assignee: Axovant Sciences GmbH
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner
  • Patent number: 10393633
    Abstract: It has surprisingly been discovered that it is possible to stabilize biomolecules such as RNA, DNA and proteins in biological samples such as cells, tissues, biopsies and blood using deep eutectic solvents (DES). It has also been discovered that DES mixtures can be used to fix and preserve cell morphology in biological samples such as tissue blocks, cancer biopsies and whole blood. This invention describes methods to stabilize and preserve biomolecules, whole cells, tissues, blood and biological samples using DES mixtures.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: August 27, 2019
    Assignee: RNASSIST LTD.
    Inventors: Andrew Simon Goldsborough, Malcolm Robert Bates
  • Patent number: 10370569
    Abstract: A curable composition for bonding windings or core laminates in an electrical machine is presented. The curable composition includes: (A) about 10 weight percent to about 25 weight percent of a polyfunctional cyanate ester; (B) about 35 weight percent to about 65 weight percent of a first difunctional cyanate ester, or a prepolymer thereof; (C) about 15 weight percent to about 40 weight percent of a second difunctional cyanate ester, or a prepolymer thereof. An associated method is also presented.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: August 6, 2019
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Weijun Yin, Gary William Yeager, Kevin Warner Flanagan, David Andrew Simon, Eugene Pauling Boden, Kathryn Amanda Misner
  • Patent number: 10370370
    Abstract: The present invention relates to novel aminobenzisoxazole compounds, and pharmaceutical compositions of the same, that are suitable as agonists or partial agonists of Alpha7-nAChR, and methods of preparing these compounds and compositions, and the use of these compounds and compositions in methods of maintaining, treating and/or improving cognitive function. In particular, methods of administering the compound or composition to a patient in need thereof, for example a patient with a cognitive deficiency and/or a desire to enhance cognitive function, that may derive a benefit therefrom.
    Type: Grant
    Filed: June 9, 2016
    Date of Patent: August 6, 2019
    Assignee: Axovant Sciences GmbH
    Inventors: Raksha Acharya, Duane A. Burnett, Matthew Gregory Bursavich, Andrew Simon Cook, Bryce Alden Harrison, Andrew J. McRiner