Patents by Inventor Andrew Sinclair

Andrew Sinclair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240108645
    Abstract: The present invention relates to a method of treating or preventing DNA damage in a cell or cellular senescence of a cell or induction of the senescence associated secretory phenotype (SASP) in a cell, or for treating or preventing the effects of aging, or for preventing or treating cellular senescence and/or induction of SASP associated with high caloric intake or obesity, or for reducing the side effects of chemotherapy, radiotherapy, corticoid treatment, anti-retroviral treatment, or PPAR? agonist treatment comprising administering an effective amount of an NAD+ agonist.
    Type: Application
    Filed: May 5, 2023
    Publication date: April 4, 2024
    Inventors: Lindsay Edward WU, David Andrew SINCLAIR
  • Patent number: 11789906
    Abstract: Method and systems for preparing and analyzing a DNA sample from a subject are provided herein. Also provided are methods and systems for obtaining, analyzing, and manipulating genomic and proteomic sequence data. In particular, methods and systems provided herein involve transformation of raw genetic or proteomic sequence into a compressed data set and transmission of the compressed data set using a fixed binary encoding scheme capable of compressing the data by up to 75%. An interface is in communication with the compression module and configured to display transmitted genomic and proteomic sequence data.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: October 17, 2023
    Assignee: ARC BIO, LLC
    Inventors: Roberto Olivares-Amaya, David Andrew Sinclair, Alejandro Quiroz-Zarate, Thomas J. Watson, Jr.
  • Publication number: 20230229023
    Abstract: The present invention consists of a set of sunglasses used for locating shark teeth on a beach. The invention takes advantage of the way the human brain generates images in order to make shark teeth stand out on the sand. It does so by blocking out specific wavelengths of light that help to accentuate color differences between the teeth and the underlying beach surface. Shark teeth undergo a change of color after falling out that causes them to be differentiable in shade from sand or sediment. By selectively filtering corresponding shades of light, the present invention causes the teeth to stand out as spots on the sand, significantly increasing the ease of spotting and collecting them. When the wavelengths of light reaching the eye are filtered, the shark teeth ultimately stand out as stark dark areas on the beach.
    Type: Application
    Filed: January 14, 2023
    Publication date: July 20, 2023
    Inventors: Andrew Sinclair, Jospeh J. Sinclair
  • Publication number: 20230149437
    Abstract: The present invention relates to methods of increasing vascular density and/or blood flow in tissue of a subject, and to increasing exercise capacity of a subject, the methods include administering to a subject an effective amount of an agent that elevates SIRTI activity in endothelial cells of the subject, the invention further includes administering an NAD+ agonist or NAD+ precursor to a subject to increase vascular density and/or blood flow. The invention includes compositions comprising the said agent.
    Type: Application
    Filed: January 20, 2023
    Publication date: May 18, 2023
    Inventors: Lindsay Edward Wu, David Andrew Sinclair, Abhirup Das
  • Publication number: 20230124554
    Abstract: Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions
    Type: Application
    Filed: November 28, 2022
    Publication date: April 20, 2023
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Tao Bai, Jean-René Ella-Menye, Hsiang-Chieh Hung, Priyesh Jain, Andrew Sinclair, Harihara Subramanian Sundaram, Yang Li, Peng Zhang
  • Patent number: 11512160
    Abstract: Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: November 29, 2022
    Assignee: University of Washington
    Inventors: Shaoyi Jiang, Tao Bai, Jean-René Ella-Menye, Hsiang-Chieh Hung, Priyesh Jain, Andrew Sinclair, Harihara Subramanian Sundaram, Yang Li, Peng Zhang
  • Publication number: 20220196457
    Abstract: A weight measuring system for weighing an object, the weight measuring system comprising at least one weighing mechanism having a deformable fluid filled chamber, the at least one weighing mechanism operable to receive at least a portion of an object; a sensor unit operable to determine at least one measurable criteria of the fluid filled chamber and provide output sensor data indicative of the measurable criteria, and a processor operable to act upon the output sensor data and, when an object is received by the system, operable to provide weight data indicative of the weight of at least a portion of the object.
    Type: Application
    Filed: May 12, 2020
    Publication date: June 23, 2022
    Inventors: Graham William Rennie, Andrew Sinclair Sherriff
  • Patent number: 11122017
    Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: September 14, 2021
    Assignee: ARC BIO, LLC
    Inventors: David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Thomas J. Watson, Jr., Jason Michael Anderson, Pablo G. Coste
  • Publication number: 20200382477
    Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data.
    Type: Application
    Filed: May 19, 2020
    Publication date: December 3, 2020
    Inventors: David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Thomas J. Watson, JR., Jason Michael Anderson, Pablo G. Coste
  • Publication number: 20200368198
    Abstract: The present invention relates to a method of increasing fertility, or reducing rate of decline in fertility, or restoring fertility, of a female subject, comprising administering to the subject an effective amount of an agent which elevates SIRT2 activity or SIRT2 expression, and to compositions and kits for increasing fertility, or reducing rate of decline in fertility, or restoring fertility.
    Type: Application
    Filed: July 31, 2018
    Publication date: November 26, 2020
    Inventors: Lindsay Edward Wu, David Andrew Sinclair, Hayden A. Homer
  • Publication number: 20200253192
    Abstract: Zwitterionic microgels, zwitterionic microgel assemblies, their formulations and methods for their use.
