Patents by Inventor Andrew T. Gewirtz

Andrew T. Gewirtz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of treating viral infection with a composition comprising IL-18 and IL-22
    Patent number: 11517611
    Abstract: The present invention is directed to compositions including the cytokines IL-18 and IL-22 or biologically active fragments or variants thereof. In some embodiments, the compositions further include a pharmaceutically acceptable carrier. The compositions can farther include other interleukins such as IL-1?, and IL-1? can be used as a combination therapy with either IL-18 or IL-22 or biologically active fragments or variants thereof.
    Type: Grant
    Filed: April 23, 2020
    Date of Patent: December 6, 2022
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Andrew T. Gewirtz, Benyue Zhang
  • COMPOSITIONS INCLUDING IL-18 AND IL-22 AND THEIR USE IN ANTI-VIRAL THERAPIES
    Publication number: 20200368320
    Abstract: The present invention is directed to compositions including the cytokines IL-18 and IL-22 or biologically active fragments or variants thereof. In some embodiments, the compositions further include a pharmaceutically acceptable carrier. The compositions can farther include other interleukins such as IL-1?, and IL-1? can be used as a combination therapy with either IL-18 or IL-22 or biologically active fragments or variants thereof.
    Type: Application
    Filed: April 23, 2020
    Publication date: November 26, 2020
    Inventors: Andrew T. Gewirtz, Benyue Zhang
  • Compositions including IL-18 and IL-22 and their use in anti-viral therapies
    Patent number: 10646548
    Abstract: The present invention is directed to compositions including the cytokines IL-18 and IL-22 or biologically active fragments or variants thereof. In some embodiments, the compositions further include a pharmaceutically acceptable carrier. The compositions can further include other interleukins such as IL-1?, and IL 1? can be used as a combination therapy with either IL-18 or IL-22 or biologically active fragments or variants thereof.
    Type: Grant
    Filed: October 8, 2014
    Date of Patent: May 12, 2020
    Assignee: Georgia State University Research Foundation, Inc.
    Inventors: Andrew T. Gewirtz, Benyue Zhang
  • TLR5 ligands, therapeutic methods, and compositions related thereto
    Patent number: 9872895
    Abstract: The disclosure relates to antiviral therapeutic methods and related compositions. In certain embodiments, the disclosure relates to methods of treating or preventing a viral infection by administering a pharmaceutical composition comprising a TLR5 ligand, such as a flagellin, to a subject in need thereof.
    Type: Grant
    Filed: September 20, 2011
    Date of Patent: January 23, 2018
    Assignee: Emory University
    Inventors: Andrew T. Gewirtz, Benyue Zhang
  • COMPOSITIONS INCLUDING IL-18 AND IL-22 AND THEIR USE IN ANTI-VIRAL THERAPIES
    Publication number: 20160243195
    Abstract: The present invention is directed to compositions including the cytokines IL-18 and IL-22 or biologically active fragments or variants thereof. In some embodiments, the compositions further include a pharmaceutically acceptable carrier. The compositions can further include other interleukins such as IL-1?, and IL 1? can be used as a combination therapy with either IL-18 or IL-22 or biologically active fragments or variants thereof.
    Type: Application
    Filed: October 8, 2014
    Publication date: August 25, 2016
    Inventors: Andrew T. Gewirtz, Benyue Zhang
  • TLR5 LIGANDS, THERAPEUTIC METHODS, AND COMPOSITIONS RELATED THERETO
    Publication number: 20150165009
    Abstract: The disclosure relates to antiviral therapeutic methods and related compositions. In certain embodiments, the disclosure relates to methods of treating or preventing a viral infection by administering a pharmaceutical composition comprising a TLR5 ligand, such as a flagellin, to a subject in need thereof.
    Type: Application
    Filed: September 20, 2011
    Publication date: June 18, 2015
    Applicant: Emory University
    Inventors: Andrew T. Gewirtz, Benyue Zhang