Abstract: Provided herein are microneedle particles, compositions that include microneedle particles, methods of treating skin, and methods of delivering a substance of interest. The microneedle particles may include one or more microneedles, and the microneedle particles may be configured to prevent the entire microneedle particle from penetrating the biological tissue. The microneedle particles may be dispersed in a liquid medium to form a composition. A biological tissue may be contacted with the microneedle particles to pre-treat the biological tissue, and a substance of interest may be applied to the pre-treated biological tissue.

Abstract: Provided herein are microneedle particles, compositions that include microneedle particles, methods of treating skin, and methods of delivering a substance of interest. The microneedle particles may include one or more microneedles, and the microneedle particles may be configured to prevent the entire microneedle particle from penetrating the biological tissue. The microneedle particles may be dispersed in a liquid medium to form a composition. A biological tissue may be contacted with the microneedle particles to pre-treat the biological tissue, and a substance of interest may be applied to the pre-treated biological tissue.

Abstract: Provided herein are microneedle particles, compositions that include microneedle particles, methods of treating skin, and methods of delivering a substance of interest. The microneedle particles may include one or more microneedles, and the microneedle particles may be configured to prevent the entire microneedle particle from penetrating the biological tissue. The microneedle particles may be dispersed in a liquid medium to form a composition. A biological tissue may be contacted with the microneedle particles to pre-treat the biological tissue, and a substance of interest may be applied to the pre-treated biological tissue.

Abstract: A wire bridge monitoring system includes a wire bridge (18) and a monitoring device (22, 24). The wire bridge (18) is used by a technician (20) during servicing an electrical or electro-mechanical installation (1) to bridge a component of the electrical or electro-mechanical installation (1). The wire bridge (18) has an electronic identification device (26) configured to transmit a radio signal (21) comprising an identification number of the wire bridge (18). The monitoring device (22, 24) has a transceiver (28, 37), a memory (23, 41) and a processor (31, 39). The transceiver (28, 37) receives the radio signal (21) transmitted by the electronic identification device (26) when within a predetermined radio range, and the memory (23, 41) records use of the wire bridge (18). The processor (31, 39) monitors if the wire bridge (18) is within the predetermined radio range, and generates an alarm if the wire bridge (18) is not within the predetermined radio range and the wire bridge (18) is recorded as being in use.