Abstract: Devices and methods for mixing and preparing therapeutic pellets are described. In one aspect, the present disclosure may include a medical device for mixing and preparing pharmaceuticals. The medical device may include a body sized and shaped to be supported by a human hand. The body may be elastically flexible between a relaxed shape and a flexed shape. In the relaxed shape, the body may form a basin and may be shaped and sized to receive a vessel for mixing or forming the therapeutic pellets. In the flexed shape, the bowl may be configured for controlled pouring of the therapeutic pellets.

Abstract: The invention provided herein includes pharmaceutical compositions comprising a TLR7 agonist having the structure of Formula (A), aluminum-containing particles, and one or more pharmaceutically acceptable excipient. The invention further provides the use of such compositions in the treatment of solid tumors either alone or in combination with one or more additional pharmaceutical compositions.

Abstract: The invention provided herein includes pharmaceutical compositions comprising a TLR7 agonist having the structure of Formula (A), aluminum-containing particles, and one or more pharmaceutically acceptable excipient. The invention further provides the use of such compositions in the treatment of solid tumors either alone or in combination with one or more additional pharmaceutical compositions.

Abstract: A fluid management system and method includes a thermal management system disposed within a housing that includes conduits extending between a source and a destination of a first fluid. The first fluid exchanges heat with cooling devices as the first fluid moves between the source and the destination. A fluid mixture including the first fluid and a second fluid, and an exhaust are generated responsive to the first fluid exchanging heat with the cooling devices. The exhaust directed toward an outlet of the housing. A separator assembly fluidly coupled with and disposed downstream of the thermal management system receives the fluid mixture and separates the first fluid from the second fluid. The first fluid is directed in a first direction out of the separator assembly and the second fluid is directed toward the outlet to be combined with the exhaust.

Abstract: The invention provided herein includes pharmaceutical compositions comprising a TLR7 agonist having the structure of Formula (A), aluminum-containing particles, and one or more pharmaceutically acceptable excipient. The invention further provides the use of such compositions in the treatment of solid tumors either alone or in combination with one or more additional pharmaceutical compositions.

Abstract: An illuminated support stand having a housing with a base and at least one sidewall forming an interior volume. The illuminated support stand also has an upper planar surface with a transparent portion centrally disposed thereon. A light source is disposed beneath the transparent portion within the interior volume of the base. The upper planar surface is configured to support an object, such as a vase thereon with a plurality of light-emitting diodes (LEDs) configured to flash in sequence with an audio input. A plurality of control buttons is disposed on an outer front surface of the housing and is used to operate the illuminated support stand. A wireless transceiver is configured to connect to an external source. A skirt is disposed on a perimeter of the housing and is removably secured thereon.

Abstract: The present disclosure relates to a class of pyrimidine derivatives having immunomodulating properties that act via TLR7 which are useful in the treatment of lung cancer and other respiratory conditions. The present disclosure specifically discloses compounds having the structuree of Formula (I), and pharmaceutically acceptable salts thereof.

Abstract: A fluid management system and method includes a thermal management system disposed within a housing that includes conduits extending between a source and a destination of a first fluid. The first fluid exchanges heat with cooling devices as the first fluid moves between the source and the destination. A fluid mixture including the first fluid and a second fluid, and an exhaust are generated responsive to the first fluid exchanging heat with the cooling devices. The exhaust directed toward an outlet of the housing. A separator assembly fluidly coupled with and disposed downstream of the thermal management system receives the fluid mixture and separates the first fluid from the second fluid. The first fluid is directed in a first direction out of the separator assembly and the second fluid is directed toward the outlet to be combined with the exhaust.

Abstract: A software development platform comprising one or more user-selectable modular units containing a vertical stack of back-end business logic. One or more user-selectable modular units containing domain model components. One or more user-selectable modular units containing front end presentation components. A virtual appliance comprising application-specific logic that includes one or more of the modular units containing the vertical stack of back-end business logic, one or more of the user-selectable modular units containing the domain model components and one or more of the user-selectable modular units containing front end presentation components.

Abstract: The present disclosure relates to a class of pyrimidine derivatives having immunomodulating properties that act via TLR7 which are useful in the treatment of lung cancer and other respiratory conditions.