    Type: Application
    Filed: July 20, 2017
    Publication date: August 13, 2020
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Andrew Sinclair, Mary Elizabeth O'Kelly, Tao Bai, Priyesh Jain
  • Patent number: 10673826
    Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: June 2, 2020
    Assignee: ARC BIO, LLC
    Inventors: David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Thomas J. Watson, Jr., Jason Michael Anderson, Pablo G. Coste
  • Patent number: 10630812
    Abstract: A device for compressing subject data, the device comprises a communication link, the communication link capable of receiving a set of subject data; a compression module, the compression module configured to apply a compression algorithm to the set of subject data, the compression algorithm compressing the set of subject data using a reference string of subject data; and a transmission module, the transmission module configured to transmit the compressed subject data. The device further comprising an encryption module for encrypting the subject data.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: April 21, 2020
    Assignee: ARC BIO, LLC
    Inventors: Jason Michael Anderson, David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Ricardo Godinez-Moreno
  • Patent number: 10518848
    Abstract: Aquatic structures with adjustable buoyancy constructed in part with a vent valve for a buoyancy control device suitable for divers, where the vent valve may be opened by any combination of over-pressure, manual pressure relief or a powered means, where a force to a valve plug is applied by means of a spring that is constrained to prevent entirely lateral and angular movement but in which movement of the plug in the axis of the seat is unconstrained.
    Type: Grant
    Filed: February 13, 2018
    Date of Patent: December 31, 2019
    Assignee: Marine Depth Control Engineering, LLC
    Inventors: Andrew Sinclair, Christopher Webb
  • Publication number: 20190328761
    Abstract: The present invention relates to methods of increasing vascular density and/or blood flow in tissue of a subject, and to increasing exercise capacity of a subject, the methods include administering to a subject an effective amount of an agent that elevates SIRT1 activity in endothelial cells of the subject, the invention further includes administering an NAD+ agonist or NAD+ precursor to a subject to increase vascular density and/or blood flow. The invention includes compositions comprising the said agent.
    Type: Application
    Filed: December 21, 2017
    Publication date: October 31, 2019
    Inventors: Lindsay Edward Wu, David Andrew Sinclair, Abhirup Das
  • Publication number: 20190002625
    Abstract: Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions.
    Type: Application
    Filed: June 2, 2016
    Publication date: January 3, 2019
    Applicant: University of Washington
    Inventors: Shaoyi Jiang, Tao Bai, Jean-René Ella-Menye, Hsiang-Chieh Hung, Priyesh Jain, Andrew Sinclair, Harihara Subramanian Sundaram, Yang Li, Peng Zhang
  • Publication number: 20180170486
    Abstract: Aquatic structures with adjustable buoyancy constructed in part with a vent valve for a buoyancy control device suitable for divers, where the vent valve may be opened by any combination of over-pressure, manual pressure relief or a powered means, where a force to a valve plug is applied by means of a spring that is constrained to prevent entirely lateral and angular movement but in which movement of the plug in the axis of the seat is unconstrained.
    Type: Application
    Filed: February 13, 2018
    Publication date: June 21, 2018
    Inventors: Andrew Sinclair, Christopher Webb
  • Publication number: 20180034784
    Abstract: Systems, devices, and methods for encrypting genetic information are provided herein. Also provided herein are systems, devices, and methods for encrypting compressed genetic data, transmitting encrypted compressed genetic data, and receiving, storing, accessing encrypted compressed genetic data. In some cases, a user interface is in communication with a system or device provided herein.
    Type: Application
    Filed: February 9, 2016
    Publication date: February 1, 2018
    Inventors: David Andrew Sinclair, Alejandro Quiroz-Zarate, Roberto Olivares-Amaya, Thomas J. Watson, JR., Jason Michael Anderson, Pablo G. Coste
  • Publication number: 20170357665
    Abstract: Method and systems for preparing and analyzing a DNA sample from a subject are provided herein. Also provided are methods and systems for obtaining, analyzing, and manipulating genomic and proteomic sequence data. In particular, methods and systems provided herein involve transformation of raw genetic or proteomic sequence into a compressed data set and transmission of the compressed data set using a fixed binary encoding scheme capable of compressing the data by up to 75%. An interface is in communication with the compression module and configured to display transmitted genomic and proteomic sequence data.
    Type: Application
    Filed: November 19, 2015
    Publication date: December 14, 2017
    Inventors: Roberto Olivares-Amaya, David Andrew Sinclair, Alejandro Quiroz-Zarate, Thomas J. Watson, Jr.
  • Patent number: 9793984
    Abstract: A coherent receiver adapted to operate as an Optical Spectrum Analyzer (OSA) includes an optical front end adapted to receive an optical signal and to mix the optical signal with a local laser; a photodetector block coupled to the optical front end and adapted to receive an output of the optical front end and provide an output corresponding to spectral components of the optical signal; and a controller coupled to the optical front end and the photodetector block, wherein the controller is adapted to operate in an OSA mode to sweep the local laser across a portion of optical spectrum to perform an OSA measurement while not performing data demodulation.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: October 17, 2017
    Assignee: Ciena Corporation
    Inventors: Andrew Sinclair, Eric Maniloff