Patents by Inventor Andrew Thurston
Andrew Thurston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240130341Abstract: Genetically modified non-human animals that are immunodeficient and comprise xenotransplanted hepatocytes such as human hepatocytes, wherein the genetically modified non-human animal and/or the transplanted hepatocytes are modified to restore interleukin-6 (IL-6)/interleukin-6 receptor (IL-6R) signaling pathway activity or interleukin-6 receptor subunit beta (GP130) signaling pathway activity in the transplanted hepatocytes, are provided. Also provided are methods of assessing the activity of human-liver-targeting reagents in such non-human animals and methods of making animals with a humanized liver (e.g., with reduced steatosis). Also provided are genetically modified non-human animals comprising an inactivated endogenous Rag2 gene, an inactivated endogenous Il2rg gene, an inactivated endogenous Fah gene, a humanized IL6 gene, and optionally an inactivated endogenous Rag1 gene and methods of using and making such animals.Type: ApplicationFiled: September 28, 2023Publication date: April 25, 2024Inventors: Joseph Zhe Li, Marisa Carbonaro, Gavin Thurston, Andrew J. Murphy
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Patent number: 11937587Abstract: Non-human animals, expressing humanized CD3 proteins are provided. Non-human animals, e.g., rodents, genetically modified to comprise in their genome humanized CD3 proteins are also provided. Additionally, provided are methods and compositions of making such non-human animals, as well as methods of using said non-human animals.Type: GrantFiled: December 10, 2020Date of Patent: March 26, 2024Assignee: Regeneron Pharmaceuticals, Inc.Inventors: Kara L. Olson, Eric Smith, Ka-Man Venus Lai, Andrew J. Murphy, Gavin Thurston, Dayong Guo
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Patent number: 11669362Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: GrantFiled: April 25, 2022Date of Patent: June 6, 2023Assignee: Amazon Technologies, Inc.Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Publication number: 20220357972Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: ApplicationFiled: April 25, 2022Publication date: November 10, 2022Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Publication number: 20220283867Abstract: Various embodiments of the present application set forth a computer-implemented method comprising receiving, from a client, a request for a workstation instance having a first configuration, in response to the request, generating a first workstation pool associated with the first configuration, wherein the first workstation pool includes at least two unassigned workstation instances having the first configuration, and assigning at least a first workstation instance included in the at least two unassigned workstation instances to the client.Type: ApplicationFiled: March 5, 2021Publication date: September 8, 2022Inventors: Kevin Ibraheem KELANI, Airan LANDAU, Kevin L. CURETON, Marian MONTAGNINO, Michelle Lynne BRENNER, Thomas A. CELLUCCI, Anna J. BROSNAHAN, William Andrew THURSTON
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Patent number: 11314541Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: GrantFiled: June 5, 2020Date of Patent: April 26, 2022Assignee: Amazon Technologies, Inc.Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Patent number: 10838756Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: GrantFiled: June 8, 2018Date of Patent: November 17, 2020Assignee: Amazon Technologies, Inc.Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Publication number: 20200301726Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: ApplicationFiled: June 5, 2020Publication date: September 24, 2020Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Patent number: 10725812Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: GrantFiled: June 8, 2018Date of Patent: July 28, 2020Assignee: Amazon Technologies, Inc.Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Patent number: 10678582Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: GrantFiled: June 8, 2018Date of Patent: June 9, 2020Assignee: Amazon Technologies, Inc.Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Patent number: 10396828Abstract: A mobile device may include a plurality of hardware devices. The physical devices may be virtualized to enable efficient access and utilization. Furthermore, the mobile device may support containerization of applications executed by the hardware devices. The virtualized physical devices may be provided to various containers executed by the mobile device. Furthermore, a priority mechanism may be used to manage container access to the physical devices.Type: GrantFiled: July 16, 2018Date of Patent: August 27, 2019Assignee: Amazon Technologies, Inc.Inventors: Tipu Saleem Qureshi, Deepak Singh, William Andrew Thurston
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Publication number: 20190108049Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: ApplicationFiled: June 8, 2018Publication date: April 11, 2019Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Publication number: 20180323812Abstract: A mobile device may include a plurality of hardware devices. The physical devices may be virtualized to enable efficient access and utilization. Furthermore, the mobile device may support containerization of applications executed by the hardware devices. The virtualized physical devices may be provided to various containers executed by the mobile device. Furthermore, a priority mechanism may be used to manage container access to the physical devices.Type: ApplicationFiled: July 16, 2018Publication date: November 8, 2018Inventors: Tipu Saleem Qureshi, Deepak Singh, William Andrew Thurston
