Patents by Inventor Andrew Vaino

Andrew Vaino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pantothenate derivatives for the treatment of neurological disorders
    Patent number: 10407447
    Abstract: Compounds having the following formula (E): or a pharmaceutically acceptable salt thereof, wherein R, R?, R?, X and n are as defined herein are provided. Methods comprising use of such compounds for the treatment of neurologic disorders, such as pantothenate kinase-associated neurodegeneration, and pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders are also provided.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: September 10, 2019
    Assignee: Retrophin, Inc.
    Inventors: Andrew Vaino, Marek Biestek, Martin Shkreli
  • PANTOTHENATE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
    Publication number: 20180291045
    Abstract: Compounds having the following formula (E): or a pharmaceutically acceptable salt thereof, wherein R, R?, R?, X and n are as defined herein are provided. Methods comprising use of such compounds for the treatment of neurologic disorders, such as pantothenate kinase-associated neurodegeneration, and pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders are also provided.
    Type: Application
    Filed: January 5, 2018
    Publication date: October 11, 2018
    Inventors: Andrew Vaino, Marek Biestek, Martin Shkreli
  • Pantothenate derivatives for the treatment of neurological disorders
    Patent number: 9896464
    Abstract: Compounds having the following formula (E): Formula E or a pharmaceutically acceptable salt thereof, wherein R, R?, R?, X and n are as defined herein are provided. Methods comprising use of such compounds for the treatment of neurologic disorders, such as pantothenate kinase-associated neurodegeneration, and pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders are also provided.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: February 20, 2018
    Assignee: Retrophin, Inc.
    Inventors: Andrew Vaino, Marek Biestek, Martin Shkreli
  • Pantothenate derivatives for the treatment of neurologic disorders
    Patent number: 9629862
    Abstract: The present disclosure relates to pantothenate derivatives for the treatment of neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: April 25, 2017
    Assignee: Retrophin, Inc.
    Inventors: Andrew Vaino, Marek Biestek, Martin Shkreli
  • PANOTHENATE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
    Publication number: 20160264607
    Abstract: Compounds having the following formula (E): Formula E or a pharmaceutically acceptable salt thereof, wherein R, R?, R?, X and n are as defined herein are provided. Methods comprising use of such compounds for the treatment of neurologic disorders, such as pantothenate kinase-associated neurodegeneration, and pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders are also provided.
    Type: Application
    Filed: October 27, 2014
    Publication date: September 15, 2016
    Inventors: Andrew Vaino, Marek Biestek, Martin Shkreli
  • PANTOTHENATE DERIVATIVES FOR THE TREATMENT OF NEUROLOGIC DISORDERS
    Publication number: 20160015727
    Abstract: The present disclosure relates to pantothenate derivatives for the treatment of neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders.
    Type: Application
    Filed: September 30, 2015
    Publication date: January 21, 2016
    Inventors: Andrew Vaino, Marek Biestek, Martin Shkreli
  • Pantothenate derivatives for the treatment of neurologic disorders
    Patent number: 9181286
    Abstract: The present disclosure relates to pantothenate derivatives for the treatment of neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: November 10, 2015
    Assignee: Retrophin, Inc.
    Inventors: Andrew Vaino, Marek Biestek, Martin Shkreli
  • PANTOTHENATE DERIVATIVES FOR THE TREATMENT OF NEUROLOGIC DISORDERS
    Publication number: 20140135294
    Abstract: The present disclosure relates to pantothenate derivatives for the treatment of neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Applicant: Retrophin, Inc.
    Inventors: Andrew VAINO, Marek Biestek, Martin Shkreli
  • Pantothenate derivatives for the treatment of neurologic disorders
    Patent number: 8673883
    Abstract: The present disclosure relates to pantothenate derivatives for the treatment of neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders.
    Type: Grant
    Filed: April 26, 2013
    Date of Patent: March 18, 2014
    Assignee: Retrophin, Inc.
    Inventors: Andrew Vaino, Marek Biestek, Martin Shkreli
  • PANTOTHENATE DERIVATIVES FOR THE TREATMENT OF NEUROLOGIC DISORDERS
    Publication number: 20130289001
    Abstract: The present disclosure relates to pantothenate derivatives for the treatment of neurologic disorders (such as pantothenate kinase-associated neurodegeneration), pharmaceutical compositions containing such compounds, and their use in treatment of neurologic disorders.
    Type: Application
    Filed: April 26, 2013
    Publication date: October 31, 2013
    Applicant: Retrophin, Inc.
    Inventors: Andrew VAINO, Marek Biestek, Martin Shkreli
  • BICYCLIC PYRAZOLO PROTEIN KINASE MODULATORS
    Publication number: 20100179190
    Abstract: The present invention provides novel bicyclic pyrazolo kinase modulators and methods of using the novel bicyclic pyrazolo kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: November 14, 2008
    Publication date: July 15, 2010
    Applicant: SGX PHARMACEUTICALS, INC.
    Inventors: Pierre-Yves Bounaud, Andrew Vaino
  • Bicyclic pyrazolo protein kinase modulators
    Patent number: 7473783
    Abstract: The present invention provides novel bicyclic pyrazolo kinase modulators and methods of using the novel bicyclic pyrazolo kinase modulators to treat diseases mediated by kinase activity.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: January 6, 2009
    Assignee: SGX Pharmaceuticals, Inc.
    Inventors: Pierre-Yves Bounaud, Andrew Vaino
  • Bicyclic pyrazolo protein kinase modulators
    Publication number: 20050176786
    Abstract: The present invention provides novel bicyclic pyrazolo kinase modulators and methods of using the novel bicyclic pyrazolo kinase modulators to treat diseases mediated by kinase activity.
    Type: Application
    Filed: December 17, 2004
    Publication date: August 11, 2005
    Applicant: Structural GenomiX
    Inventors: Pierre-Yves Bounaud, Andrew Vaino