Abstract: The present invention relates to a negative pressure wound closure system and methods for using such a system. Preferred embodiments of the invention facilitate closure of the wound by preferentially contracting to provide for movement of the tissue. Preferred embodiments can utilize tissue securing portions that aid in securing the invention within a wound.

Abstract: A self-programming synthesizer with neuroplastic behavior using variable binding and substitution that, on input of a data n, produces a new algorithm f(n) as well as affects an existing algorithm f(n). The synthesizer comprises at least one bare metal and a plethoral of coprocessors, an inference calculus implemented n reprogrammable logic. The synthesizer may also include a microvisor, analog-to-digital conversion and digital-to-analog outputs for some applications. Additionally, the synthesizer may include an internal or separate external clock frequency generator. The portion of plasticity provided by the inference calculus adds a reconfigurable artificial intelligence. The invention combines dynamic threat detection with direct control of system resources to detect and mitigate threats and anneal the system from cyber attack.

Abstract: A method includes in part, generating an electro-optical frequency map (EOFM) of an active layer of an integrated circuit (IC), retrieving a reference map of the IC, comparing the EOFM of the IC with the reference map to determine whether there is a match between an intensity of an identified region in the EOFM map and an intensity of a corresponding region of the reference map, and detecting one or more hardware trojans in the IC if there is no match. The reference map may be associated with a layout of an IC known not to include hardware trojans. The reference map also may be a second EOFM associated with the IC. Alternatively, the reference map may be generated by applying power to the IC, and applying a clock signal to the IC.

Abstract: Disclosed herein are several embodiments of a negative pressure appliance and methods of using the same in the treatment of wounds. Some embodiments are directed to improved fluidic connectors or suction adapters for connecting to a wound site, for example using softer, kink-free conformable suction adapters.

Abstract: A self-programming synthesizer with neuroplastic behavior using variable binding and substitution that, on input of a data n, produces a new algorithm f(n) as well as affects an existing algorithm f(n). The synthesizer comprises at least one bare metal and a plethoral of coprocessors, an inference calculus implemented n reprogrammable logic. The synthesizer may also include a microvisor, analog-to-digital conversion and digital-to-analog outputs for some applications. Additionally, the synthesizer may include an internal or separate external clock frequency generator. The portion of plasticity provided by the inference calculus adds a reconfigurable artificial intelligence. The invention combines dynamic threat detection with direct control of system resources to detect and mitigate threats and anneal the system from cyber attack.

Abstract: A method includes in part, generating an electro-optical frequency map (EOFM) of an active layer of an integrated circuit (IC), retrieving a reference map of the IC, comparing the EOFM of the IC with the reference map to determine whether there is a match between an intensity of an identified region in the EOFM map and an intensity of a corresponding region of the reference map, and detecting one or more hardware trojans in the IC if there is no match. The reference map may be associated with a layout of an IC known not to include hardware trojans. The reference map also may be a second EOFM associated with the IC. Alternatively, the reference map may be generated by applying power to the IC, and applying a clock signal to the IC.

Abstract: In at least one aspect, a water-sports board is configured to collect environmental data. The water-sports board includes a waterproof sensor housing and, disposed within the housing, one or more sensor(s), processor(s), memory device(s), switch(es), batteries. The sensing device is configured, in a first state, not to store environmental data sensed by the at least one sensor in the at least one physical memory device. The sensing device is configured, in a second state, to store environmental data sensed by the at least one sensor in the at least one physical memory device.

Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:

Abstract: In at least one aspect, a water-sports board is configured to collect environmental data. The water-sports board includes a waterproof sensor housing and, disposed within the housing, one or more sensor(s), processor(s), memory device(s), switch(es), batteries. The sensing device is configured, in a first state, not to store environmental data sensed by the at least one sensor in the at least one physical memory device. The sensing device is configured, in a second state, to store environmental data sensed by the at least one sensor in the at least one physical memory device.

Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:

Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:

Abstract: The invention relates to compounds of Formula I or a pharmaceutically acceptable salt, ester or prodrug thereof:

Abstract: The invention provides compositions and methods for the detection of biological targets, (e.g. nucleic acids and proteins) by nucleic acid templated chemistry, for example, by generating fluorescent, chemiluminescent and/or chromophoric signals.

Abstract: A thrombin receptor antagonist having the formula useful for inhibiting the aggregation of blood platelets. The compounds can be used in a method of acting upon a thrombin receptor which comprises administering a therapeutically effective but non-toxic amount of such compound to a mammal, preferably a human.

Abstract: A thrombin receptor antagonist having the formula 1

Abstract: A computer has at least one adapter card slot for receiving an optional adapter card. A cover plate is rotatable hinged and has open and closed positions. In the closed position, the cover plate covers the adapter card slot and inhibits the insertion or removal of an adapter card. When the cover plate is raised into the open position, a tab on the back of the cover plate is rotated out of the slot of an optical switch, and the optical switch then signals circuitry to remove power and bus signals from the adapter card slot; thereby permitting the adapter card to be removed from or inserted into the slot without removing power to the entire computer. When the cover plate is returned to the closed position, the tab is reinserted into the slot of the optical switch, which in turn signals the circuitry to return power and bus signals to the adapter card slot.