Patents by Inventor Andrew Torda

Andrew Torda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP
    Publication number: 20230183685
    Abstract: The invention relates to a synthetic transfer RNA with an extended anticodon loop. The invention provides a synthetic suppressor transfer RNA useful for the treatment of a genetic disease like cystic fibrosis associated with a nonsense mutation. The synthetic transfer RNA contains an extended anticodon loop with two consecutive anticodon base triplets configured to base-pair to two consecutive codon base triplets on an mRNA. The first anticodon base triplet or the second anticodon base triplet is configured to base-pair to a stop codon base triplet on the mRNA.
    Type: Application
    Filed: July 29, 2022
    Publication date: June 15, 2023
    Inventors: Zoya IGNATOVA, Andrew TORDA, Marco MATTHIES
  • Synthetic transfer RNA with extended anticodon loop
    Patent number: 11434485
    Abstract: A synthetic transfer RNA with an extended anticodon loop. A synthetic suppressor transfer RNA useful for the treatment of a genetic disease like cystic fibrosis associated with a nonsense mutation. The synthetic transfer RNA contains an extended anticodon loop with two consecutive anticodon base triplets configured to base-pair to two consecutive codon base triplets on an mRNA. The first anticodon base triplet or the second anticodon base triplet is configured to base-pair to a stop codon base triplet on the mRNA.
    Type: Grant
    Filed: March 14, 2019
    Date of Patent: September 6, 2022
    Assignee: ARCTURUS THERAPEUTICS, INC.
    Inventors: Zoya Ignatova, Andrew Torda, Marco Matthies
  • SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP
    Publication number: 20220162612
    Abstract: The invention relates to a synthetic transfer RNA with an extended anticodon loop. The invention provides a synthetic suppressor transfer RNA useful for the treatment of a genetic disease like neurofibromatosis associated with a frameshift mutation. The synthetic transfer RNA comprises an extended anticodon loop having a four-nucleotide anticodon or a five-nucleotide anticodon.
    Type: Application
    Filed: April 9, 2020
    Publication date: May 26, 2022
    Inventors: Zoya IGNATOVA, Andrew TORDA
  • SYNTHETIC TRANSFER RNA WITH EXTENDED ANTICODON LOOP
    Publication number: 20200407714
    Abstract: A synthetic transfer RNA with an extended anticodon loop. A synthetic suppressor transfer RNA useful for the treatment of a genetic disease like cystic fibrosis associated with a nonsense mutation. The synthetic transfer RNA contains an extended anticodon loop with two consecutive anticodon base triplets configured to base-pair to two consecutive codon base triplets on an mRNA. The first anticodon base triplet or the second anticodon base triplet is configured to base-pair to a stop codon base triplet on the mRNA.
    Type: Application
    Filed: March 14, 2019
    Publication date: December 31, 2020
    Inventors: Zoya Ignatova, Andrew Torda, Marco Matthies