Abstract: An illuminated support stand having a housing with a base and at least one sidewall forming an interior volume. The illuminated support stand also has an upper planar surface with a transparent portion centrally disposed thereon. A light source is disposed beneath the transparent portion within the interior volume of the base. The upper planar surface is configured to support an object, such as a vase thereon with a plurality of light-emitting diodes (LEDs) configured to flash in sequence with an audio input. A plurality of control buttons is disposed on an outer front surface of the housing and is used to operate the illuminated support stand. A wireless transceiver is configured to connect to an external source. A skirt is disposed on a perimeter of the housing and is removably secured thereon.

Abstract: An information handling system includes a management controller, which in turn includes a device access manager. The device access manager detects a new device within the information handling system, and performs a matching process between properties of the new device and matching criteria for a plurality of drivers in the information handling system. The device access manager also receives matching values from each of the plurality of drivers, and selects one of the drivers in response to the one driver having a highest matching value. The matching process for a driver is ended without a matching value being returned to the device access manager in response to a property of the new device not matching a corresponding matching criteria of the driver.

Abstract: The present invention provides a system and single or multi-functional element device that can be inserted and temporarily placed or implanted into a structure having a lumen or hollow space, such as a subject's abdominal cavity to provide therewith access to the site of interest in connection with minimally invasive surgical procedures. The insertable device may be configured such that the functional elements have various degrees of freedom of movement with respect to orienting the functional elements or elements to provide access to the site from multiple and different orientations/perspectives as the procedure dictates, e.g., to provide multiple selectable views of the site, and may provide a stereoscopic view of the site of interest.

Abstract: A method of for system management, comprising initiating a workflow operating on a processor. Initiating a sub-workflow operating on the processor from the workflow. Electronically reading state data for one or more resources designated by the sub-workflow prior to performing a first logical process of the sub-workflow. Storing the state data in a non-transient data memory. Performing logical processes associated with the sub-workflow using the processor. Restoring the state data for the one or more resources if it is determined that an error has occurred.

Abstract: A method for template derivation comprising generating a plurality of templates using a processor, each template having a plurality of unfixed attributes. The plurality of templates are stored in a non-transient data memory. One of the plurality of templates is retrieved using the processor. One or more of the unfixed attributes of the retrieved template is fixed. The modified template is stored as a new template having a plurality fixed attributes and a plurality of unfixed attributes.

Abstract: The present invention provides a system and single or multi-functional element device that can be inserted and temporarily placed or implanted into a structure having a lumen or hollow space, such as a subject's abdominal cavity to provide therewith access to the site of interest in connection with minimally invasive surgical procedures. The insertable device may be configured such that the functional elements have various degrees of freedom of movement with respect to orienting the functional elements or elements to provide access to the site from multiple and different orientations/perspectives as the procedure dictates, e.g., to provide multiple selectable views of the site, and may provide a stereoscopic view of the site of interest.

Abstract: The present application describes techniques for fetching map data as a selected subset of entire map data available, by selecting map data tiles corresponding to an area that encompasses a first route and to an area encompassing a secondary route based on the first route. An amount of map data accessed may be adjusted based on a priority of the secondary route.

Abstract: A software development platform comprising one or more user-selectable modular units containing a vertical stack of back-end business logic. One or more user-selectable modular units containing domain model components. One or more user-selectable modular units containing front end presentation components. A virtual appliance comprising application-specific logic that includes one or more of the modular units containing the vertical stack of back-end business logic, one or more of the user-selectable modular units containing the domain model components and one or more of the user-selectable modular units containing front end presentation components.

Abstract: A method for template derivation comprising generating a plurality of templates using a processor, each template having a plurality of unfixed attributes. The plurality of templates are stored in a non-transient data memory. One of the plurality of templates is retrieved using the processor. One or more of the unfixed attributes of the retrieved template is fixed. The modified template is stored as a new template having a plurality fixed attributes and a plurality of unfixed attributes.

Abstract: A system for representing devices in a software application, comprising a plurality of templates, each having an associated device, each of the templates configured to be added to an operating software application. A plurality of resource models, each storing state data for one of the plurality of devices, each of resource models configured to be added to the operating software application. A plurality of drivers, each associated with one of the plurality of devices, each of the drivers configured to be added to the operating software application, and wherein the plurality of templates, the plurality of resource models and the plurality of drivers are stored in a non-transient electronic data memory as a single associated unit.