Abstract: In part, the disclosure relates to a source generating four input clock signals; a phase interpolator (PI) circuit that includes four PI quadrant circuits and a PI bias control circuit, wherein each PI quadrant circuit is configured to: receive, via the source, an input clock signal of the four input clock signals, and generate, based on the input clock signal, a pair of intermediate output clock signals of complementary phases; and a current mode logic (CML) to complementary metal-oxide-semiconductor (CMOS) converter.

Abstract: Compositions and methods for treating lymphoma, in particular. T-cell lymphoma and follicular lymphoma. in a human patient are provided. The methods entail administering to the patient an effective amount of cerdulatinib.

Abstract: The present disclosure relates to methods of treating a malignancy in a subject in need thereof. The method involves administering to the subject a combination therapy comprising: (i) an inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) having the structure of Formula (I) or a pharmaceutically acceptable salt, hydrate, polymorph, or solvates thereof, and (ii) an inhibitor of an anti-apoptotic Bcl-2 family protein, where the combination therapy is administered in an amount effective to treat the malignancy in the subject. Also disclosed are methods of reducing levels of regulatory T cells in a patient suffering from a malignancy, as well as combination therapeutics comprising an inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein (MALT1) having the structure of Formula (I) or a pharmaceutically acceptable salt, hydrate, polymorph, or solvates thereof, and an inhibitor of an anti-apoptotic Bcl-2 family protein.

Abstract: The APPARATUSES, METHODS AND SYSTEMS FOR INSIGHT DISCOVERY AND PRESENTATION FROM STRUCTURED AND UNSTRUCTURED DATA (“IDAP”) provides a platform that, in various embodiments, is configurable to identify, display, and act upon insights derived from large volumes of data. In one embodiment, the IDAP is configurable to determine values and relationships for primal data. Identified relationships may be leveraged to build queries optimized for efficient data access across data volumes. The IDAP may also be configured to identify drivers of global metrics of interest, leverage those drivers to discern the efficacy of media and/or advertising campaigns, and provide recommendations to improve and/or optimize campaign efficacy.

Abstract: The present disclosure relates to methods of treating a malignancy in a subject in need thereof. The method involves administering to the subject a combination therapy comprising: (i) an inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) having the structure of Formula (I) or a pharmaceutically acceptable salt, hydrate, polymorph, or solvates thereof, and (ii) an inhibitor of an anti-apoptotic Bcl-2 family protein, where the combination therapy is administered in an amount effective to treat the malignancy in the subject. Also disclosed are methods of reducing levels of regulatory T cells in a patient suffering from a malignancy, as well as combination therapeutics comprising an inhibitor of mucosa-associated lymphoid tissue lymphoma translocation protein (MALT1) having the structure of Formula (I) or a pharmaceutically acceptable salt, hydrate, polymorph, or solvates thereof, and an inhibitor of an anti-apoptotic Bcl-2 family protein.

Abstract: The present disclosure is directed to the use of a compound of Formula (III) in the treatment of DLBCL.

Abstract: Disclosed herein are methods and uses of cerdulatinib for treating diseases or conditions, including hematological cancers, and combinations of cerdulatinib for treating such diseases or conditions.

Abstract: Compositions and methods for treating lymphoma, in particular, T-cell lymphoma and follicular lymphoma, in a human patient are provided. The methods entail administering to the patient an effective amount of cerdulatinib.

Abstract: Compositions and methods for treating lymphoma, in particular, T-cell lymphoma and follicular lymphoma, in a human patient are provided. The methods entail administering to the patient an effective amount of cerdulatinib.

Abstract: The APPARATUSES, METHODS AND SYSTEMS FOR COMMON KEY IDENTIFICATION IN DISTRIBUTED DATA ENVIRONMENTS (“KEY IDENTIFIER”) provides a platform that, in various embodiments, is configurable to efficiently identify and display top keys for a keyspace (e.g., social media posts, financial data feeds, and/or the like) distributed across a plurality of worker nodes, such as in response to a client request. For example, the KEY IDENTIFIER may be configured to identify a likely set of candidate keys across the keyspace, and to count and rank those candidates. Once identified, top keys may be employed for a variety of applications or end goals, including but not limited to report generation, natural language insights, data (re-)distributing, and/or the like.

