Patents by Inventor Andrew Takle

Andrew Takle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080108615
    Abstract: The present invention relates to compounds of formula (I): pharmaceutically acceptable salts thereof, corresponding pharmaceutical compositions, use as Raf Kinase Inhibitors and treatment methods for neurotraumatic diseases and cancer.
    Type: Application
    Filed: October 30, 2007
    Publication date: May 8, 2008
    Inventors: David Dean, Andrew Takle, David Wilson
  • Publication number: 20070259877
    Abstract: The invention provides compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Re, Rf and Y are as defined in the specification. The compounds are partial or full agonists at the growth hormone secretagogue (GHS) receptors. Pharmaceutical compositions comprising the compounds methods of preparing the compounds, uses of the compounds and methods involving the compounds are also provided.
    Type: Application
    Filed: July 26, 2005
    Publication date: November 8, 2007
    Inventors: David Dean, Alessandra Gaiba, Nigel King, Andrew Takle, Jason Witherington
  • Publication number: 20070244123
    Abstract: Compounds and their use as pharmaceuticals particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine or cardiac hypertrophy.
    Type: Application
    Filed: February 21, 2007
    Publication date: October 18, 2007
    Inventors: David Dean, Andrew Takle, David Wilson
  • Publication number: 20070135433
    Abstract: Novel compounds and their use as pharmaceuticals particularly as Raf kinase inhibitors for the treatment of neurotraumatic diseases, cancer, chronic neurodegeneration, pain, migraine and cardiac hypertrophy.
    Type: Application
    Filed: January 22, 2007
    Publication date: June 14, 2007
    Inventors: David DEAN, Andrew Takle, David Wilson
  • Publication number: 20060241149
    Abstract: Pyridinyl-benzoheterocycyl kinase inhibitor compounds are disclosed. Also disclosed are methods of making such compounds as well as methods of using the same in the treatment of diseases.
    Type: Application
    Filed: November 6, 2003
    Publication date: October 26, 2006
    Inventors: Jerry Adams, Deborah Bryan, Jiri Kasparec, Francis King, Andrew Takle, David Wilson, Steven Goodman
  • Publication number: 20060122207
    Abstract: Compounds of formula (I): wherein X is O, CH2, S or NH, or the moiety X—R1 is hydrogen; V is CH or N; R1 is hydrogen, C1-6alkyl, C3-7cycloalkyl, aryl, arylC1-6alkyl, heterocyclyl, heterocyclylC1-6alkyl, heteroaryl, or heteroarylC1-6alkyl any of which except for hydrogen may be optionally substituted; R2 and R3 independently represent optionally substituted C1-6alkyl, or R2 and R3 together with the carbon atom to which they are attached form an optionally substituted C3-7cycloalkyl or C3-7cycloalkenyl ring; or R2 and R3 together with the carbon atom to which they are attached form an optionally substituted 5 to 7-membered heterocyclyl ring containing up to 3 heteroatoms selected from N, O, S.
    Type: Application
    Filed: January 17, 2006
    Publication date: June 8, 2006
    Inventors: Jon Steadman, Andrew Takle
  • Publication number: 20050143393
    Abstract: Pleuromutilin compounds of the formula: are of use in anti-bacterial therapy.
    Type: Application
    Filed: November 12, 2001
    Publication date: June 30, 2005
    Inventors: David Dean, Antoinette Naylor, Andrew Takle