Abstract: A computer implemented system and method for managing and tracking cargo shipments through a supply chain. The system includes a core domain and a party domain. In the core domain, electronic representations of one or more core processes may be generated and maintained that includes a sequence of events and/or milestones representing real world actions associated with the shipping chain. In the party domain, electronic representations of one or more party processes may be generated and maintained that represent a sequence of various events and/or milestones that a party to the shipping chain must undertake. The core domain may generate and communicate events representative of actions that have been or should be undertaken by the parties. The events may be communicated to the party domain where the events can trigger or realize milestones indicating to the party it should undertake various real world actions relating to the shipping chain.

Abstract: A coating for an implantable medical device is provided comprising a first layer including a first polymer and a second layer including a second polymer. The second layer is disposed over at least a portion of the first layer. The second polymer has a lower degree of hydration than the first polymer.

Abstract: A medical article is disclosed, comprising a biologically degradable AB block copolymer and a biologically degradable polymer that is capable, at equilibrium and at room temperature, of absorbing less than about 5 mass % water.

Abstract: Methods for fabricating coatings for implantable medical devices are disclosed. The coatings include hydrophilic and hydrophobic components. The methods provide for treatment of the coatings to cause enrichment a region close to, at or on the outer surface of the coating with the hydrophilic component.

Abstract: A stent comprising a coating layer is disclosed. The coating layer has a hydrophobic component and a hydrophilic component, wherein a region of the coating layer on or about the outermost surface of the coating layer has a higher content or concentration of the hydrophilic component than the hydrophobic component.

Abstract: An implantable medical device, such as a stent, is disclosed having a coating. The coating includes a poly(butylene terephthalate-co-ethylene glycol) polymer. The coating can also include a drug.