Abstract: The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II.

Abstract: A series of substituted imidazo[1,2-b]pyridazine derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.

Abstract: Embodiments may relate to a vehicle comprising: a sensor to identify, based on an audio or visual condition, the occurrence of a condition related to a passenger of the vehicle. The vehicle may further include a processor coupled with the sensor. The processor may be configured to identify, in a user profile of the first passenger of the vehicle, a pre-identified action. The processor may further be configured to perform, or facilitate the performance of, the pre-identified action by the vehicle based on the occurrence of the audio or visual condition. Other embodiments may be described or claimed.

Abstract: A three-dimensional print head apparatus may include a securing mechanism, a hopper, a nozzle, a heating system, and a fume extraction system. The securing mechanism may be adapted to secure to a wrist joint of a robotic arm. The hopper may have a cavity and a lower aperture and may be secured to the securing mechanism. The nozzle may have an upper aperture and a lower aperture. The heating system may be positioned along the barrel.

Abstract: A computer-implemented system, method and computer-program product are configured to receive an image of a location from at least one image sensor device; analyze the image to determine a distance between a person and an object in the image; and output a control signal when the determined distance between the person and the object is below a predetermined threshold distance. The control signal causes an electronic device at the location to perform an action related to the distance between the person and the object. The object may be another person.

Abstract: Methods, computer systems, and computer storage media are provided for enabling the reuse of data structures, data processing, data cleaning, data mapping, analytic concepts, analytic widgets, logic, and graphical components to efficiently provide custom insights to new areas. Additionally, the reuse of data structures, data processing, data cleaning, data mapping, analytic concepts, analytic widgets, logic, and graphical components created for a single model can also be reused components across new models, which enables new models to be efficiently created for a completely separate set of analytics. A model is inimitably created by creating, cleaning, and/or mapping a data concept and creating widgets that provide analytic capabilities for the model. These data concepts and widgets are specifically designed to be reused across models and model instances for a plurality of clients or users. Any data concepts and widgets of the model can also be modified to provide a customized solution.

Abstract: A dry powder inhaler comprises an airway (1) along which, in use, air is drawn from an upstream, inlet end (2) to a downstream, outlet end (3). The airway (1) includes a medicament presentation region (4) at which, in use, a dose of medicament is presented to the airway (1), a primary air inlet (10), and a barrel (5) extending from the medicament presentation region (4) to the outlet end (3) of the airway (1). The inlet end of the barrel (5) is of reduced internal dimension relative to the medicament presentation region (4) and relative to the outlet end of the barrel (5), such that the inlet end of the barrel (5) constitutes a constriction of the airway (1). At least one secondary air inlet (11) is disposed such that, in use, air enters the airway (1) from the secondary air inlet (11) in a direction that is substantially orthogonal to the direction of flow of air along said barrel (5).

Abstract: Methods and systems are disclosed for predicting species invasions. Native species occurrence information and native environmental information are received. At least one ecological niche model is formulated based on the native species occurrence information and the native environmental information. Target environmental information corresponding to an alternative geography is received. The ecological niche model is projected onto the alternative geography to predict characteristics of an invasion of the species.

Abstract: Methods and systems are disclosed for predicting species invasions. Native species occurrence information and native environmental information are received. At least one ecological niche model is formulated based on the native species occurrence information and the native environmental information. Target environmental information corresponding to an alternative geography is received. The ecological niche model is projected onto the alternative geography to predict characteristics of an invasion of the species.

Abstract: A container including at most two first cavities for receiving an ophthalmic lens, and a second cavity for the removal of fluid from the or each first cavity, the second cavity being laterally spaced from, and in communication with, the or each first cavity, wherein each cavity has an opening on the same face of the container.