Patents by Inventor Andrew Smaligo

Andrew Smaligo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of carbon-carbon bond fragmentation
    Patent number: 12122730
    Abstract: The present disclosure relates to methods of carbon-carbon bond fragmentation.
    Type: Grant
    Filed: February 24, 2020
    Date of Patent: October 22, 2024
    Assignee: The Regents of the University of California
    Inventors: Ohyun Kwon, Andrew Smaligo
  • MACROCYCLIC COMPOUNDS AND METHODS OF USE
    Publication number: 20240294551
    Abstract: The present disclosure provides compounds useful for the inhibition of KRAS G12D, G12V, G12A, G12S, G13D, Q61H, Q61L or G12C. The compounds have a general Formula I?: wherein the variables of Formula I? are defined herein. This disclosure also provides pharmaceutical compositions comprising the compounds, uses of the compounds, and compositions for treatment of, for example, cancer.
    Type: Application
    Filed: March 25, 2024
    Publication date: September 5, 2024
    Applicant: AMGEN INC.
    Inventors: Ryan Paul Wurz, Yunxiao LI, Primali Vasundera NAVARATNE, Jose M. MEDINA, Ning CHEN, Liping PETTUS, Xiaofen LI, John STELLWAGEN, Kexue LI, Brian Alan LANMAN, Michael M. YAMANO, Wei ZHAO, Benjamin WIGMAN, Fabien EMMETIERE, Albert K. AMEGADZIE, Christopher P. MOHR, Aaron C. SIEGMUND, Rene RAHIMOFF, Zhichen WU, Adriano BAUER, Andrew SMALIGO, Quentin Tercenio, Qingyian Liu, Shon K. Booker
  • METHODS OF CARBON-CARBON BOND FRAGMENTATION
    Publication number: 20220169580
    Abstract: The present disclosure relates to methods of carbon-carbon bond fragmentation.
    Type: Application
    Filed: February 24, 2020
    Publication date: June 2, 2022
    Inventors: Ohyun Kwon, Andrew Smaligo