Patents by Inventor Andrew V. Anzalone

Andrew V. Anzalone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR EDITING NUCLEOTIDE SEQUENCES
    Publication number: 20240067940
    Abstract: Disclosed herein, are prime editors for prime editing. Also disclosed are engineered reverse transcriptases and methods of using same for prime editing.
    Type: Application
    Filed: September 29, 2023
    Publication date: February 29, 2024
    Inventors: Christopher WILSON, Andrew V. ANZALONE, Jonathan M. LEVY
  • GENOME EDITING COMPOSITIONS AND METHODS FOR TREATMENT OF CHRONIC GRANULOMATOUS DISEASE
    Publication number: 20240011007
    Abstract: Provided herein are compositions and methods of using prime editing systems comprising prime editors and prime editing guide RNAs for treatment of genetic disorders.
    Type: Application
    Filed: August 14, 2023
    Publication date: January 11, 2024
    Inventors: Jennifer Gori, David Waterman, Jack Heath, Andrew V. Anzalone
  • GENETICALLY ENCODED RATIOMETRIC FLUORESCENT BARCODES
    Publication number: 20210364523
    Abstract: The disclosed subject matter relates to nucleic acid constructs that encode one or more fluorescent proteins, which can function as intracellular fluorescent tags, specifically for flow cytometry and fluorescence microscopy. The present disclosure further provides genetically-engineered cells that include one or more nucleic acid constructs and methods for using such genetically-engineered cells and nucleic acid constructs.
    Type: Application
    Filed: June 14, 2021
    Publication date: November 25, 2021
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Andrew V. Anzalone, Virginia W. Cornish, Miguel Jimenez