Abstract: The APPARATUSES, METHODS AND SYSTEMS FOR EFFICIENT AD-HOC QUERYING OF DISTRIBUTED DATA (“RTC”) provides a platform that, in various embodiments, is configurable to provide fast ad-hoc querying against large volumes of data. In one embodiment, the RTC is configurable to select a subset of fields from raw data in association with a domain and compact the corresponding data. Such packed records may be distributed to one or more worker nodes, which maintain the records and associated indexes. A master server facilitates query processing across the worker nodes.

Abstract: Disclosed herein are methods and uses of cerdulatinib for treating diseases or conditions, including hematological cancers, and combinations of cerdulatinib for treating such diseases or conditions.

Abstract: Disclosed herein are methods and uses of cerdulatinib for treating diseases or conditions, including hematological cancers, and combinations of cerdulatinib for treating such diseases or conditions.

Abstract: The APPARATUSES, METHODS AND SYSTEMS FOR INSIGHT DISCOVERY AND PRESENTATION FROM STRUCTURED AND UNSTRUCTURED DATA (“IDAP”) provides a platform that, in various embodiments, is configurable to identify, display, and act upon insights derived from large volumes of data. In one embodiment, the IDAP is configurable to determine values and relationships for primal data. Identified relationships may be leveraged to build queries optimized for efficient data access across data volumes. The IDAP may also be configured to identify drivers of global metrics of interest, leverage those drivers to discern the efficacy of media and/or advertising campaigns, and provide recommendations to improve and/or optimize campaign efficacy.

Abstract: The APPARATUSES, METHODS AND SYSTEMS FOR COMMON KEY IDENTIFICATION IN DISTRIBUTED DATA ENVIRONMENTS (“KEY IDENTIFIER”) provides a platform that, in various embodiments, is configurable to efficiently identify and display top keys for a keyspace (e.g., social media posts, financial data feeds, and/or the like) distributed across a plurality of worker nodes, such as in response to a client request. For example, the KEY IDENTIFIER may be configured to identify a likely set of candidate keys across the keyspace, and to count and rank those candidates. Once identified, top keys may be employed for a variety of applications or end goals, including but not limited to report generation, natural language insights, data (re-)distributing, and/or the like.

Abstract: Compositions and methods for treating lymphoma, in particular, T-cell lymphoma and follicular lymphoma, in a human patient are provided. The methods entail administering to the patient an effective amount of cerdulatinib.

Abstract: The APPARATUSES, METHODS AND SYSTEMS FOR INSIGHT DISCOVERY AND PRESENTATION FROM STRUCTURED AND UNSTRUCTURED DATA (“IDAP”) provides a platform that, in various embodiments, is configurable to identify, display, and act upon insights derived from large volumes of data. In one embodiment, the IDAP is configurable to determine values and relationships for primal data. Identified relationships may be leveraged to build queries optimized for efficient data access across data volumes. The IDAP may also be configured to identify drivers of global metrics of interest, leverage those drivers to discern the efficacy of media and/or advertising campaigns, and provide recommendations to improve and/or optimize campaign efficacy.

Abstract: Disclosed herein are methods and uses of cerdulatinib for treating diseases or conditions, including hematological cancers, and combinations of cerdulatinib for treating such diseases or conditions.

Abstract: A video encoding and transcoding system comprising a video content display unit that has a platform, a browser and a bandwidth and is adapted to display video content, a storage server that is adapted to receive video content, and a video encoder that is adapted to download video content and transcode video content. The preferred system automatically determines the platform, the browser and the bandwidth of the video content display unit and automatically selects the most optimized video format using real time adaptive bit rate switching in HTML5. A method for encoding and transcoding video content comprising providing a video encoding and transcoding system, visiting a video encoder website, selecting a resolution, uploading a video to a storage server, triggering an encoder, downloading a copy of the video, transcoding the video to a selected resolution, and uploading the video to the storage server.

Abstract: The APPARATUSES, METHODS AND SYSTEMS FOR EFFICIENT AD-HOC QUERYING OF DISTRIBUTED DATA (“RTC”) provides a platform that, in various embodiments, is configurable to provide fast ad-hoc querying against large volumes of data. In one embodiment, the RTC is configurable to select a subset of fields from raw data in association with a domain and compact the corresponding data. Such packed records may be distributed to one or more worker nodes, which maintain the records and associated indexes. A master server facilitates query processing across the worker nodes.