Patents by Inventor Andrew V. Kossenkov

Andrew V. Kossenkov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSTIONS AND METHODS FOR DIAGNOSING LUNG CANCERS USING GENE EXPRESSION PROFILES
    Publication number: 20210079479
    Abstract: Methods and compositions are provided for diagnosing lung cancer in a mammalian subject by use of 7 or more selected genes, e.g., a gene expression profile, from the blood of the subject which is characteristic of disease. The gene expression profile includes 7 or more genes of Table I, Table II, Table III, Table IV or Table IX herein.
    Type: Application
    Filed: December 19, 2018
    Publication date: March 18, 2021
    Inventors: Michael Showe, Louise C. Showe, Andrew V. Kossenkov
  • Biomarkers in Peripheral Blood Mononuclear Cells for Diagnosing or Detecting Lung Cancers
    Publication number: 20200370127
    Abstract: Methods and compositions are provided for diagnosing or detecting a condition, e.g., lung disease in a mammalian subject by use of a micro-RNA expression level or an expression level profile of multiple miRNA in the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of COPD or NSCLC. Detection of changes in expression in specific miRNA biomarkers from that of a reference sample or miRNA expression profile are correlated with non-small cell lung cancer (NSCLC) and/or COPD and permit differentiation among healthy subjects, subjects with COPD and subjects with adenocarcinoma or squamous cell carcinoma.
    Type: Application
    Filed: April 30, 2020
    Publication date: November 26, 2020
    Inventors: Louise C. SHOWE, Michael SHOWE, Andrew V. KOSSENKOV, Elena NIKONOVA
  • Biomarkers in Peripheral Blood Mononuclear Cells for Diagnosing or Detecting Lung Cancers
    Publication number: 20180251853
    Abstract: Methods and compositions are provided for diagnosing or detecting a condition, e.g., lung disease in a mammalian subject by use of a micro-RNA expression level or an expression level profile of multiple miRNA in the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of COPD or NSCLC. Detection of changes in expression in specific miRNA biomarkers from that of a reference sample or miRNA expression profile are correlated with non-small cell lung cancer (NSCLC) and/or COPD and permit differentiation among healthy subjects, subjects with COPD and subjects with adenocarcinoma or squamous cell carcinoma.
    Type: Application
    Filed: February 26, 2018
    Publication date: September 6, 2018
    Inventors: Louise C. SHOWE, Michael SHOWE, Andrew V. KOSSENKOV, Elena NIKONOVA
  • Biomarkers in peripheral blood mononuclear cells for diagnosing or detecting lung cancers
    Patent number: 9920375
    Abstract: Methods and compositions are provided for diagnosing or detecting a condition, e.g., lung disease in a mammalian subject by use of a micro-RNA expression level or an expression level profile of multiple miRNA in the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of COPD or NSCLC. Detection of changes in expression in specific miRNA biomarkers from that of a reference sample or miRNA expression profile are correlated with non-small cell lung cancer (NSCLC) and/or COPD and permit differentiation among healthy subjects, subjects with COPD and subjects with adenocarcinoma or squamous cell carcinoma.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: March 20, 2018
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Louise C. Showe, Michael Showe, Andrew V. Kossenkov, Elena Nikonova
  • Biomarkers in Peripheral Blood Mononuclear Cells for Diagnosing or Detecting Lung Cancers
    Publication number: 20150252441
    Abstract: Methods and compositions are provided for diagnosing or detecting a condition, e.g., lung disease in a mammalian subject by use of a micro-RNA expression level or an expression level profile of multiple miRNA in the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of COPD or NSCLC. Detection of changes in expression in specific miRNA biomarkers from that of a reference sample or miRNA expression profile are correlated with non-small cell lung cancer (NSCLC) and/or COPD and permit differentiation among healthy subjects, subjects with COPD and subjects with adenocarcinoma or squamous cell carcinoma.
    Type: Application
    Filed: May 22, 2015
    Publication date: September 10, 2015
    Inventors: Louise C. SHOWE, Michael SHOWE, Andrew V. KOSSENKOV, Elena NIKONOVA
  • Biomarkers in peripheral blood mononuclear cells for diagnosing or detecting lung cancers
    Patent number: 9068974
    Abstract: Methods and compositions are provided for diagnosing or detecting a condition, e.g., lung disease in a mammalian subject by use of a micro-RNA expression level or an expression level profile of multiple miRNA in the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of COPD or NSCLC. Detection of changes in expression in specific miRNA biomarkers from that of a reference sample or miRNA expression profile are correlated with non-small cell lung cancer (NSCLC) and/or COPD and permit differentiation among healthy subjects, subjects with COPD and subjects with adenocarcinoma or squamous cell carcinoma.
    Type: Grant
    Filed: November 6, 2009
    Date of Patent: June 30, 2015
    Assignee: THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY
    Inventors: Louise C. Showe, Michael Showe, Andrew V. Kossenkov, Elena Nikonova
  • Biomarkers in Peripheral Blood Mononuclear Cells for Diagnosing or Detecting Lung Cancers
    Publication number: 20110251098
    Abstract: Methods and compositions are provided for diagnosing or detecting a condition, e.g., lung disease in a mammalian subject by use of a micro-RNA expression level or an expression level profile of multiple miRNA in the peripheral blood mononuclear cells (PBMC) of the subject which is characteristic of COPD or NSCLC. Detection of changes in expression in specific miRNA biomarkers from that of a reference sample or miRNA expression profile are correlated with non-small cell lung cancer (NSCLC) and/or COPD and permit differentiation among healthy subjects, subjects with COPD and subjects with adenocarcinoma or squamous cell carcinoma.
    Type: Application
    Filed: November 6, 2009
    Publication date: October 13, 2011
    Inventors: Louise C. Showe, Michael Showe, Andrew V. Kossenkov, Elena Nikonova