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Patent number: 10027351Abstract: A mobile device may include a plurality of physical antennas configured to receive and transmit data. The physical antennas may be virtualized to enable efficient access and utilization of the computing resources of the physical antenna. Furthermore, the mobile device may support containerization of application executed by the mobile device. The virtualized physical antennas may be provided to various containers executed by the mobile device. Furthermore, a priority mechanism may be used to manage container access to the physical antennas.Type: GrantFiled: December 8, 2015Date of Patent: July 17, 2018Assignee: Amazon Technologies, Inc.Inventors: Tipu Saleem Qureshi, Deepak Singh, William Andrew Thurston
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Patent number: 10007509Abstract: A mobile device may provide virtualization of physical resources and containerization of software application. Various deployment strategies such as, a blue-green deployment strategy, may be utilized to perform application and other software updates between various containers of a mobile device. State information and other information from an active container may be provided to the update container during handover operations.Type: GrantFiled: December 8, 2015Date of Patent: June 26, 2018Assignee: Amazon Technologies, Inc.Inventors: Tipu Saleem Qureshi, Deepak Singh, William Andrew Thurston
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Patent number: 9996380Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: GrantFiled: January 26, 2016Date of Patent: June 12, 2018Assignee: Amazon Technologies, Inc.Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Publication number: 20160162320Abstract: A task definition is received. The task definition indicates at least a location from which one or more software image can be obtained and information usable to determine an amount of resources to allocate to one or more software containers for the one or more software image. A set of virtual machine instances in which to launch the one or more software containers is determined, the one or more software image is obtained from the location included in the task definition and is launched as the one or more of software containers within the set of virtual machine instances.Type: ApplicationFiled: January 26, 2016Publication date: June 9, 2016Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Patent number: 9256467Abstract: A system and method for a container service that obtains a software image of a software container that has been configured to be executed within a computer system instance registered to a cluster by one or more processors. The container service is configured to receive a request to launch the software image in accordance with a task definition, wherein the task definition specifies an allocation of resources for the software container. The container service may then determine, according to a placement scheme, a subset of a set of container instances registered to the cluster in which to launch the software image in accordance with the task definition. Upon determining the subset of the set of container instances, the container service may launch the software image as one or more running software containers in the set of container instances in accordance with the task definition.Type: GrantFiled: November 11, 2014Date of Patent: February 9, 2016Assignee: Amazon Technologies, Inc.Inventors: Deepak Singh, Anthony Joseph Suarez, William Andrew Thurston, Anirudh Balachandra Aithal, Daniel Robert Gerdesmeier, Euan Skyler Kemp, Kiran Kumar Meduri, Muhammad Umer Azad
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Patent number: 7443939Abstract: The invention provides a receiver that is capable of deducing the timing of a received signal having a frame structure and corresponding methods. Each frame contains a synchronization word. The receiver correlates the known synchronization word against the received signal to determine the position of the synchronization word. The correlation results can be accumulated over several frames' worth of the signal in order to enhance the determination. The frame boundaries within the signal can be translated and the process of determining the synchronization word position can then be repeated. In this manner, several results for the synchronization word position can be obtained and the best selected. A thresholding process can be used to curtail the number of frames' worth of the received signal that needs to be processed and a mechanism is provided to prevent the thresholding process from biasing the determination of the synchronization word position.Type: GrantFiled: November 1, 2001Date of Patent: October 28, 2008Assignee: Ubinetics LimitedInventor: Andrew Thurston
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Patent number: 7257150Abstract: An input signal is mixed with a scrambling code and with an OVSF code, and then accumulated over a period of time equal to one symbol of the pilot channel before being reset. The resultant complex signals are mixed with the conjugate of complex signals provided by a pilot pattern generator, with the result being fed to a delay line (22). A multiplier multiplies the complex value at a location P(n) in the delay line (22) by the conjugate of a complex value at another location P(n+k), and provides the resulting complex number (which is a complex vector whose phase is a coherent measurement of the phase rotation occurring between the symbols corresponding to the two locations) at an output (27). The real part of the complex signal provided at the output (27) is provided to a first combiner (30), and the imaginary part is provided to a second combiner (31). These combiners (30, 31) also receive corresponding signals from all of the other fingers (not shown) of the rake receiver.Type: GrantFiled: November 20, 2001Date of Patent: August 14, 2007Inventors: Diego Giancola, Andrew Thurston, Jonathan Lucas